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Life and health

72,234 articles

Christopher S. Henney

Christopher S. Henney is a British-born immunologist who moved from T-cell research at the Fred Hutchinson Cancer Research Center to co-founding Seattle biotech firms Immunex, ICOS, and Dendreon.

Christopher S. Wilcox

Christopher S. Wilcox is a British-born physician-scientist in renal physiology and hypertension who led Georgetown University's nephrology division and researched oxidative stress as a cause of hypertension.

Christopher Semsarian

Christopher Semsarian AM is an Australian cardiologist and Professor of Medicine at the University of Sydney known for research into the genetic causes of sudden cardiac death in young people.

Christopher Somerville

Christopher R. Somerville is a plant biologist elected to the U.S. National Academy of Sciences in 1996, known for establishing Arabidopsis thaliana as a model organism for plant genetics.

Christopher Summerfield

Christopher Summerfield is a British cognitive neuroscientist, Professor at Oxford and Research Director at the UK AI Security Institute, who studies how humans learn and decide.

Christopher T. Walsh

Christopher T. Walsh (1944–2023) was an American biochemist known for the enzyme mechanisms of antibiotic action, resistance, and bacterial natural product biosynthesis, at MIT, Harvard, and Stanford.

Christopher Tate (structural biologist)

Christopher G. Tate is a membrane protein biochemist and structural biologist at the MRC Laboratory of Molecular Biology, Cambridge, known for GPCR structures, conformational thermostabilisation, and mini-G proteins.

Christopher U.T. Hellen

Christopher U.T. Hellen is a molecular biologist and Associate Professor of Cell Biology at SUNY Downstate in Brooklyn, New York, known for defining roles of initiation factors eIF1, eIF1A, and eIF5B.

Christopher V. Nicchitta

Christopher V. Nicchitta is a cell biologist at Duke University who studies how the endoplasmic reticulum serves as a site of mRNA translation and protein synthesis.

Christopher V. Plowe

Christopher V. Plowe is an American physician-scientist who studies drug-resistant malaria, directs the Duke Global Health Institute since 2018, and validated the molecular marker for chloroquine resistance.

Christopher Vakoc

Christopher R. Vakoc is an American cancer biologist at Cold Spring Harbor Laboratory who studies epigenetic regulation in leukemia and pancreatic cancer, known for identifying BRD4 as a leukemia drug target.

Christopher W. Akey

Christopher W. Akey is a structural biologist and professor at Boston University's medical school known for cryo-EM structures of the yeast nuclear pore complex and other transport machines.

Christopher W.G. Redman

Christopher W.G. Redman (1941–2024) was a British obstetrician at Oxford who pioneered research on pre-eclampsia, held the world's first Chair of Obstetric Medicine, and created the Dawes-Redman fetal heart rate system used in over 130 countries.

Christopher Wright

Christopher Wright is an associate professor of STEM education at Drexel University who received the PECASE award for studying how African American boys develop engineering identities.

Christos A. Athanasoulis

Christos A. Athanasoulis is a vascular and interventional radiologist at Massachusetts General Hospital and Harvard Medical School whose 1974 and 1980 New England Journal of Medicine papers established therapeutic angiography.

Christos Coutifaris

Christos Coutifaris is an American reproductive endocrinologist and physician-scientist at the University of Pennsylvania, known for leading landmark infertility drug trials and research on embryo implantation and epigenetics.

Christos Davatzikos

Christos Davatzikos (Χρήστος Δαβατζίκος) is a Greek researcher in biomedical image analysis and machine learning for radiology, the Wallace T. Miller Sr. Professor of Radiology at the University of Pennsylvania.

Christos S. Mantzoros

Christos S. Mantzoros is a physician-scientist in endocrinology and metabolism at Harvard Medical School and Beth Israel Deaconess Medical Center, known for his research on the hormone leptin.

Christos Sotiriou

Christos Sotiriou is a medical oncologist and breast cancer genomics researcher who leads the J.-C. Heuson Breast Cancer Translational Research Laboratory at the Institut Jules Bordet in Brussels and is known for the Genomic Grade Index.

CHRNA3

CHRNA3, the cholinergic receptor nicotinic alpha 3 gene at 15q25.1 in the CHRNA5-A3-B4 cluster, encodes the α3 nicotinic acetylcholine receptor subunit, key to ganglionic transmission, nicotine dependence genetics, and CAKUT-dysautonomia.

CHRNA4

CHRNA4 (cholinergic receptor nicotinic alpha 4 subunit, HGNC:1958) is a human chromosome 20 gene encoding the alpha-4 nicotinic acetylcholine receptor subunit; gain-of-function mutations cause sleep-related hypermotor epilepsy and variants affect nicotine dependence.

CHRNA5

CHRNA5 (LNCR2), chromosome 15q25.1 gene encoding the α5 nicotinic acetylcholine receptor subunit; its rs16969968 D398N variant predicts nicotine dependence, smoking cessation age, and lung cancer risk in Europeans.

CHRNA7

CHRNA7 (a7nAChR, HGNC:1960) is the human chromosome 15q13.3 gene encoding the alpha-7 nicotinic acetylcholine receptor subunit, a homopentameric calcium-permeable ion channel; its partial duplication formed the human-specific dominant-negative gene CHRFAM7A.

Chroicocephalus

Chroicocephalus (Eyton, 1836) is a gull genus of the masked-gull clade in Laridae, revived after Pons et al. 2005 mtDNA work showed Larus paraphyletic; includes Black-headed, Bonaparte's, Gray-hooded, Slender-billed, Silver, and Andean Gulls.

Chromafenozide

Chromafenozide (ANS-118) is a dibenzoylhydrazine, non-steroidal ecdysone agonist insecticide from Nippon Kayaku and Sankyo, lepidopteran-specific, sold as MATRIC; EU-approved 2015, approval expired 31 March 2025 without renewal.

Chromaffin cell

Chromaffin cell: neuroendocrine cell of the adrenal medulla and paraganglia, named by Alfred Kohn for chromium staining; neural crest-derived, secretes epinephrine and norepinephrine for the fight-or-flight response.

Chromaffin cell of adrenal gland

Adrenal chromaffin cell (chromaffin cells, adrenal medulla): neural crest-derived neuroendocrine cell storing epinephrine and norepinephrine vesicles, triggered by splanchnic acetylcholine and PACAP during stress; origin revised to Schwann cell precursors.

Chromate transporter, long chain

Long-chain chromate transporter (LCHR, InterPro IPR014047): bidomain ~400-aa branch of the CHR superfamily, including ChrA efflux pumps with 10 transmembrane segments in a 4+6 arrangement that export toxic chromate using the proton motive force.

Chromatin

Chromatin: the DNA, RNA, and protein complex forming eukaryotic chromosomes; DNA wraps around histones in nucleosomes, packaging roughly 2 m of human DNA into a 5-10 micrometer nucleus and regulating gene access.

Chromatin accessibility assay

A chromatin accessibility assay measures which genome regions are physically open in a cell population, identifying regulatory elements where transcription factors and other DNA-binding proteins can access DNA.