Life and health

Conteltinib

Conteltinib (CT-707, 康特替尼, brand 首要泽) is Shouyao Holdings' second-generation ALK/FAK/Pyk2/IGF-1R inhibitor for ALK-positive NSCLC, approved by China's NMPA on June 10, 2026 as the first granule-formulation ALK inhibitor after a phase 3 win over crizotinib.

Contia

Contia, the sharp-tailed snakes, is a genus of two small slug-eating snakes of western North America: C. tenuis (Common Sharp-tailed Snake) and C. longicauda (Forest Sharp-tailed Snake), split in 2010, distinguished by caudal scale counts and tail length, Endangered in Canada.

Continent Urinary Reservoirs

Continent urinary reservoirs (Kock, Indiana, Mainz pouches; orthotopic neobladder) are surgically created intestinal pouches that store urine after cystectomy and are emptied by catheterization, avoiding an external bag.

Contingency management

Contingency management is a behavioral treatment for substance use disorders that delivers vouchers, gift cards, or prize draws when drug tests verify abstinence, ranked best for stimulant use disorder.

Continuous ambulatory peritoneal dialysis

Continuous ambulatory peritoneal dialysis (CAPD) is a home dialysis for kidney failure in which the peritoneal membrane filters waste as patients manually exchange fluid several times daily, without a machine.

Continuous arterial spin labeling

Continuous arterial spin labeling (CASL) is a magnetic resonance perfusion technique that magnetically labels arterial blood water to quantify cerebral blood flow without contrast agents or radiation.

Continuous blood pressure monitoring

Continuous blood pressure monitoring is the beat-by-beat measurement of arterial pressure during surgery and critical care, with the invasive arterial catheter as the gold standard and noninvasive finger-cuff devices as alternatives.

Continuous culture

Continuous culture is a microbiology method in which cells grow in a bioreactor of fixed volume at steady state, with fresh medium added and spent culture removed continuously.

Continuous EEG monitoring

Continuous EEG (cEEG) monitoring records brain electrical activity with synchronized video for hours to weeks in critically ill patients, the reference standard for detecting electrographic seizures.

Continuous erector spinae plane block

The continuous erector spinae plane block is a regional anesthesia technique using a catheter to infuse local anesthetic along the spine for chest and abdominal pain relief.

Continuous glucose monitoring

Continuous glucose monitoring (CGM) is a wearable medical device that measures glucose under the skin every one to five minutes, guiding diabetes treatment with trend data.

Continuous kidney replacement therapy

Continuous kidney replacement therapy (CKRT, historically CRRT) is blood purification run for 24 hours or longer in critically ill patients with acute kidney injury, removing fluid and solutes slowly and continuously.

Continuous passive motion

Continuous passive motion (CPM) is a rehabilitation therapy in which a motorized machine moves a joint through a preset arc without muscular effort, used after joint surgery.

Continuous positive airway pressure

Continuous positive airway pressure (CPAP): machine delivering mild constant air pressure through a mask to keep the airway open during sleep. Introduced by Colin Sullivan in 1981; standard treatment for obstructive sleep apnea, also used in preterm infants.

Continuous renal replacement therapy

Continuous renal replacement therapy (CRRT), or continuous RRT, is a set of dialysis-like filtration techniques run for hours to days in critically ill ICU patients with acute kidney injury.

Continuous suture

A continuous suture is a wound-closure technique using one strand of suture material for a series of stitches, tied at each end, chosen for rapid closure of long wounds.

Contopus

Contopus (pewees) is a genus of tyrant flycatchers established by Cabanis in 1855, with about 14 to 16 American species including the Eastern and Western Wood-Pewees, Greater Pewee, and Near Threatened Olive-sided Flycatcher; perch-hunting flycatchers identified by wingbars, no eye ring, and distinctive songs.

Oct 15, 2026

Contour Next

Contour Next is a family of blood glucose monitoring systems, with meters and test strips made by Ascensia Diabetes Care, introduced in 2012 as the successor to Bayer's CONTOUR meters.

Contraceptive Devices

Contraceptive devices: physical products preventing pregnancy, including copper and hormonal IUDs, implants, condoms, diaphragms, and sterilization devices; effectiveness, WHO MEC/SPR safety guidance, and history from the 1909 Richter ring onward.

Contraceptive implant

Contraceptive implant (Nexplanon, formerly Implanon; predecessor Norplant): a single rod placed under the upper-arm skin releasing etonogestrel for 3 years, over 99% effective at preventing pregnancy but offering no STI protection.

Contract farming

Contract farming: advance agreements between farmers and buyers on production and marketing terms (price, quality, delivery, inputs). Known as outgrower or contract growing; spans colonial-era origins, US broiler tournament pay, and smallholder income effects of 23-54 percent.

Contract manufacturing organization

Contract manufacturing organization (CMO): a company making drugs or ingredients for sponsors under contract; CDMOs add development services. Key facts: late-1990s takeoff, 1997 FDA BLA change, 10-15% annual growth since 2013, 80% of emerging biopharma drugs CDMO-made.

Contract Services

Contract services, or contracting out, are services purchased from external providers under agreements specifying quantity, quality, price, and period; widely used in health care for support, clinical, and hospital management services, with mixed documented effects.

Contracted socket

Contracted socket (eye), also called socket contracture after enucleation or evisceration: shrinkage of anophthalmic orbital tissue with shallow fornices that prevents retention of an ocular prosthesis; graded by severity and treated with grafts, implants, and flaps.