72,234 articles
Cuttlefish camouflage and signaling
Cuttlefish camouflage and signaling is the rapid change of skin color and pattern cuttlefish use to hide from predators, signal to mates and rivals, and disguise hunting strikes.
Cuttlefish in research and aquaria
Cuttlefish in research and aquaria describes how cuttlefish serve as laboratory model organisms for camouflage and cognition and as popular display animals in public aquaria.
Cutworm
Cutworm, the caterpillar stage of many Noctuidae moth species such as black cutworm (Agrotis ipsilon) and variegated cutworm (Peridroma saucia), cuts seedling stems at the soil line, feeds nocturnally, and is managed by collars, handpicking, tillage, and weed removal.
Cuvier's beaked whale
Cuvier's beaked whale (Ziphius cavirostris, goose-beaked whale), a beaked whale of deep waters worldwide; deepest-diving mammal at 9,816 ft and 222 minutes, IUCN Least Concern, threatened by naval sonar.
Cuvieronius
Cuvieronius, an extinct gomphothere proboscidean genus with spirally twisted, enamel-banded upper tusks; type species C. hyodon ranged from North America to Ecuador, Peru, and Bolivia.
CUX1
CUX1 (cut-like homeobox 1, CDP/CUTL1), gene at 7q22.1 encoding a homeobox transcription factor; haploinsufficient tumor suppressor deleted in −7/del(7q) myeloid malignancies yet overexpressed in advanced cancers.
CV_RCT_M_F trial
CV_RCT_M_F (NCT02747875) was a terminated randomized double-blinded trial at Children's National Health System testing 0.3 mg/kg methadone versus 20 mcg/kg fentanyl before incision in children aged 2 to 7 undergoing cardiac bypass surgery.
CW-2
CW-2 (CW2, CVCL_1151, RCB0778) is a human colon adenocarcinoma cell line from a 55-year-old Japanese woman, CEA-positive, MSI-high, with KRAS Pro140His and TP53 Pro47Pro mutations, used in colorectal cancer and drug screening research.
CWC trial
CWC trial (NCT03429166), Connecting Women to Care, a VA-sponsored randomized trial led by Marylene Cloitre comparing home-based video-delivered STAIR versus present-centered therapy in 161 rural women veterans with military sexual trauma; STAIR produced larger PTSD reductions (d = 1.12 vs 0.78).
CX3CL1
CX3CL1 (fractalkine, neurotactin) is the sole CX3C chemokine, a 373-aa human transmembrane protein at 16q21 whose membrane form mediates leukocyte adhesion and whose ADAM10/17-shed soluble form chemoattracts monocytes, NK, and T cells via CX3CR1.
CX3CR1
CX3CR1 (C-X3-C motif chemokine receptor 1, formerly V28/CMKBRL1) is a human 355-amino-acid seven-transmembrane GPCR on chromosome 3p22.2, the sole receptor for fractalkine CX3CL1, mediating leukocyte adhesion and chemotaxis, an HIV-1 co-receptor, with V249I/T280M polymorphisms linked to atherosclerosis.
CXC chemokine
CXC chemokines (CXCL chemokines) are a chemokine subfamily defined by a Cys-X-Cys motif, split into ELR+ angiogenic neutrophil attractants like CXCL8 and ELR− angiostatic ligands, acting through CXCR1–CXCR7 receptors.
CXC chemokine 16
CXC chemokine 16 (CXCL16), also known as SR-PSOX, is a human chemokine signaling through CXCR6, acting as a membrane-bound scavenger receptor and, when cleaved, a soluble chemoattractant for T cells.
CXCL1
CXCL1 (GRO-alpha, MGSA, NAP-3; mouse homolog KC) is a human ELR+ CXC chemokine gene on chromosome 4q21 encoding a 107-residue secreted neutrophil chemoattractant and angiogenic factor signaling mainly through CXCR2, implicated in inflammation and cancer.
CXCL10
CXCL10 (IP-10, C-X-C motif chemokine ligand 10) is an interferon-inducible CXC chemokine on chromosome 4q21 that binds CXCR3, recruiting and activating T cells and NK cells in infection, autoimmunity, and cancer, and serving as a disease biomarker.
CXCL11
CXCL11, also known as I-TAC or IP-9, is a human chemokine induced by interferon that attracts activated T cells and NK cells by binding the CXCR3 receptor.
CXCL12
CXCL12 (SDF-1), C-X-C motif chemokine ligand 12, a human chemokine gene on 10q11.21; ligand for CXCR4 and ACKR3, driving stem cell homing, immunity, HIV-1 resistance, and cancer metastasis.
CXCL13
CXCL13 (BCA-1, BLC, Angie), C-X-C motif chemokine ligand 13, gene ID 10563, is the most potent B cell chemoattractant; it binds CXCR5 (BLR1), organizes lymphoid follicles, and marks ectopic inflammation, MS, and CNS lymphoma.
CXCL14
CXCL14, also called BRAK, BMAC, KS1, or MIP-2γ, is a non-ELR CXC chemokine cloned in 1999, constitutively expressed in skin and other epithelia, chemoattractant for monocytes, antimicrobial, and still an orphan ligand without a confirmed receptor.
CXCL16
CXCL16 (SR-PSOX), a transmembrane chemokine on chromosome 17p13; membrane form is a scavenger receptor for oxidized LDL, soluble form attracts CD4+/CD8+ T cells via CXCR6; shed by ADAM10/17; implicated in atherosclerosis, kidney disease, and cancer.
CXCL5
CXCL5 (ENA-78, SCYB5), an ELR+ CXC chemokine on chromosome 4q13.3, binds CXCR2 to recruit neutrophils, promote angiogenesis, and drive inflammation and cancer progression.
CXCL8
CXCL8, also called interleukin-8 (IL-8), is a human ELR+ CXC chemokine that recruits and activates neutrophils via CXCR1 and CXCR2. Discovered 1987–1988, gene at 4q13.3; implicated in COPD, asthma, cystic fibrosis, sepsis, and cancer progression.
CXCL9
CXCL9 (MIG, monokine induced by gamma interferon) is an ELR-negative CXC chemokine on human chromosome 4, induced by IFN-γ, that attracts CXCR3-expressing Th1, CD8 T, and NK cells and marks IFN-γ activity in HLH and cancer.
CXCR1
CXCR1 (CD181, IL8RA) is a human class A GPCR on chromosome 2q35, a 350-aa receptor for CXCL8/IL-8 and CXCL6 on neutrophils; it signals via Gαi, drives ROS and degranulation, and has NMR and cryo-EM structures.
CXCR2
CXCR2 (IL8RB, C-X-C chemokine receptor type 2) is a human seven-transmembrane GPCR on neutrophils binding seven ELR+ CXC chemokines including IL-8/CXCL8; it drives neutrophil recruitment in inflammation, cancer, and infection, with antagonists in trials but none approved.
CXCR4
CXCR4 (CD184, LESTR, fusin) is a human seven-transmembrane GPCR, gene at 2q22.1, specific for chemokine CXCL12 (SDF-1); first HIV coreceptor (1996), driver of cancer metastasis, and cause of WHIM syndrome when C-terminally truncated.
CXCR6
CXCR6 (Bonzo, STRL33, TYMSTR) is a seven-transmembrane G protein-coupled chemokine receptor for CXCL16, marking type 1 and tissue-resident memory T cells, with roles in HIV/SIV entry, autoimmune disease, asthma, and cancer immunity.
Cyamopsis
Cyamopsis is a genus of four annual herbaceous Fabaceae legumes native to Africa, Arabia, and the Indian Subcontinent; its cultivated species guar (C. tetragonoloba, cluster bean) yields guar gum, a galactomannan thickener (INS 412) used in food and oil drilling, with India producing about 80% of the crop.
Cyanate hydratase
Cyanate hydratase, also known as cyanase or cyanate lyase, is an enzyme that detoxifies cyanate, decomposing it into ammonia and carbon dioxide in a bicarbonate-dependent reaction.
Cyanazine
Cyanazine (CAS 21725-46-2), a chloro-s-triazine photosystem II inhibitor herbicide introduced in 1972 for corn weed control; phased out in the US by 1999 and not EU-approved; WHO drinking-water guideline 0.6 µg/L.