72,234 articles
D-glyceric aciduria
D-glyceric aciduria (D-glycerate kinase deficiency, D-glyceric acidemia, OMIM 220120) is a rare autosomal recessive GLYCTK-related inborn error of serine and fructose metabolism with highly variable neurological phenotype, first described in 1974.
D-lactate dehydrogenase
D-lactate dehydrogenase (D-LDH, EC 1.1.1.28 and EC 1.1.2.4) is a stereospecific oxidoreductase interconverting pyruvate and D-lactate via NADH or FAD/quinone, found in bacteria, fungi, invertebrates, and as mitochondrial human LDHD, linked to D-lactic acidosis.
D-lysine 5,6-aminomutase beta subunit KamE, N-terminal
D-lysine 5,6-aminomutase beta subunit KamE, N-terminal (IPR028991) is an InterPro protein domain on KamE, the beta subunit of the adenosylcobalamin- and PLP-dependent lysine 5,6-aminomutase (EC 5.4.3.3) of anaerobic bacteria such as Clostridium sticklandii.
D-Ribose
D-Ribose is a five-carbon sugar (C₅H₁₀O₅) that forms the backbone of RNA, is made in the body via the pentose phosphate pathway, and is sold as a supplement.
D-ribose pyranase
D-ribose pyranase (RbsD, EC 5.4.99.62) is a bacterial cytoplasmic enzyme encoded by rbsD that interconverts beta-pyran and beta-furan forms of D-ribose, the first step of bacterial ribose degradation, acting as a homodecamer in the RbsD/FucU family.
D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit GatZ
GatZ (gatZ, UniProt P0C8J8) is the 420-amino-acid non-catalytic subunit of the class II D-tagatose-1,6-bisphosphate aldolase GatYZ in enteric bacteria, required for GatY stability and full activity, and independently a zinc-dependent fructose-6-phosphate 4-epimerase used in tagatose production.
D,L-2-hydroxyglutaric aciduria
D,L-2-hydroxyglutaric aciduria (combined D-2- and L-2-HGA, OMIM 615182) is a rare autosomal recessive SLC25A1 citrate carrier defect causing severe neonatal epileptic encephalopathy with elevated D- and L-2-hydroxyglutarate, usually lethal early in life.
D. Allan Drummond
D. Allan Drummond is a University of Chicago biochemist who studies how cells respond to stress, known for showing that heat-triggered protein condensates are reversible, active, and adaptive.
D. Bernard Amos
D. Bernard Amos, born Dennis Bernard Amos (1923–2003), was an English-born immunogeneticist at Duke University whose work established HLA as the genetic basis of transplant compatibility.
D. Branch Moody
D. Branch Moody, also known as David Branch Moody, is an American immunologist at Harvard Medical School who studies how CD1 proteins show lipids to T cells.
D. Carleton Gajdusek
D. Carleton Gajdusek was an American pediatrician and virologist at the NIH who shared the 1976 Nobel Prize for showing that kuru, a fatal brain disease of the Fore people, was transmissible.
D. Craig Miller
D. Craig Miller, often cited as D.C. Miller, is an American cardiothoracic surgeon who spent his entire 43-year faculty career at Stanford, pioneering endovascular stent-graft repair of thoracic aortic disease.
D. Eugene Redmond
D. Eugene Redmond, Jr., is a neuroscientist and psychiatrist at Yale University known for primate models of Parkinson's disease and for fetal-tissue and stem-cell transplantation research.
D. Gary Gilliland
D. Gary Gilliland is an American physician-scientist who identified genetic drivers of leukemia, including JAK2 mutations, and led Fred Hutchinson Cancer Center from 2015 to 2020.
D. Grahame Hardie
D. Grahame Hardie is a biochemist and Professor of Cellular Signalling at the University of Dundee who first defined and named the cellular energy sensor AMPK in 1987–1988.
D. James Surmeier
D. James Surmeier, also known as D. J. Surmeier, chairs neuroscience at Northwestern's Feinberg School of Medicine; his work on dopamine neuron death in Parkinson's disease has motivated clinical trials.
D. Lansing Taylor
D. Lansing Taylor is an American biophysicist known for fluorescent probes of living cells and for commercializing high-content screening; he is a Distinguished Professor at the University of Pittsburgh working on liver-on-chip systems.
D. Lynn Loriaux
D. Lynn Loriaux (born 1940) is an American physician-scientist in endocrinology who helped introduce the corticotropin-releasing hormone stimulation test and petrosal sinus sampling for diagnosing Cushing's syndrome.
D. M. S. Watson
D. M. S. Watson, born David Meredith Seares Watson, was a British vertebrate paleontologist who held the Jodrell chair at University College London from 1921 to 1951.
D. Mark Hegsted
D. Mark Hegsted, born David Mark Hegsted, was an American Harvard nutrition scientist whose feeding trials produced the Hegsted equation, and who wrote the 1980 Dietary Guidelines for Americans at the USDA.
D. Montgomery Bissell
D. Montgomery Bissell is a physician-scientist and Professor Emeritus of Medicine at UCSF whose 1985 study identified hepatic stellate cells as the liver's principal collagen-producing cells.
D. Neil Granger
D. Neil Granger is an American microvascular physiologist and Boyd Professor Emeritus at LSU Health Shreveport, known for research on ischemia–reperfusion injury and nitric oxide.
D. Nicholas Bateman
David Nicholas Bateman is a British clinical pharmacologist and clinical toxicologist, Professor at the University of Edinburgh, known for work on paracetamol poisoning treatment and poisons services.
D. Ross Camidge
D. Ross Camidge is a British medical oncologist and professor at the University of Colorado, known for leading trials defining first-line treatment of ALK-positive lung cancer.
D. Timothy Bishop
D. Timothy Bishop, also published as Tim Bishop, is a British genetic epidemiologist at the University of Leeds known for mapping the breast cancer genes BRCA1 and BRCA2.
D. Walter Cohen
D. Walter Cohen (1926–2018) was an American periodontist and dental educator who chaired Penn's Department of Periodontics, served as its dental dean, and later led the Medical College of Pennsylvania.
D. Ware Branch
D. Ware Branch is a maternal-fetal medicine specialist and professor of obstetrics and gynecology at the University of Utah, known for research on antiphospholipid syndrome and recurrent pregnancy loss.
D.G. Smyth
D.G. Smyth (Derek G. Smyth) is a biochemist at the National Institute for Medical Research, Mill Hill, known for work on β-endorphin processing and peptide hormone amidation.
D'Arcy Wentworth Thompson
D'Arcy Wentworth Thompson (1860–1948) was a Scottish biologist, classical scholar, and mathematician who pioneered mathematical biology; his book On Growth and Form (1917) explained organic form through physical laws.
D1/D2-hybrid medium spiny neuron
D1/D2-hybrid medium spiny neuron, also called D1/D2-SPN or D1/D2-coexpressing MSN, a striatal projection neuron coexpressing dopamine D1 and D2 receptors with dynorphin and enkephalin; proposed third basal ganglia pathway bearing the D1–D2 receptor heteromer, rare but motor-functionally significant.