72,234 articles
D2 lymphadenectomy
D2 lymphadenectomy is the surgical removal of the stomach's regional lymph nodes to a defined second echelon during gastrectomy for gastric cancer, standard in Japanese guidelines and high-volume European centers.
D283 Med
D283 Med (D283-MED, HTB-185, CVCL_1155) is a human medulloblastoma cell line established in 1985 from peritoneal metastasis of a 6-year-old boy; Group 3/4, MYC-amplified, suspension-aggregating, widely used in metastasis and drug studies.
D3-creatine dilution
D3-creatine dilution (D3Cr) is a stable-isotope test measuring total skeletal muscle mass from one oral dose of deuterated creatine and a urine sample, validated against MRI.
D341 Med
D341 Med (D-341 Med, CVCL_0018, ATCC HTB-187) is a human group 3 medulloblastoma cell line established in 1988 from a 3.5-year-old boy's cerebellar tumor, grown in suspension spheroids with 20-fold c-myc amplification.
D425 Med
D425 Med (CVCL_1275, RRID:CVCL_1275) is a human Group 3 medulloblastoma cell line from a 6-year-old male, MYC- and OTX2-amplified with mutant TP53, used widely in xenograft and therapy studies.
Da Costa's syndrome
Da Costa's syndrome, or irritable heart, soldier's heart, effort syndrome, or neurocirculatory asthenia, is a functional cardiac disorder with effort intolerance, palpitations, and breathlessness described by Jacob Mendes Da Costa in 1871.
Da Jian Zhong Tang
Da Jian Zhong Tang (大建中汤; Japanese daikenchuto, TJ-100) is a classical Chinese warm-interior formula from the Jingui Yaolüe, combining Sichuan pepper, dried ginger, ginseng, and maltose for severe cold abdominal pain, now studied in Japan for postoperative ileus.
Da Qinjiao Tang
大秦艽汤 (Da Qinjiao Tang, Major Gentiana Decoction), a 16-herb classic Chinese formula from Liu Wansu's Suwen Bingji Qi Yi Baoming Ji, dispels wind, clears heat, and nourishes blood for wind-stroke channel patterns; entry 54 of China's classical formula directory.
Da Vinci Surgical System
The da Vinci Surgical System, also known as the da Vinci robot, is a robotic surgery device made by Intuitive Surgical that lets a seated surgeon control instruments through small incisions via a console.
Da‐Neng Wang
Da-Neng Wang is a Chinese-born structural biologist and professor of cell biology at NYU Grossman School of Medicine, known for structures of sodium-coupled transporters like NaCT.
Daan Kromhout
Daan Kromhout (born 1950) is a Dutch cardiovascular epidemiologist who led the Zutphen Study from 1978 and co-chaired the Seven Countries Study, showing fish eating lowers coronary mortality.
Daan M. F. van Aalten
Daan M. F. van Aalten is a Dutch structural biologist, professor at Aarhus University since 2022, known for the first crystal structures of O-GlcNAcase and O-GlcNAc transferase.
DAB2
DAB2 (Disabled-2, DOC-2), gene ID 1601 on chromosome 5p13, encodes a clathrin-associated endocytic adaptor and putative tumor suppressor, lost in most epithelial cancers and required for mouse visceral endoderm development.
DAB2IP
DAB2IP (AIP1, AF9Q34) is a human chromosome 9q33.2 gene encoding a Ras GTPase-activating protein tumor suppressor that inhibits Ras, NF-κB, PI3K/AKT, and other oncogenic pathways; it is frequently silenced by methylation in prostate, breast, colorectal, and lung cancers.
Dabigatran
Dabigatran (Pradaxa), oral direct thrombin inhibitor prodrug dabigatran etexilate; first DOAC, FDA-approved 2010 after RE-LY; 150 mg bid for nonvalvular AF stroke prevention, renal dosing, reversed by idarucizumab.
Dabocemagene autoficel
Dabocemagene autoficel (D-Fi, FCX-007) is Castle Creek Biosciences' investigational ex vivo autologous lentiviral COL7A1 fibroblast gene therapy for dystrophic epidermolysis bullosa wounds, in phase 3 trials NCT04213261 and NCT06892639.
Daboia
Daboia is a genus of five venomous viper species; the Asian Russell's vipers (D. russelii, D. siamensis) cause most snakebite deaths in India and Southeast Asia through procoagulant venom.
Dabrafenib/trametinib regimen
The dabrafenib/trametinib regimen, also called dabrafenib and trametinib, is an oral targeted-therapy combination that blocks the MAPK pathway in BRAF V600-mutated cancers, first FDA-approved for melanoma in 2014.
Dabu Yuanjian
大补元煎 (Da Bu Yuan Jian), a classic Chinese medicine decoction from Zhang Jiebin's Ming-era Jingyue Quanshu; eight herbs led by ginseng and prepared rehmannia, treating severe qi-blood collapse; listed in China's 2023 Ancient Classic Formulas catalogue.
Dabur
Dabur, also known as Dabur India Limited, is an Indian consumer goods company founded by Dr. S. K. Burman in 1884, known for Ayurvedic products like Chyawanprash and Real.
DACAMI trial
DACAMI (NCT05424315) was a 2023 Egyptian dual-center randomized trial testing dapagliflozin 10 mg versus placebo in 100 non-diabetic anterior STEMI patients, showing greater NT-proBNP and LV mass index reductions.
Dacarbazine
Dacarbazine, also known as DTIC, is an intravenous alkylating chemotherapy drug of the triazene class, FDA approved in 1975 and used to treat metastatic melanoma and Hodgkin lymphoma, including as part of the ABVD regimen.
Dacher Keltner
Dacher Keltner is an American social psychologist at the University of California, Berkeley, known for research on compassion, awe, and power, and author of the book Awe.
Dachshund
Dachshund (badger dog, wiener dog): German scent hound bred to hunt badgers underground. Two sizes (standard 16–32 lb, miniature under 11 lb), three coats, prone to IVDD in about one in five dogs.
Daclatasvir
Daclatasvir (Daklinza) is a first-in-class Bristol-Myers Squibb NS5A inhibitor for chronic hepatitis C, used with sofosbuvir; EU approval 2014, withdrawn 2019 commercially, now generic via the Medicines Patent Pool in 112 countries.
Daclizumab
Daclizumab (Zenapax, Zinbryta): humanized anti-CD25 IgG1 antibody blocking the high-affinity IL-2 receptor; first FDA-approved humanized mAb (1997, transplant rejection), later a relapsing MS therapy withdrawn worldwide in March 2018 for liver and brain immune injuries.
Dacrydium
Dacrydium (Sol. ex Lamb., 1806) is a genus of 21 conifer species in Podocarpaceae from Southeast Asia to New Zealand; once a broad genus, it was split, leaving rimu (D. cupressinum) as its best-known member.
Dacrydium cupressinum
Dacrydium cupressinum, rimu or red pine, is New Zealand's endemic podocarp conifer, a 30-50 m dioecious forest tree reaching 1,000 years, once the country's main native timber, IUCN Least Concern.
Dacrymycetes
Dacrymycetes is a class of roughly 110 to 205 gelatinous wood-decaying fungi, mostly brown-rot saprotrophs, known for bright yellow to orange fruiting bodies and a two-spored tuning-fork basidium.
Dacryocystitis
Dacryocystitis, inflammation or infection of the lacrimal sac (tear sac), usually from nasolacrimal duct obstruction. Acute and chronic forms; treated with antibiotics and dacryocystorhinostomy; congenital cases often resolve by age one.