Life and health

Deep dermatophytosis

Deep dermatophytosis, or disseminated granulomatous dermatophytosis, is a rare, life-threatening invasion of dermis and subcutaneous tissue by dermatophytes, mainly Trichophyton rubrum, in CARD9-deficient or immunocompromised patients, with lymph node dissemination and terbinafine or itraconazole treatment.

Deep gluteal syndrome

Deep gluteal syndrome (DGS), formerly piriformis syndrome, is non-discogenic sciatic nerve entrapment in the deep gluteal space causing buttock pain and sciatica; diagnosed by provocation tests and pelvic MRI, treated conservatively first.

Deep hypothermic circulatory arrest

Deep hypothermic circulatory arrest (DHCA) is a cardiac and aortic surgery technique cooling the body to 15–25 °C to stop circulation safely; pioneered by Bigelow, Drew, and Griepp, now often replaced by moderate hypothermia with antegrade cerebral perfusion.

Deep inspiration breath hold

Deep inspiration breath hold (DIBH) is a radiotherapy technique in which patients hold a deep breath during treatment, moving the heart away from the beam to reduce cardiac dose.

Deep learning image reconstruction

Deep learning image reconstruction (DLIR, also DLR) is a medical imaging method using deep neural networks to denoise CT images, enabling lower radiation dose or faster scans.

Deep litter

Deep litter, also called built-up litter, is an animal husbandry method in which bedding is left to accumulate in poultry or livestock housing so microbial decomposition composts manure in place.

Deep mutational scanning

Deep mutational scanning is a bench biology method that measures how up to about 1 million protein mutations affect function, using pooled selection and high-throughput sequencing to score each variant.

Oct 20, 2026

Deep ovarian endometriosis

Deep ovarian endometriosis is deeply infiltrating endometrial disease within the ovary, typically an endometrioma. Also called B5 in ICD-11; scored in rASRM and ENZIAN; diagnosed by transvaginal ultrasound and MRI.

Deep sedation

Deep sedation is a drug-induced state in which a patient cannot be easily aroused but responds purposefully to repeated or painful stimulation, with possible airway support needed.

Deep sequencing

Deep sequencing is a high-throughput DNA sequencing strategy that reads each nucleic acid fragment many times over, letting rare variants be distinguished from errors and immune repertoires be profiled in depth.

Deep subsurface geothermal habitats of hyperthermophilic archaea

Deep subsurface geothermal habitats of hyperthermophilic archaea are below-ground thermal environments, from oceanic crust to deep sediments, where heat-loving archaea live at up to about 120°C.

Deep transcranial magnetic stimulation

Deep transcranial magnetic stimulation (dTMS) is a form of transcranial magnetic stimulation using helmet-like coils that reach deeper brain regions, cleared for depression, OCD, and smoking cessation.

Deep vein thrombosis

Deep vein thrombosis (DVT) is a blood clot in a deep vein of the leg, pelvis, or arm, part of venous thromboembolism; diagnosed by duplex ultrasound, treated with anticoagulants, and complicated by pulmonary embolism and post-thrombotic syndrome.

Deep-sea cnidarian distributions

Deep-sea cnidarian distributions describe where corals, hydroids, anemones, and siphonophores live in the bathyal, abyssal, and hadal zones of the ocean floor and deep water column.

Deep-sea gigantism

Deep-sea gigantism (abyssal gigantism): deep-ocean animals growing larger than shallow-water relatives, seen in giant isopods, giant and colossal squids, and supergiant amphipods; attributed to cold, scarce food, low predation, and oxygen, though not universal across taxa.

Deep-sea scaphopod faunas

Deep-sea scaphopod faunas are the tusk shell assemblages of soft seabeds below roughly 500 m, found worldwide and recorded as deep as 7,000 m in the Sunda Trench.

Deep-water coral

Deep-water coral (deep-sea, cold-water coral): azooxanthellate corals below about 50 m lacking symbiotic algae, feeding on particles in currents; over 3,000 species, reef builders like Lophelia pertusa, threatened mainly by bottom trawling.

Sep 20, 2026

Deepak Bastia

Deepak Bastia is a molecular biologist who studies how DNA replication starts and stops, holding the Donnelly Endowed Chair at the Medical University of South Carolina.

Deepak Chopra (दीपक चोपड़ा)

Deepak Chopra (दीपक चोपड़ा), Indian-born American physician and author of Quantum Healing (1989), coined "quantum healing," founded the Chopra Center and Foundation, wrote 90+ books, and is widely criticized for pseudoscientific use of quantum physics.

Deepak Pandya

Deepak N. Pandya (1932-2020), Indian-American neuroanatomist and physician at Bedford VA and Boston University, mapped primate cortical connections, defined core-belt auditory cortex, and was father of astronaut Sunita Williams.

Sep 20, 2026

Deepak Srivastava

Deepak Srivastava is an American physician-scientist in molecular cardiology who serves as president of the Gladstone Institutes in San Francisco, where his laboratory developed direct cardiac reprogramming, converting connective tissue cells into beating heart muscle cells.

Deer

Deer (family Cervidae) are hoofed mammals distinguished by annually shed, regrown antlers, typically male-only except in reindeer; 47 living species, from Eld's deer to white-tailed deer, with major ecological and management impacts.

Deer farm

Deer farm: commercial husbandry of deer for venison and by-products (hides, velvet, antlers, musk). Established in the Far East for over a century; New Zealand licensed its first farm in 1970; red and fallow deer dominate European farms.

Deer fly

Deer fly (Chrysops spp., family Tabanidae, subfamily Chrysopsinae): small biting tabanid flies, 7-10 mm, mottled wings; females blood-feed, vector tularemia and Loa loa; distinct from larger horse flies (Tabanus).

Deer musk

Deer musk, the dried secretion of the musk gland of male Moschus musk deer, used for 2,000 years in Chinese medicine and perfumery; poaching collapsed populations, now CITES-protected with farmed and artificial substitutes.

DEET

DEET (N,N-diethyl-meta-toluamide) is the most widely used synthetic insect repellent, developed by the U.S. Army in 1946, applied to skin at 5–99% concentrations, repelling mosquitoes and ticks by disrupting olfaction.

Defactinib

Defactinib (VS-6063, PF-04554878, FAKZYNJA) is an ATP-competitive FAK/Pyk2 inhibitor (IC50 0.6 nM). FDA-approved May 2025 with avutometinib for KRAS-mutated recurrent low-grade serous ovarian cancer; failed as mesothelioma monotherapy in COMMAND.

Default mode network

Default mode network (DMN), also called default network, a brain network of medial prefrontal, posterior cingulate, precuneus, angular gyrus, and temporal regions active at rest and during internal thought, suppressed during attention-demanding tasks; named by Raichle et al. 2001.

DEFB1

DEFB1 (HBD-1, BD1) is the human chromosome 8p23.1 gene encoding beta-defensin 1, a constitutively expressed, salt-sensitive epithelial antimicrobial peptide linked to cystic fibrosis, urinary tract defense, and polymorphism-associated caries and periodontitis risk.