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Donna L. Maney

Donna L. Maney is an American neuroendocrinologist at Emory University known for her research on the white-throated sparrow and for reforming how sex differences are studied.

Donna L. Washington

Donna L. Washington is an American internist and health services researcher at UCLA and the VA Greater Los Angeles Healthcare System, elected to the National Academy of Medicine in 2024.

Donna Mancini

Donna M. Mancini is an American heart failure and transplant cardiologist at Mount Sinai, internationally known for exercise testing to time heart transplants and a survival score.

Donnai-Barrow syndrome

Donnai-Barrow syndrome (DBS, FOAR syndrome, OMIM 222448) is an ultra-rare autosomal recessive disorder caused by LRP2 (megalin) variants, marked by hearing loss, high myopia, agenesis of the corpus callosum, and low-molecular-weight proteinuria.

Donnell D. Etzwiler

Donnell D. Etzwiler (1927–2003) was an American pediatric endocrinologist who founded the International Diabetes Center in Minneapolis and pioneered the patient-centered team approach to diabetes care.

Donohue syndrome

Donohue syndrome (leprechaunism) is an extremely rare autosomal recessive INSR-related disorder of extreme insulin resistance, causing intrauterine growth failure, dysmorphic facies, lipoatrophy, organomegaly, and death usually in infancy.

Donor Conception

Donor conception is conceiving a child using sperm, eggs, or embryos donated by someone who does not intend to rear the child and holds no legal parental rights.

Donor hepatectomy

Donor hepatectomy is the surgical removal of part of a living donor's liver for transplantation, balancing a graft large enough for the recipient against a remnant safe for the donor.

Donor insemination

Donor insemination is a fertility treatment using sperm from a donor instead of a partner, used when a male partner has no sperm or there is none.

Donor lymphocyte infusion

Donor lymphocyte infusion (DLI) is a cellular therapy in which lymphocytes from the original stem cell donor are infused after transplantation to treat or prevent relapse of blood cancers.

Donor Selection

Donor selection, also called donor eligibility determination, is the screening and testing of blood, cell, tissue, and organ donors for transmissible disease and health risks, governed by FDA 21 CFR 1271, WHO blood guidelines, and OPTN policies.

Donovan H. Parks

Donovan H. Parks is a Canadian bioinformatician and Senior Researcher at Aalborg University in Denmark, known for CheckM, GTDB-Tk, and leading the Genome Taxonomy Database for over a decade.

Dontscho Kerjaschki

Dontscho Kerjaschki is an Austrian nephropathologist and emeritus professor at the Medical University of Vienna, known for podocyte biology, membranous glomerulonephritis, and discovering lymphangiogenesis in the kidney.

Doodia

Doodia (rasp fern, hacksaw fern) is a genus of Blechnaceae ferns from Asia to Australasia and Hawaii, with scabrous fronds and linear sori; taxonomically merged into Blechnum by some treatments, retained by PPG I.

Doodia aspera

Doodia aspera (prickly rasp fern), Blechnum neohollandicum, a rough-fronded Blechnaceae fern from eastern Australia with pink new growth; probably extinct in New Zealand, 2n = 64.

Doolysaurus

Doolysaurus is a small plant-eating dinosaur from mid-Cretaceous South Korea, named for the cartoon character Dooly; its 2026 description was the first new Korean dinosaur species in 15 years.

Doomscrolling

Doomscrolling (doomsurfing) is compulsive scrolling through negative online news, a term from 2018 Twitter popularized during COVID-19 in 2020; meta-analyses link it to anxiety, depression, and distress, though causality is unestablished.

Doona (organism)

Doona is a genus of 10 resin-bearing dipterocarp tree species endemic to Sri Lanka's wet-zone rainforests, also treated as Shorea sect. Doona; includes the rediscovered Doona ovalifolia.

Door laminoplasty

Door laminoplasty, or open-door laminoplasty, is a posterior cervical spine operation that hinges the laminae open on one side to enlarge the spinal canal and decompress the cord.

Door-to-balloon

Door-to-balloon (D2B) time measures hospital arrival to angioplasty balloon inflation in STEMI. Guideline target 90 minutes (120 for transfers); total ischemic time predicts mortality better.

DOORS syndrome

DOORS syndrome (DOOR syndrome, deafness-onychodystrophy-osteodystrophy-intellectual disability-seizures syndrome, OMIM 220500) is a rare autosomal recessive congenital disorder, often caused by TBC1D24 mutations, with sensorineural deafness, absent nails, short digits, intellectual disability, and infantile seizures.

Dopa-responsive dystonia due to sepiapterin reductase deficiency

Dopa-responsive dystonia due to sepiapterin reductase deficiency (SRD, DYT-SPR, SPR deficiency) is a very rare autosomal recessive neurometabolic disorder caused by SPR gene mutations, with dystonia, oculogyric crises, developmental delay, normal phenylalanine, and dramatic levodopa response; about 43 cases reported.

Dopamine agonist

Dopamine agonist: drug mimicking dopamine at dopamine receptors; includes ergoline (bromocriptine, cabergoline) and non-ergoline (pramipexole, ropinirole) agents; used in Parkinson's disease, RLS, and prolactinoma; risks include impulse control disorders and augmentation.

Dopamine antagonist

A dopamine antagonist, also called an antidopaminergic or dopamine receptor antagonist, is a drug that blocks dopamine by binding to its receptors without activating them, including antipsychotics and antiemetics.

Dopamine beta-hydroxylase

Dopamine beta-hydroxylase (DBH), also called dopamine beta-monooxygenase, is a copper- and ascorbate-dependent enzyme that converts dopamine to norepinephrine, discovered in the 1950s in adrenal chromaffin granules.

Dopamine beta-hydroxylase deficiency

Dopamine beta-hydroxylase deficiency (DBH deficiency, norepinephrine deficiency) is an autosomal recessive disorder of the DBH gene on 9q34 causing absent norepinephrine, dopamine accumulation, severe orthostatic hypotension, and ptosis, treated with droxidopa.

Dopamine D3 receptor

Dopamine D3 receptor (DRD3), a D2-like GPCR cloned in 1990, is limbic-enriched, couples to Gi/o, shares high D2 homology, and is targeted by D3-preferring drugs like cariprazine and PET ligand [11C]-(+)-PHNO.

Dopamine D4 receptor

Dopamine D4 receptor (DRD4): a D2-like G protein-coupled dopamine receptor cloned in 1991, least abundant of five subtypes, distinguished by high clozapine affinity, VNTR polymorphism linked to ADHD and exploratory behavior.

Dopamine hypothesis of schizophrenia

Dopamine hypothesis of schizophrenia: theory that dysregulated dopamine, mesolimbic excess and mesocortical deficit, drives psychotic symptoms; rooted in chlorpromazine, van Rossum 1966, and Seeman's 1975 D2 receptor discovery.

Dopamine receptor

Dopamine receptors (D1–D5; DRD1–DRD5 genes) are G protein-coupled receptors mediating dopamine signaling, split into D1-like (stimulatory) and D2-like (inhibitory) families; targets for Parkinson disease and antipsychotic drugs.