72,234 articles
Elanus
Elanus, the black-shouldered kites, a genus of four Accipitridae raptor species (caeruleus, leucurus, axillaris, scriptus) that hover-hunt rodents in open tropical and subtropical habitats worldwide; the letter-winged kite is the only nocturnal hawk.
Elanus caeruleus
Elanus caeruleus, the black-winged kite (elanio común), a small gray-and-white Accipitridae raptor of Africa, southern Europe, and Asia, hunting rodents by hovering; Least Concern globally, Near Threatened regionally in South Africa.
Elapegademase
Elapegademase (Revcovi, EZN-2279) is a PEGylated recombinant bovine adenosine deaminase given intramuscularly as enzyme replacement therapy for ADA-SCID; FDA-approved October 2018, replacing pegademase (Adagen).
Elaphoglossum
Elaphoglossum (tongue ferns), a Dryopteridaceae fern genus of 600 to 1,100 species with simple fronds and acrostichoid sori, mostly American tropical epiphytes, five molecular clades, Miocene amber fossil.
Elapidae
Elapidae (F. Boie, 1827) is the snake family of cobras, coral snakes, kraits, mambas, taipans, and sea snakes, defined by short fixed front fangs and predominantly neurotoxic venom, with an early Oligocene origin and a late Miocene Australasian radiation.
ELARIS EM-I trial
ELARIS EM-I (M12-665, NCT01620528), AbbVie's phase 3 trial of elagolix 150 mg once daily and 200 mg twice daily versus placebo in 872 women with endometriosis-associated pain; pivotal for Orilissa approval.
ELARIS EM-II trial
ELARIS EM-II (NCT01931670), AbbVie phase 3 trial of elagolix (Orilissa) 150 mg once daily and 200 mg twice daily versus placebo for 6 months in 817 women with endometriosis-associated pain; both doses met dysmenorrhea and nonmenstrual pelvic pain endpoints.
Elasmobranchii
Elasmobranchii, the elasmobranchs or strap-gills, is the cartilaginous fish subclass of sharks, rays, skates, and sawfish, excluding chimaeras; cartilage skeletons, unfused upper jaws, exposed gill slits, and about 37% of species threatened.
Elasmosaurus
Elasmosaurus platyurus, named by Edward Drinker Cope in 1868, is a long-necked plesiosaur from the Campanian Western Interior Seaway of Kansas with 72 neck vertebrae and a neck over 6 m long; its reversed first reconstruction fueled the Bone Wars.
Elasmotherium
Elasmotherium, also called the Giant Unicorn, is an extinct genus of giant Eurasian rhinoceroses whose last species, the Siberian unicorn, survived until at least 39,000 years ago.
Elastase
Elastase: serine proteases that degrade elastin, including pancreatic elastase (digestive enzyme, basis of the fecal elastase-1 test for EPI) and neutrophil elastase (ELANE-encoded, AAT-inhibited, drug target in COPD and ARDS).
Elastic therapeutic tape
Elastic therapeutic tape, or kinesiology tape (Kinesio Tape, developed by Kenzo Kase in 1979), is a stretchy cotton adhesive tape used for pain, swelling, and sports support; systematic reviews find little benefit over sham tape.
Elasticity coefficient
Elasticity coefficient (MCA): local sensitivity of an enzyme reaction rate to a substrate, product, or effector, defined as the relative rate change per relative change in that factor; introduced by Kacser and Burns and Heinrich and Rapoport in 1970s metabolic control analysis.
Elasticity imaging
Elasticity imaging is a family of medical imaging techniques that noninvasively map the stiffness of biological tissue using ultrasound or MRI, used mainly to stage liver fibrosis and characterize tumors.
Elastin
Elastin, from the precursor tropoelastin (ELN gene, chromosome 7), is the cross-linked protein of elastic fibers giving recoil to arteries, lungs, and skin; ~1.1 MPa modulus, desmosine cross-links, no adult synthesis.
Elastoderma
Elastoderma (ORPHA:228240) is an extremely rare acquired skin disorder with localized skin laxity and delayed recoil on elbows, knees, or neck, caused by dermal accumulation of pleomorphic elastic fibers without calcification; cause unknown, no standard therapy.
Elastofibroma dorsi
Elastofibroma dorsi (elastofibroma) is a benign, slow-growing fibroelastic soft-tissue tumor of the infrascapular chest wall, first described by Järvi and Saxén in 1961, common in elderly women, bilateral in about a third of cases, and treated conservatively unless symptomatic.
Elastoma
Elastoma, also called nevus elasticus or juvenile elastoma (Weidman), is a rare connective tissue nevus of dermal elastic fibers causing firm skin-colored to yellowish papules; isolated or with osteopoikilosis as Buschke-Ollendorff syndrome.
Elastosis perforans serpiginosa
Elastosis perforans serpiginosa (EPS) is a rare perforating skin disorder in which abnormal elastic fibers are pushed through the epidermis, forming reddish bumps in snake-like or ring patterns, often on the neck.
ELAVL/Hu proteins
ELAVL/Hu proteins (HuR/ELAVL1, HuB/ELAVL2, HuC/ELAVL3, HuD/ELAVL4) are ARE-binding RNA-recognition-motif proteins that stabilize mRNAs; HuR is ubiquitous and oncogenic when cytoplasmic, the others neuronal.
ELAVL1
ELAVL1 (HuR, Hu antigen R), Gene ID 1994 on human chromosome 19p13.2, is a ubiquitously expressed RNA-binding protein with three RRMs that binds AU-rich elements in mRNA 3' UTRs, stabilizing targets; essential for placental development and implicated in immunity and cancer.
Elazar Zelzer
Elazar Zelzer is an Israeli molecular and developmental biologist, a professor at the Weizmann Institute of Science known for linking skeletal development genetics with mechanosensory neurons.
Elbasvir
Elbasvir (MK-8742) is an HCV NS5A inhibitor used with grazoprevir as Zepatier, a once-daily 50/100 mg tablet for chronic hepatitis C genotypes 1a, 1b, and 4; discontinued in the US market.
Elbow
The elbow (articulatio cubiti) is the compound synovial hinge joint of humerus, radius, and ulna, with three articulations, collateral ligament stabilizers, 0–140° motion, and common injuries including dislocation and epicondylitis.
Elbow arthroplasty
Elbow arthroplasty, also called total elbow arthroplasty, is an orthopedic joint replacement procedure developed for rheumatoid arthritis and now used for unfixable fractures and arthritis.
Elbow arthroscopy
Elbow arthroscopy is a minimally invasive surgical technique that diagnoses and treats conditions inside the elbow joint, including loose-body removal, capsular release, and cartilage debridement.
Elbow Prosthesis
Elbow prosthesis: implant replacing the elbow joint (MeSH D058569, 2011), mainly as total elbow arthroplasty (TEA) in linked or unlinked designs; ~84% survive 10 years; complications include infection, loosening, and ulnar neuropathy.
Eld's deer
Eld's deer (Rucervus eldii), also called brow-antlered deer or thamin, is an endangered Southeast Asian deer with lyre-shaped stag antlers; about 1,500 remain in the wild, declining over 50 percent in 15 years.
Eldecalcitol
Eldecalcitol (ED-71, Edirol) is a Japanese-approved 0.75 μg/day oral vitamin D3 analog for osteoporosis that lowers vertebral fracture risk and raises BMD more than alfacalcidol, with hypercalciuria as its main safety signal.
Elderly care
Elderly care (long-term care for older people) covers personal, social, and medical support for older adults losing capacity. Key facts: informal care is up to 80% of European LTC, 80+ population to triple to 426 million by 2050, and LTC workers average 5 per 100 people 65+ in OECD countries.