72,234 articles
Ellis L. Reinherz
Ellis L. Reinherz is an immunologist, Chief of the Laboratory of Immunobiology at Dana-Farber Cancer Institute and Harvard professor, known for defining human T-cell functional subsets and T-cell receptor structure.
Ellis-Van Creveld syndrome
Ellis-Van Creveld syndrome, also called chondroectodermal dysplasia, is an inherited skeletal disorder causing short limbs, extra fingers, nail and tooth abnormalities, and congenital heart defects.
Elly Tanaka
Elly M. Tanaka, born 1965 in Boston, is an Austrian-based regeneration biologist who studies axolotl limb and spinal cord regeneration and directs IMBA in Vienna since 2024.
Elm
Ulmus (elms), genus of trees in Ulmaceae, Rosales, native to temperate Eurasia, North Africa, and the Americas; 37 accepted species; devastated by Dutch elm disease (Ophiostoma) spread by bark beetles.
Elmer Drew Merrill
Elmer Drew Merrill (1876–1956) was an American botanist who described over 3,000 Far Eastern plant species, built the Manila herbarium, and directed the Arnold Arboretum at Harvard.
Elmidae
Elmidae, riffle beetles, a beetle family (Coleoptera, Byrrhoidea) of small 1-8 mm aquatic beetles whose adults and larvae live underwater in clean flowing streams, breathe via a plastron and abdominal gills, and serve as water quality bioindicators.
ELMO domain
ELMO domain (ELM): conserved domain of unknown function in ELMO/CED-12 family proteins (ELMO1-3, CED-12), scaffolds that bind DOCK180 and activate Rac1 in phagocytosis and cell migration; distinct from the ELMo NLP embedding model.
ELOB
ELOB (TCEB2, elongin B) is a human gene at 16p13.3 encoding the 18 kDa regulatory subunit of the Elongin (SIII) RNA polymerase II elongation factor and the Elongin BC adaptor of CUL2/CUL5 ubiquitin ligases, including VHL and HIV-1 Vif complexes.
Elobixibat
Elobixibat (A3309, GOOFICE) is a first-in-class ileal bile acid transporter inhibitor for chronic constipation, approved in Japan in January 2018; dosed 10 mg daily, it raises colonic bile acids, with abdominal pain and diarrhea as main adverse effects.
ELOC
ELOC (TCEB1, SIII) is a human gene at 8q21.11 encoding elongin C, a 112-residue adaptor in the Elongin/SIII transcription elongation factor and VCB-CR ubiquitin ligase; mutations cause VHL-like disease and ELOC-mutated renal cell carcinoma.
Éloi Marijon
Éloi Marijon is a French cardiologist and electrophysiologist who heads cardiology at Hôpital Européen Georges-Pompidou in Paris and studies sudden cardiac death and rheumatic heart disease.
Eloise (psychiatric hospital)
Eloise, also Wayne County Poorhouse, Eloise Hospital, and Wayne County Psychiatric Hospital, was a Westland, Michigan county complex operating 1832-1979 as poorhouse, asylum, TB sanatorium, and general hospital, peaking at 10,000 patients.
Eloise Giblett
Eloise Giblett (1921–2009) was an American physician and human geneticist who led the Puget Sound Blood Center in Seattle and showed that ADA deficiency causes immunodeficiency.
Elongated labia
Elongated labia, also called labia minora hypertrophy, are inner vaginal folds extending beyond the labia majora; a common nonpathologic anatomical variation, culturally valued in parts of Eastern and Southern Africa, and increasingly targeted by labiaplasty surgery.
Elongation of very long chain fatty acids protein 2
ELOVL2 (Elongation of very long chain fatty acids protein 2) is an endoplasmic reticulum fatty acid elongase acting on C20–C22 polyunsaturated acyl-CoAs; it converts DPA to 24:5n-3, the penultimate precursor of DHA, and is essential for DHA synthesis.
Elongation of very long chain fatty acids protein 4
ELOVL4 (ELOVL fatty acid elongase 4, gene on 6q14) is an ER membrane elongase making very long chain (C28-C38) saturated and polyunsaturated fatty acids in retina, brain, skin, and testes; mutations cause Stargardt-like macular dystrophy, SCA34, and neuro-ichthyosis.
Elongation of very long chain fatty acids protein 6
ELOVL6 (ELOVL fatty acid elongase 6, EC 2.3.1.199) is an ER enzyme elongating C12-C16 saturated and monounsaturated fatty acids, palmitate to stearate; an SREBP-1c/ChREBP-regulated target studied in insulin resistance, NASH, pulmonary fibrosis, skin inflammation, and cancer.
Elongator complex protein 1
ELP1 (formerly IKBKAP, IKAP) encodes elongator complex protein 1, the 1,332-amino-acid scaffold subunit of the six-subunit Elongator tRNA-modification complex on chromosome 9q31; mutations cause familial dysautonomia.
Elongin BC and Polycomb repressive complex 2-associated protein EPOP-like
EPOP-like names proteins homologous to EPOP (C17orf96, esPRC2p48), a mammalian PRC2.1 accessory subunit with an N-terminal BC-box binding Elongin BC and a C-terminal SUZ12-binding region.
Elosulfase alfa
Elosulfase alfa (Vimizim, BioMarin) is recombinant N-acetylgalactosamine-6-sulfatase, weekly IV enzyme replacement therapy for MPS IVA (Morquio A); FDA approved 14 February 2014, improves walking and lung function, boxed warning for anaphylaxis.
Elphidium
Elphidium (de Montfort, 1808) is a genus of benthic foraminifera in family Elphidiidae, order Rotaliida, with planispiral involute tests, retral processes, and canal systems; over 60 morphospecies in estuaries and coastal seas worldwide.
Elranatamab
Elranatamab, sold as Elrexfio, is a humanized bispecific antibody developed by Pfizer that binds BCMA on myeloma cells and CD3 on T cells, approved in 2023 for relapsed multiple myeloma.
Els Goulmy
Els Goulmy, born in 1946, is a Dutch immunologist who identified the first human minor histocompatibility antigens at Leiden, shaping stem cell transplantation; she won the 2002 Spinoza Prize.
Elsa Brändström
Elsa Brändström was a Swedish nurse who organized Red Cross relief for prisoners of war in Siberia during World War I, earning the nickname Angel of Siberia.
Elsa R. Flores
Elsa R. Flores is a cancer biologist and Senior Member in Molecular Oncology at Moffitt Cancer Center in Tampa, Florida, known for establishing p63 and p73 as tumor suppressors.
Elsebet Lund
Elsebet Lund is a molecular biologist at the University of Wisconsin–Madison known for work on ribosomal RNA processing in E. coli and nuclear export of small RNAs.
Eluxadoline
Eluxadoline (Viberzi, Truberzi) is a gut-restricted mixed mu/kappa opioid agonist and delta antagonist approved in 2015 for irritable bowel syndrome with diarrhea; 75-100 mg twice daily, contraindicated without a gallbladder.
Elvin A. Kabat
Elvin A. Kabat (1914–2000) was an American immunochemist at Columbia University who first demonstrated that antibodies are gamma globulins and, with mentor Michael Heidelberger, founded quantitative immunochemistry; his antibody numbering system remains in use.
Elvin C. Stakman
Elvin C. Stakman (1885–1979) was an American plant pathologist at the University of Minnesota who established methods for combating wheat rust fungi and mentored Norman Borlaug.
Elvitegravir
Elvitegravir (EVG, GS-9137, Vitekta) is a once-daily HIV-1 integrase strand transfer inhibitor requiring cobicistat or ritonavir boosting; sold in Stribild (2012) and Genvoya (2015), no longer recommended as initial therapy.