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Life and health

72,234 articles

Elwin E. Fraley

Elwin E. Fraley (1934–2014) was an American urologic surgeon who led the University of Minnesota's urology department from 1969 to 1993, advanced testicular cancer care, and coined "endourology."

Elwood Linney

Elwood Linney is a molecular biologist and Professor Emeritus of Molecular Genetics and Microbiology at the Duke University School of Medicine, known for retinoid signaling research.

Elwood V. Jensen

Elwood V. Jensen (1920–2012) was an American biochemist who discovered the estrogen receptor, the first hormone receptor found, turning it into the basis of modern breast cancer diagnosis and therapy.

Elwyn Elias

Elwyn Elias is a British hepatologist and professor at Queen Elizabeth Hospital Birmingham and the University of Birmingham, known for a 1988 New England Journal of Medicine study reporting poor sulfoxidation in primary biliary cirrhosis.

Elwyn L. Simons

Elwyn L. Simons (1930–2016) was an American vertebrate paleontologist known as the father of modern primate paleontology, who discovered Aegyptopithecus in Egypt's Fayum and led the Duke Primate Center.

Elymus

Elymus (wild rye, wheatgrasses), Linnaeus 1753, is the largest allopolyploid grass genus of tribe Triticeae, Poaceae, with about 150-200 species combining St, H, P, W, and Y genomes, native across the Northern Hemisphere and used for forage, restoration, and breeding germplasm.

ELYS-like domain

ELYS-like domain (InterPro IPR025151, Pfam PF13934): conserved domain in ELYS/AHCTF1/MEL-28, the nucleoporin-kinetochore protein that seeds nuclear pore assembly and binds AT-rich chromatin; also in HOS1.

Elysia (gastropod)

Elysia (Risso, 1818) is a genus of sacoglossan sea slugs, about 101 species, famous for kleptoplasty: species such as E. chlorotica, E. timida, E. crispata, and E. viridis retain functional stolen algal chloroplasts for months.

Elysia chlorotica

Elysia chlorotica is a sacoglossan sea slug that retains functional Vaucheria litorea chloroplasts for roughly a year, surviving months on light and CO2; whole-genome studies find no evidence of algal horizontal gene transfer.

EM-2

EM-2 is a human cell line derived from the bone marrow of a 5-year-old girl with Philadelphia chromosome-positive chronic myeloid leukemia, in second relapse after a bone marrow transplant.

Emactuzumab

Emactuzumab (RG7155) is a humanized anti-CSF1R monoclonal antibody from Roche, now SynOx Therapeutics, that blocks receptor dimerization; it showed 86% ORR in diffuse-type tenosynovial giant cell tumor and is in the phase III TANGENT trial.

Emad N. Eskandar

Emad N. Eskandar is an American neurosurgeon who chairs Neurological Surgery at Montefiore Einstein, having held the Pappas chair at Harvard and Massachusetts General Hospital.

Emad S. Alnemri

Emad S. Alnemri is a molecular biologist at Thomas Jefferson University in Philadelphia who studies apoptosis and inflammatory cell death, known for discovering the AIM2 inflammasome and named a National Academy of Inventors fellow in 2018.

Emad Tajkhorshid

Emad Tajkhorshid is an Iranian-born professor of biochemistry and biophysics at the University of Illinois Urbana-Champaign, best known for molecular dynamics simulations of membrane transport proteins like aquaporins.

Emamectin

Emamectin (emamectin benzoate, MK-244) is a semisynthetic avermectin insecticide introduced in 1997 as Proclaim/Affirm, controlling lepidopteran pests at 8-16 g/ha via glutamate-gated chloride channels, and used against sea lice in salmon.

Emanuel Donchin

Emanuel Donchin (1935–2018) was an Israeli-born psychophysiologist who helped establish event-related brain potentials as a measure of cognition; his Illinois laboratory characterized the P300 and built a P300-based brain-computer interface.

Emanuel Epstein

Emanuel Epstein (1916–2022) was an American plant physiologist at UC Davis, called the father of modern root physiology, who first applied enzyme kinetics to ion uptake in roots.

Emanuel Margoliash

Emanuel Margoliash (1920–2008) was an Egyptian-born biochemist and molecular evolutionist who sequenced cytochrome c and, with Walter Fitch, published the 1967 paper credited with founding molecular phylogenetics.

Emanuel Rubin

Emanuel Rubin (1928–2021) was an American pathologist and chairman emeritus at Thomas Jefferson University whose research proved alcohol itself, not malnutrition, causes liver disease; he founded the textbook Rubin's Pathology.

Emanuel syndrome

Emanuel syndrome, or supernumerary der(22)t(11;22) syndrome (OMIM 609029), a rare chromosomal disorder from 3:1 malsegregation of a balanced t(11;22), causing congenital anomalies, microcephaly, and severe intellectual disability.

Emanuele Di Angelantonio

Emanuele Di Angelantonio, born in Rome in 1974, is an Italian-born professor at Cambridge and director at Human Technopole, known for the INTERVAL trial and SCORE2 risk algorithms.

Emanuele Zucca

Emanuele Zucca, born 1957 in Turin, is a Swiss-Italian medical oncologist and hematologist at IOSI in Bellinzona, co-founder and scientific director of the International Extranodal Lymphoma Study Group since 1998.

Emanuella

Emanuella, also spelled Emuella (a separate trilobite genus), is an extinct Devonian brachiopod genus in family Ambocoeliidae, order Spiriferida, named by Grabau 1925; stationary suspension feeder, 393–359 Ma.

Emapalumab

Emapalumab (Gamifant) is a fully human anti-interferon-gamma monoclonal antibody, the first FDA-approved drug (November 2018) for primary hemophagocytic lymphohistiocytosis refractory to conventional therapy, later expanded to HLH/MAS in Still's disease; the EMA refused European approval.

Emarginata

Emarginata is a Shelley 1896 genus of Muscicapidae chats from southern Africa's Karoo, holding the Karoo, Tractrac, and Sickle-winged Chats, formerly placed in Cercomela.

Emasculation

Emasculation: surgical removal of a male's external genitalia (penis, testes, scrotum), distinct from castration (testes only). Historically created eunuchs in China, Rome, Byzantium; today orchiectomy treats cancer and serves gender-affirming care.

Emavusertib

Emavusertib (CA-4948, AU-4948) is Curis's oral, reversible IRAK4 kinase inhibitor, also active against FLT3 and CLK kinases, in Phase 1/2 TakeAim trials for PCNSL, AML/MDS, and CLL.

EMB-06

EMB-06 (cizutamig, later CND106) is EpimAb's tetravalent BCMA×CD3 FIT-Ig bispecific T-cell engager; Phase 1 in myeloma showed 39.5% ORR, 25% low-grade CRS, no ICANS, and autoimmune development via Vignette Bio and Candid.

Emballonuridae

Emballonuridae, the sac-winged, sheath-tailed, and ghost bats, is a bat family (Gervais 1855) of 13 genera and 47 species in tropical Old and New World habitats, defined by wing scent sacs, a sheathed tail, and insect-hawking flight.

Embalming

Embalming is the chemical preservation of a dead body, today via formaldehyde arterial injection, and in ancient Egypt as mummification with natron and canopic jars; regulated by OSHA formaldehyde limits and the FTC Funeral Rule.