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72,234 articles

Eyeglass prescription

Eyeglass prescription: written spectacle lens order (sphere, cylinder, axis, add, prism, PD) from a refractive eye exam, issued by ophthalmologists or optometrists; distinct from contact lens prescriptions, US release rules, 2024 FTC amendments.

Eyelash

An eyelash is one of the short hairs, usually in 2 to 3 rows along the eyelid margin, that protect the eye and reduce tear evaporation.

Eyelid

Eyelid (palpebra): the thin skin-muscle fold protecting the eye and spreading the tear film. Key facts: thinnest body skin, tarsal plates, meibomian glands, levator and orbicularis muscles, blepharitis, blepharoplasty.

Eyelid avulsion

Eyelid avulsion (ICD-11 NA06.00): traumatic tearing away of part or all of an eyelid, usually from blunt trauma, often with canalicular injury; repaired with stenting, flaps, or grafts.

Eyelid nystagmus

Eyelid nystagmus (lid nystagmus), ICD-11 9C84.6, is a rare slow rhythmic involuntary oscillation of the upper eyelids via the levator palpebrae, first described by Pick in 1916, occurring in convergence-evoked, gaze-evoked, and ocular-nystagmus-coupled forms linked to brainstem or cerebellar lesions.

Eyelid retraction

Eyelid retraction: abnormally high upper or low lower lid position, mostly from thyroid eye disease; causes exposure keratopathy; treated with lubrication, injections, or retractor-lengthening surgery (85% success).

Eyelid sebaceous carcinoma

Eyelid sebaceous carcinoma, also called sebaceous gland carcinoma or meibomian gland carcinoma, is a rare, aggressive eyelid cancer of the oil glands, frequently misdiagnosed and treated mainly with Mohs surgery.

Eyelid trauma

Eyelid trauma is injury to eyelid tissues from blunt or penetrating forces, from black eyes to lacerations, and frequently accompanies eye or orbital injuries needing urgent evaluation.

Eyes-absent phosphatases

Eyes-absent (EYA) phosphatases are a family of four human protein tyrosine phosphatases, EYA1 to EYA4, uniquely using an aspartate nucleophile and a metal ion rather than cysteine.

Eyestalk ablation

Eyestalk ablation is the removal of one or both eyestalks of a female shrimp to speed ovarian maturation, a routine broodstock technique in shrimp hatcheries worldwide.

Eytan Ruppin

Eytan Ruppin is a computational biologist and cancer data scientist known for AI methods predicting individual cancer patients' therapy responses, founding the NCI's Cancer Data Science Laboratory in 2018.

Ezabenlimab

Ezabenlimab (BI 754091) is a humanized IgG4 kappa anti-PD-1 monoclonal antibody from Boehringer Ingelheim that blocks PD-1 binding to PD-L1 and PD-L2; Phase I trials set a 240 mg Q3W dose with 16.2% response rate in solid tumors.

Ezekiel Emanuel

Ezekiel J. Emanuel, American oncologist and bioethicist, founding chair of NIH's Department of Bioethics (1997–2011), Affordable Care Act drafter, Penn Levy University Professor, brother of Rahm Emanuel, author of "Why I Hope to Die at 75."

Ezetimibe

Ezetimibe (Zetia, Ezetrol) is a non-statin cholesterol absorption inhibitor approved by the FDA in 2002. It lowers LDL-C about 25% with statins, modestly reduces cardiovascular events (IMPROVE-IT), and is a guideline-recommended statin add-on.

EZH2

EZH2 (enhancer of zeste homolog 2) is the catalytic histone methyltransferase of PRC2, depositing the H3K27me3 repressive mark; mutated or overexpressed in lymphoma and solid cancers, and the target of tazemetostat, approved 2020 and withdrawn 2026.

Ezo salamander (エゾサンショウウオ)

Ezo salamander (エゾサンショウウオ, Hynobius retardatus), also Hokkaido salamander, is a hynobiid salamander endemic to Hokkaido, Japan, with 40 chromosomes, inducible broad-headed cannibal larvae, IUCN Least Concern but Data Deficient nationally.

Ezogabine

Ezogabine (retigabine; Potiga, Trobalt), a Kv7 potassium channel opener anticonvulsant, was approved in 2011 for adjunctive treatment of adult partial-onset seizures and discontinued in 2017 over blue skin discoloration and retinal pigment changes.

Ezra C. Davidson Jr.

Ezra C. Davidson Jr. was an obstetrician-gynecologist who chaired the department at Charles R. Drew University in Los Angeles and led the American College of Obstetricians and Gynecologists.

Ezra E.W. Cohen

Ezra E.W. Cohen is a Canadian-trained medical oncologist specializing in head and neck cancer, a professor at UC San Diego and Tempus AI's oncology chief medical officer.

Ezrin/radixin/moesin

Ezrin/radixin/moesin (ERM) proteins are three homologous metazoan linkers tethering the actin cytoskeleton to the plasma membrane via a FERM domain, activated by PIP2 binding and threonine phosphorylation, with tissue-specific roles in polarity, immunity, and cancer.

F-actin binding

F-actin binding: association of proteins with filamentous actin, the actin cytoskeleton polymer. Binding sites for eight filament-binding classes mapped by EM plus crystallography; CH-domain ABDs, capping, severing, cross-linking proteins.

F-box domain

F-box domain: roughly 40-amino-acid motif first found in cyclin F that binds SKP1, recruiting one of 69 human F-box proteins into SCF ubiquitin ligase complexes to select substrates for degradation.

F-box protein family

F-box protein family: eukaryotic proteins defined by an F-box motif binding Skp1 in SCF ubiquitin ligases; substrate adaptors in FBXL, FBXW, FBXO classes, ~70 in humans, huge in plants.

F-type ATP synthase

The F-type ATP synthase, or F1Fo ATP synthase, is a two-sector rotary enzyme found in bacteria, mitochondria, and chloroplasts that uses ion gradients to synthesize most cellular ATP.

F. Anthony Greco

F. Anthony Greco is an American medical oncologist in Nashville known for lung cancer and cancer of unknown primary research, and for co-founding the Sarah Cannon Research Institute.

F. Daniel Foley

F. Daniel Foley (1933–2003) was an American pathologist at the US Army Institute of Surgical Research, known for describing herpesvirus infection in burned patients in 1970.

F. Estelle R. Simons

F. Estelle R. Simons, born Frances Estelle Reed Simons, was a Canadian allergist and clinical immunologist at the University of Manitoba known for research on H1-antihistamines in children and anaphylaxis.

F. Henry Ellis

F. Henry Ellis (1920–2011) was an American thoracic surgeon who helped establish cardiac surgery at the Mayo Clinic and became a leading esophageal authority in Boston.

F. John Gennari

F. John Gennari is an American nephrologist at the University of Vermont known for widely cited New England Journal of Medicine reviews on acid-base and electrolyte disorders.

F. Mason Sones

F. Mason Sones was an American physician at the Cleveland Clinic who performed the first selective coronary arteriogram in 1958, developed cine coronary arteriography, and won the 1983 Lasker Award.