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Life and health

72,234 articles

F. Nina Papavasiliou

F. Nina Papavasiliou is a Greek-born immunologist known for work on somatic hypermutation and trypanosome antigenic variation, and head of the Immune Diversity division at DKFZ Heidelberg since 2016.

F. Peter Guengerich

F. Peter Guengerich, born 1949, is an American biochemist at Vanderbilt University known for five decades of work on cytochrome P450 enzymes, which metabolize most drugs.

F. Stephen Hodi Jr.

F. Stephen Hodi Jr. is an American medical oncologist who directs the Melanoma Center at Dana-Farber and led the first human trial of ipilimumab, the first approved checkpoint inhibitor for cancer.

F. Stuart Chapin

F. Stuart Chapin III, known as Terry Chapin, is an American ecosystem ecologist at the University of Alaska Fairbanks who studies arctic carbon and methane cycling.

F. Ulrich Hartl

F. Ulrich Hartl, also Franz-Ulrich Hartl, is a German biochemist at the Max Planck Institute of Biochemistry who established that protein folding inside cells requires molecular chaperones.

F. William Studier

F. William Studier (Frederick William Studier), born 1936, is an American molecular biologist at Brookhaven National Laboratory who developed the widely used T7 protein expression system.

F.H. Ruddle

F.H. Ruddle, known as Frank Ruddle, was a Yale molecular geneticist who pioneered human gene mapping and created the first transgenic mammal, a mouse carrying foreign DNA.

F.R. Salemme

F.R. Salemme (Francis R. Salemme) is a protein crystallographer known for work on cytochromes, β-sheets, and four-α-helical bundles, with affiliations at the University of Arizona and DuPont.

F/St

F/St is an extinct inbred laboratory mouse strain developed by Strong in 1926 at the Bussey Institute, marked by a silver-grey white-blazed coat, high leukemia in older mice, resistance to methylcholanthrene fibrosarcoma, and high X-MLV expression via Bxv1.

F1 hybrid

F1 hybrid: first-generation seed from crossing two uniform inbred parent lines, showing heterosis (hybrid vigour), 15-20% yield edge over open-pollinated varieties, non-uniform F2 offspring, and dominant in maize and vegetable seed markets.

F11

F11, also known as FXI or PTA, is a human gene on chromosome 4 encoding coagulation factor XI, whose defects cause the mild bleeding disorder hemophilia C.

F11R

F11R (JAM-A, CD321), the F11 receptor gene on 1q23.3, encodes an immunoglobulin-superfamily tight junction protein on epithelia, endothelium, leukocytes, and platelets; a reovirus receptor, platelet aggregation inhibitor, and breast cancer therapeutic target.

F12-associated cold autoinflammatory syndrome

FACAS (FXII-associated cold autoinflammatory syndrome) is a rare autosomal dominant autoinflammatory disease caused by F12 p.W268R mutation, causing cold-induced urticarial rash, arthralgia, and IL-1β and bradykinin-mediated inflammation from infancy.

F420-dependent enzymes

F420-dependent enzymes are oxidoreductases that use the deazaflavin cofactor coenzyme F420 for hydride-transfer reactions, driving methanogenesis in archaea and stress survival and drug activation in mycobacteria.

F420, menaquinone cofactor biosynthesis

Cofactor F420 (coenzyme F420, factor 420), a 5-deazaflavin hydride-carrier redox cofactor of archaea and bacteria, and menaquinone (vitamin K2) biosynthesis; F420 built from Fo headgroup plus PEP-derived bridge and polyglutamate tail, distinct from quinone pathways.

F5

F5 (coagulation factor V, proaccelerin) is the human gene on chromosome 1q24.2 encoding factor V, a dual procoagulant and anticoagulant cofactor; its Leiden variant (R506Q) causes activated protein C resistance thrombophilia, and loss-of-function variants cause factor V deficiency bleeding.

F9

F9 (coagulation factor IX, Christmas factor) is the X-linked human gene at Xq27.1 encoding a vitamin K-dependent serine protease zymogen; mutations cause hemophilia B, treatable by replacement and AAV gene therapy.

Faba bean rust

Faba bean rust, caused by Uromyces viciae-fabae, is a major fungal disease of Vicia faba, causing 5-20% typical yield losses and up to 70% in early epidemics; managed with resistant varieties, fungicides, and wheat intercropping.

Fabaceae

Fabaceae (Leguminosae), the legume family: third-largest angiosperm family, ~751 genera and ~19,500 species, six subfamilies, pod fruits, rhizobial nitrogen fixation, and major food crops like soybean, pea, and bean.

Fabales

Fabales is an order of flowering plants with four families: Fabaceae, Polygalaceae, Quillajaceae, and Surianaceae. The legumes alone hold over 95 percent of its more than 20,000 species.

Fabian Theis

Fabian J. Theis, born 1976, is a German computational biologist who directs the Institute of Computational Biology at Helmholtz Munich and is known for the single-cell software Scanpy.

Fabien Zoulim

Fabien Zoulim is a French hepatologist and virologist known for hepatitis B cure research, who heads hepatology at the Hospices Civils de Lyon and co-founded ICE-HBV.

Fabio Benfenati

Fabio Benfenati, born in Bologna in 1954, is an Italian neurophysiologist at the Italian Institute of Technology in Genova known for work on synaptic transmission and light-sensitive neural interfaces.

Fabio Levi

Fabio Levi, born 1949 in Lausanne, is a Swiss cancer epidemiologist who led the Cancer Epidemiology Unit and the Vaud and Neuchâtel cancer registries at the University of Lausanne.

Fábio Rossi

Fábio Rossi, also known as Fabio M.V. Rossi, is an Italian-trained physician-scientist and professor at the University of British Columbia known for stem cell research.

Fabomotizole

Fabomotizole (Afobazol, Афобазол, CM-346) is a non-benzodiazepine benzimidazole anxiolytic registered in Russia in 2006; a sigma-1 receptor agonist also binding NQO2, MAO-A, and melatonin receptors, dosed 30–60 mg/day for anxiety.

FABP5

FABP5 (E-FABP, K-FABP, PA-FABP, mal1) is a 135-aa, 15.2-kDa cytoplasmic fatty acid-binding protein at 8q21.13, first identified in psoriatic keratinocytes, that delivers fatty acids and retinoic acid to PPARβ/δ and is implicated in psoriasis, cancer, diabetes, and pulmonary fibrosis.

FABP7

FABP7 (brain fatty acid-binding protein, BLBP; Gene ID 2173) is a 14–16 kDa fatty acid chaperone of radial glia and astrocytes; DHA binding sends it to the nucleus, and it regulates cortical scaffold stability, sleep, and glioma prognosis.

Fabrice André

Fabrice André, born 1972, is a French medical oncologist specializing in breast cancer, Director of Research at Gustave Roussy since 2020, known for trials of alpelisib and trastuzumab deruxtecan.

Fabrice Barlési

Fabrice Barlési is a French pulmonologist and thoracic oncologist, chief executive of the Gustave Roussy cancer center since 2021, known for the 2016 IFCT molecular profiling study.