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Life and health

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Hepatoportoenterostomy

Hepatoportoenterostomy, also called the Kasai procedure or hepatic portoenterostomy, is an operation that restores bile drainage in infants with biliary atresia by joining a jejunal loop to the liver's porta hepatis.

Hepatopulmonary syndrome

Hepatopulmonary syndrome (HPS): hypoxemia from intrapulmonary vascular dilatations in liver disease or portal hypertension; diagnosed by A-a gradient and contrast echocardiography; cured only by liver transplantation.

Hepatorenal syndrome

Hepatorenal syndrome (HRS) is a form of kidney failure in people with advanced liver disease, most often cirrhosis, in which healthy kidneys stop filtering blood due to severe vessel constriction.

Hepatosplenic T-cell lymphoma

Hepatosplenic T-cell lymphoma (HSTCL), historically hepatosplenic gamma/delta T-cell lymphoma, is a rare aggressive peripheral T-cell lymphoma of the spleen, liver, and bone marrow, usually γδ TCR-positive, with isochromosome 7q, STAT/JAK mutations, and median survival near 12 months.

Hepatotoxicity

Hepatotoxicity, or drug-induced liver injury (DILI), is liver damage from drugs, herbals, or supplements; idiosyncratic DILI causes up to 13% of US acute liver failure and is diagnosed by RUCAM, RECAM, and exclusion.

Hepcidin

Hepcidin: 25-amino-acid hepatic peptide hormone, the master regulator of iron homeostasis via ferroportin internalization; low in iron deficiency, high in inflammation, key to IRIDA diagnosis and drug targeting.

HEPCPR trial

The HEPCPR trial was a randomized study of peginterferon alfa-2a plus ribavirin in 41 HCV/HIV-coinfected patients who had not responded to prior interferon therapy, reporting an intent-to-treat SVR of 21.9%.

HEPES buffer

HEPES buffer is a zwitterionic Good's buffer, introduced by Norman Good and colleagues in 1966, that holds aqueous biological solutions near physiological pH and is widely used in cell culture.

Hepialidae

Hepialidae (ghost moths, swifts), family of primitive Hepialoidea moths; 82 genera, 701 species, cosmopolitan except Madagascar and Antarctica; adults lack a proboscis, larvae tunnel in soil and stems.

Heping Zhang

Heping Zhang is a Chinese American biostatistician who directs Yale's Collaborative Center for Statistics in Science and led the 2014 letrozole trial that changed PCOS infertility treatment.

Heptabarbital

Heptabarbital (Medomin, Heptabarb, CAS 509-86-4) is a withdrawn cycloheptenyl-ethyl barbiturate hypnotic, ATC N05CA11, DDD 0.2 g oral, half-life about 7.6 h, formerly marketed by Geigy for insomnia.

Heptageniidae

Heptageniidae (flatheaded mayflies) is a mayfly family in Ephemeroptera with three subfamilies, 37 genera, and over 606 species, mainly Holarctic and Oriental, with flattened stream-dwelling larvae used as clean-water bioindicators.

Heptamaloxyloglucan

Heptamaloxyloglucan (CAS 870721-81-6), a DP 7 xyloglucan-derived oligosaccharide from apple pomace, is an EU low-risk plant elicitor active substance used on grapevines against frost damage, approved 2023 to 2038.

Heptenophos

Heptenophos (OMS 1845, CAS 23560-59-0) is an obsolete organophosphate insecticide and veterinary ectoparasiticide, an acetylcholinesterase inhibitor with rat oral LD50 96 mg/kg, soil DT50 1.4 days, not approved in the EU.

HER2 testing

HER2 testing is the laboratory measurement of HER2 protein overexpression or ERBB2 gene amplification in tumors, using immunohistochemistry and in situ hybridization, to guide anti-HER2 therapy.

HER2/CEP17 FISH ratio assay

The HER2/CEP17 FISH ratio assay is a dual-probe fluorescence in situ hybridization test measuring HER2 gene signals against chromosome 17 signals to determine breast cancer eligibility for anti-HER2 therapy.

HERA trial

HERA (HERceptin Adjuvant, BIG 1-01, NCT00045032) trial: phase 3 study of 5,102 women with HER2-positive early breast cancer randomized to 1 or 2 years of adjuvant trastuzumab versus observation after chemotherapy; 1 year improved survival, 2 years added none.

Heracleum (plant)

Heracleum, commonly known as hogweed or cow parsnip, is a genus of about 90 herbs in the carrot family native to the temperate Northern Hemisphere, some reaching 18 ft.

Heracleum mantegazzianum

Heracleum mantegazzianum, giant hogweed, is a 5 m tall monocarpic Apiaceae herb native to the Western Greater Caucasus, invasive in Europe and North America, whose furanocoumarin sap causes phototoxic dermatitis.

Heracleum sphondylium

Heracleum sphondylium, common hogweed or cow parsnip, is a native European Apiaceae herb, 0.3-1.5 m tall with blunt leaves and small umbels, only weakly phototoxic, unlike giant hogweed.

Herb

Herb: botanically, a non-woody plant whose stem dies back yearly; in common use, plants used for flavoring, medicine, and perfume. Key facts: fresh-to-dried ratio 3:1, 0 C storage, USD 5.9 billion fresh herb market.

Herbaceous plant

Herbaceous plant: a non-woody vascular plant whose above-ground parts die back seasonally; includes annuals, biennials, and perennials; about half of angiosperm species; lacks secondary growth.

Herbal medicine

Herbal medicine, also known as phytotherapy, is healing that uses plant parts such as roots, leaves, flowers, and seeds to maintain health and treat illness.

Herbal medicine in veterinary practice

Herbal medicine in veterinary practice, also called veterinary phytotherapy, uses medicinal plants to prevent or treat disease in animals, prescribed or supervised by a licensed veterinarian.

Herbario nacional

Herbario Nacional de Costa Rica (CR), the national herbarium of Costa Rica at the Museo Nacional in San José: founded 1887, about 500,000 specimens, roughly 4,500 types, largest herbarium in Central America.

Herbario paul c . standley

Herbario Paul C. Standley (EAP), herbarium of Zamorano's Escuela Agrícola Panamericana in Honduras, founded 1943, renamed 1964; largest Honduran collection, over 200,000 sheets, most type specimens in Central America.

Herbarium jujuy agronomia

Herbarium JUA (Herbario JUA) is the herbarium of the Facultad de Ciencias Agrarias, Universidad Nacional de Jujuy, Argentina, founded April 1981 by Osvaldo Ahumada and Alicia Rotman, holding over 18,000 specimens and the only herbarium in Jujuy province.

Herbarium messanaensis

Herbarium messanaensis (MS) is the University of Messina herbarium, founded 1900, holding about 15,000 vascular plant and algae specimens, with an 8,481-specimen historic Sicilian section and a 17th-century Castelli-attributed volume.

Herbarium UFRO

Herbarium UFRO (UFROH) is the Index Herbariorum-registered herbarium of the Universidad de La Frontera in Temuco, Chile; registered in 2015 with 50 specimens, it vouchers plant and fungal research in the Araucanía Region.

Herbaspirillum

Herbaspirillum: genus of gram-negative, vibrioid Oxalobacteraceae bacteria (Baldani et al. 1986; type species H. seropedicae), nitrogen-fixing endophytes of grasses used as crop inoculants.