72,234 articles
HHEX
HHEX (hematopoietically expressed homeobox; also HEX, PRH) is a human chromosome 10 gene encoding a homeobox transcription factor required for foregut organ, vascular, and blood development and implicated in AML, T-ALL, and type 2 diabetes.
Hiatal hernia
Hiatal hernia (hiatus hernia): the stomach's top bulges through the diaphragm's esophageal hiatus. Very common with age (70% over 70); type 1 sliding form is 95% of cases; treated with PPIs or laparoscopic fundoplication.
Hiatal hernia repair
Hiatal hernia repair is surgery that pulls a stomach herniated through the diaphragm back into the abdomen, narrows the hiatus, and usually adds a fundoplication to restore the antireflux barrier.
Hib vaccine
Hib vaccine, or Haemophilus influenzae type b conjugate vaccine, protects infants against Hib meningitis. Conjugate vaccines licensed since 1987 cut US Hib infection by over 99%; given at 2, 4, 6, and 12–15 months.
Hibernation
Hibernation, or prolonged torpor, is a seasonal state of suppressed metabolism and body temperature in mammals and one bird, with bouts of days to weeks, interbout arousals, metabolic rates as low as 2% of basal, and distinct bear winter sleep.
HIBIC-NSCLC study
HIBIC-NSCLC (NCT06518018) is a retrospective propensity score-matched study at Neijiang Second People's Hospital testing HDR brachytherapy plus immune checkpoint inhibitors and docetaxel as second-line treatment for advanced NSCLC, reporting improved OS and PFS.
Hibiscus
Hibiscus is a genus of about 200–438 species in Malvaceae, tribe Hibisceae, native to tropics and subtropics, known for showy flowers, ornamental and fiber uses, and roselle (H. sabdariffa) tea; molecular studies show the genus is polyphyletic.
Hibiscus 'Kopper King'
Hibiscus 'Kopper King' (Hibiscus moscheutos 'Kopper King') is a Fleming-brothers hardy hibiscus cultivar, PP 10,793, with copper-red foliage and 10-12 inch white-pink red-eyed flowers, hardy to zone 4.
Hibiscus syriacus
Hibiscus syriacus, rose of Sharon or shrub althea, is a deciduous Malvaceae shrub native to southern China and Taiwan, the national flower of South Korea, hardy to USDA zone 5, with white-to-purple summer flowers and many cultivars.
Hiccup
Hiccup (singultus, hiccough): involuntary diaphragm spasm with sudden vocal cord closure producing the "hic" sound. Usually self-limiting; hiccups over 48 hours may indicate GERD, stroke, or tumors; chlorpromazine is the only FDA-approved drug.
HiChIP
HiChIP is a chromatin conformation method that combines ChIP with proximity ligation to map genome-wide interactions for a chosen protein, introduced by Mumbach and colleagues in 2016.
Hick's law
Hick's law, or the Hick–Hyman law, states that choice reaction time rises linearly with the logarithm of the number of alternatives (RT = a + b log2 n). Established by W. E. Hick (1952) and Ray Hyman (1953) from information theory, with roots in Merkel's 1885 experiments; a foundational but debated principle of interface design.
Hickman line
Hickman line, also called Hickman catheter, a tunneled silicone central venous catheter with a Dacron cuff, invented by Robert Hickman in 1979 by enlarging the Broviac catheter for bone marrow transplantation; used for chemotherapy, parenteral nutrition, and blood sampling.
Hickory
Hickory (Carya, Juglandaceae): about 16 hardwood species native to Asia, Central America, and North America, prized for shock-resistant tool-handle wood and oil-rich nuts; European species went extinct in the Ice Age.
HiCM-188 (iPSC-derived cardiomyocytes)
HiCM-188 (人iPSC来源心肌细胞注射液) is HELP Therapeutics' allogeneic iPSC-derived cardiomyocyte injection for severe ischemic heart failure, given during CABG; first iPSC-CM therapy with IND clearance in both China and the US, with HEAL-CHF results published in Nature Medicine.
Hidde Ploegh
Hidde Ploegh, born in 1953, is a Dutch-born immunologist and biochemist known for his analysis of MHC antigen presentation and for developing the sortagging protein-labeling method.
Hiddo J.L. Heerspink
Hiddo J.L. Heerspink, also known as Hiddo Lambers Heerspink, is a Dutch clinical pharmacologist at the University Medical Center Groningen who leads chronic kidney disease drug trials.
HIDEA syndrome
HIDEA syndrome is a rare autosomal recessive neurodevelopmental disorder caused by P4HTM gene variants, first described in 2014 in Finland; fewer than 50 patients worldwide show hypotonia, intellectual disability, and epilepsy.
Hideaki Kato
Hideaki Kato (加藤 英明) is a Japanese structural biologist and professor at the University of Tokyo's RCAST who determines structures of membrane proteins such as channelrhodopsins and GPCRs.
Hidehiko Inagaki
Hidehiko Inagaki is a Japanese systems neuroscientist who leads a research group at the Max Planck Florida Institute for Neuroscience, studying how the brain times actions.
Hidehiko Saito
Hidehiko Saito (齋藤英彦) is a Japanese hematologist, professor emeritus of Nagoya University, known for identifying the Fletcher and Fitzgerald clotting factors and establishing the MEG-01 leukemia cell line.
Hidekazu Tsukamoto
Hidekazu Tsukamoto is an American hepatologist, professor of Pathology and Medicine at USC, who directs the Southern California Research Center for Alcohol-Associated Liver and Pancreatic Diseases.
Hideki Kandori
Hideki Kandori (神取 秀樹) is a Japanese biophysicist at Nagoya Institute of Technology known for microbial rhodopsins and optogenetics, including discovering the sodium-pump rhodopsin KR2.
Hideki Taniguchi
Hideki Taniguchi (谷口 英樹) is a Japanese physician-scientist who heads regenerative medicine at the University of Tokyo, known for creating vascularized human liver tissue from iPS cells in 2013.
Hidenori Ichijo
Hidenori Ichijo (一條秀憲), born in 1958, is a Japanese biochemist known for discovering ASK1 and the ASK family of stress-response enzymes, winning the 2021 Japan Academy Prize.
Hidesaburô Hanafusa
Hidesaburô Hanafusa, known as Saburo (1929–2009), was a Japanese virologist at The Rockefeller University who showed that retroviral cancer genes come from healthy host cells, work honored by the 1982 Lasker Award.
Hideyo Noguchi (野口英世)
Hideyo Noguchi (野口英世, 1876-1928), Japanese bacteriologist at the Rockefeller Institute; proved syphilis spirochete causes neurosyphilis, wrongly claimed Leptospira icteroides causes yellow fever, died of it in Accra, Ghana, 1928; on the 1,000-yen note.
Hideyoshi Harashima
Hideyoshi Harashima (原島 秀吉) is a Japanese pharmaceutical scientist at Hokkaido University who developed the MEND nanocarrier and programmed packaging for delivering DNA, siRNA, and mRNA into cells.
Hideyuki Okano
Hideyuki Okano (岡野栄之, born 1959 in Tokyo) is a Japanese neuroscientist, professor of physiology at Keio University School of Medicine and leader of Japan's Brain/MINDS brain-mapping project.
Hidradenitis suppurativa
Hidradenitis suppurativa (acne inversa) is a chronic inflammatory skin disease causing painful nodules, abscesses, tunnels, and scarring in armpits, groin, and other skin-fold areas, typically starting after puberty, more common in women, and treated with antibiotics, biologics such as adalimumab, and surgery.