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Edgepedia

519,064 articles

TMPRSS6

TMPRSS6 encodes matriptase-2, a liver type II transmembrane serine protease that suppresses hepcidin by cleaving hemojuvelin; mutations cause IRIDA, and variants affect iron status.

TMR angle sensor

A TMR angle sensor is a magnetic position sensor that measures rotation angle over a full 360° using the tunneling magnetoresistance effect, serving automotive steering, industrial equipment, and joysticks.

TMRW Life Sciences

TMRW Life Sciences, formerly Genesis And Bond Inc., is a New York fertility technology company founded in 2018 that automates frozen egg and embryo storage for IVF clinics.

TMS Entertainment (株式会社トムス・エンタテインメント)

TMS Entertainment (株式会社トムス・エンタテインメント), the former Tokyo Movie and Tokyo Movie Shinsha, is a Japanese animation studio in Nakano, Tokyo, owned by SEGA. Known for Lupin the 3rd, Anpanman, and Detective Conan, it absorbed subsidiary Telecom Animation Film in April 2026.

TMS protecting group

The TMS protecting group is the trimethylsilyl group, which temporarily masks alcohol hydroxyls in multi-step synthesis; it is the smallest and most easily removed silyl protecting group.

TMS320

TMS320 is a family of digital signal processors from Texas Instruments, introduced with the TMS32010 in 1982 and now spanning the C2000, C5000, and C6000 platforms.

TMS9918

The TMS9918 is a video display processor introduced by Texas Instruments in the late 1970s to generate color video for home computers and game consoles.

Tmsuk

Tmsuk is a Japanese service-robot manufacturer founded in 2000, originating in Kitakyushu and later based in Kyoto, best known for the Enryu rescue robots and more than 40 robot types.

TMTpro

TMTpro is a family of amine-reactive isobaric tandem mass tag reagents sold by Thermo Fisher Scientific that expands multiplexed proteome quantification to 16 and 18 samples per run.

Tmunity Therapeutics

Tmunity Therapeutics was a clinical-stage Philadelphia biotechnology company developing CAR-T cancer therapies, founded in 2015 by University of Pennsylvania scientists and acquired by Kite Pharma in 2023.

TMX Group

TMX Group Limited is the Canadian holding company owning the Toronto Stock Exchange, TSX Venture Exchange, and Montréal Exchange, formed by the 2008 TSX–Montréal merger.

TMZ

TMZ (Thirty Mile Zone) is an American celebrity news brand: TMZ.com, founded by Harvey Levin in November 2005 by Telepictures and AOL, famous for breaking Michael Jackson's 2009 death, sold to Fox Entertainment in 2021.

TN 2026

TN 2026 (TN 2026: Thanga Natchathiram) is a 2026 Tamil political satire film directed by Umapathy Ramaiah, starring Natty as a film star entering politics; released April 10, 2026, produced by Kannan Ravi.

Tn-seq

Tn-seq is a bacterial genetic method, introduced in 2009, that determines gene essentiality and fitness effects by deep-sequencing the insertion sites of a saturated transposon mutant library.

TNA Genesis (2026)

TNA Genesis 2026 was a TNA wrestling pay-per-view held January 17, 2026, in Garland, Texas, where TNA World Champion Mike Santana defeated Frankie Kazarian in a Texas Death Match.

TNA International Championship

TNA International Championship: secondary men's pro wrestling title in Total Nonstop Action Wrestling, created April 2025 to replace the Digital Media Championship; inaugural champion Steve Maclin; current champion Mustafa Ali (second reign, from August 23, 2026).

TNA Knockouts Television Championship

TNA Knockouts Television Championship, a TNA women's wrestling title announced June 28, 2026 at Slammiversary by Traci Brooks; a 16-woman tournament from July 2, 2026 crowns the inaugural champion, defended only on Impact TV.

TNA Lockdown (2026)

TNA Lockdown 2026, TNA Wrestling's all-steel-cage premium live event, August 23, 2026, Credit Union 1 Arena, Chicago; first Lockdown since 2016, Lethal Lockdown returned, Nemeths won tag titles, Slater won X-Division title and invoked Option C.

TNA Rebellion (2026)

TNA Rebellion 2026, the eighth Rebellion pay-per-view by Total Nonstop Action Wrestling, held April 11, 2026 at the Wolstein Center in Cleveland, Ohio; Mike Santana retained the TNA World Championship against Eddie Edwards, with new tag team and International champions crowned.

TNA Sacrifice (2026)

TNA Sacrifice 2026 was the 17th Sacrifice event by Total Nonstop Action Wrestling, held March 27, 2026 at the Alario Center in New Orleans, Louisiana, streamed on TNA+; Mike Santana retained the TNA World Championship when his main event against Steve Maclin ended in a no contest.

TNB Genco

TNB Genco, formally TNB Power Generation Sdn. Bhd., is the wholly owned power generation subsidiary of Malaysia's Tenaga Nasional Berhad and the largest single generator in Peninsular Malaysia.

TNF inhibitor

TNF inhibitors (anti-TNF drugs, TNF blockers): five FDA-approved biologics (infliximab, adalimumab, etanercept, golimumab, certolizumab pegol) that neutralize TNF-α to treat rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, and ankylosing spondylitis; first approved 1998.

TNF receptor family, RELT

RELT (TNFRSF19L), Receptor Expressed in Lymphoid Tissues, is an orphan TNF receptor superfamily member on chromosome 11q13.4, expressed in lymphoid and hematopoietic tissues, with no known TNFSF ligand, paralogs RELL1 and RELL2, and links to cancer and T cell regulation.

TNF signaling

TNF signaling: pathways activated when TNF-α (tumor necrosis factor alpha) binds TNFR1 or TNFR2, driving NF-κB/MAPK survival, apoptosis via complex II, or RIPK1/RIPK3 necroptosis.

TNFAIP3

TNFAIP3 (A20), gene ID 7128 at 6q23.3, encodes a 790-aa ubiquitin-editing enzyme with OTU deubiquitinase and zinc-finger E3 domains that terminates NF-κB signaling; mutations cause A20 haploinsufficiency and autoimmune disease risk.

TNFAIP6

TNFAIP6 (TSG-6), TNF alpha-induced protein 6, is a human chromosome 2q23.3 gene encoding a secreted 35 kDa hyaluronan-binding protein that catalyzes IαI heavy chain transfer to hyaluronan, is essential for cumulus matrix assembly and female fertility, and modulates inflammation.

TNFRSF10B

TNFRSF10B (DR5, TRAIL-R2, CD262, KILLER) is a human chromosome 8p21.3 gene encoding a TRAIL death receptor that forms the DISC with FADD and caspase-8 to trigger apoptosis; a major anticancer drug target with characterized resistance mechanisms.

TNFRSF11A

TNFRSF11A (RANK, CD265) is a human chromosome 18 gene encoding the RANK TNF receptor, essential for osteoclast formation, lymph node and mammary development; duplications cause FEO and Paget-like disease, loss-of-function causes osteopetrosis.

TNFRSF13B

TNFRSF13B (TACI, CD267) is a human gene on chromosome 17p11.2 encoding a TNF receptor on B cells that binds BAFF and APRIL; biallelic variants cause CVID2, heterozygous variants are risk alleles.

TNFRSF13C

TNFRSF13C (BAFF-R, CD268) is a human chromosome 22q13.2 gene encoding the BAFF receptor, a single-CRD type III TNFRSF protein driving B cell survival via non-canonical NF-κB; loss causes CVID4.