400 articles
B95-8
B95-8 is a cotton-top tamarin (Saguinus oedipus) lymphoblastoid cell line, established in 1972 with EBV from the 883L line, that sheds the B95-8 EBV strain used to immortalize human B cells.
BALB/3T3 clone A31
BALB/3T3 clone A31 (ATCC CCL-163, CVCL_0184) is a contact-inhibited mouse embryo fibroblast line from BALB/c mice, established by Aaronson and Todaro in 1968 and widely used in cell transformation assays for carcinogenicity testing.
BALB/cByJ
BALB/cByJ (BALB Bailey Jackson) is an inbred albino laboratory mouse substrain at The Jackson Laboratory, separated from BALB/cJ in 1935, carrying Acads^del-J, Ahr^b-2, and Cdh23^ahl, less aggressive and more fertile than BALB/cJ.
BB65-RCC
BB65-RCC (CVCL_1078, also BB65 or CAJE) is a human male renal cell carcinoma cell line from the Ludwig Institute Brussels, TP53 p.Arg248Trp, HLA-A*02, used in RCC immunotherapy and DepMap/COSMIC datasets.
BEAS-2B
BEAS-2B (Bronchial Epithelium transformed with Ad12-SV40 2B; ATCC CRL-3588/CRL-9609) is a non-tumorigenic immortalized human bronchial epithelial cell line used widely in pulmonary toxicology and carcinogenesis research.
BJAB
BJAB (BJA-B, CVCL_5711) is an EBV-negative human B-cell lymphoma cell line established in 1975 from a Kenyan 5-year-old girl's Burkitt's lymphoma; the first EBV-negative line of this origin, widely used as an EBV-negative control and infection host.
BL-2
BL-2 (BL2, IARC-BL2, CVCL_1966, DSMZ ACC 625) is an EBV-negative human Burkitt lymphoma B-cell line established in 1979 at IARC Lyon from the bone marrow of a 7-year-old boy, carrying a MYC-IGL fusion; distinct from the BL2 B-cell surface antigen.
BL-60
BL-60 (IARC/BL60, CVCL_7034, DSMZ ACC 953) is a human EBV-positive Burkitt lymphoma B-cell line established in 1984 from a 4-year-old Algerian girl's jaw biopsy, carrying a t(8;22) MYC-IGL fusion and TP53 p.Arg282Trp.
BPH-1
BPH-1 (Benign Prostatic Hyperplasia-1, CVCL_1091) is an SV40 large T antigen-immortalized human prostate epithelial cell line from a 68-year-old BPH patient; non-tumorigenic, AR/PSA negative, aneuploid modal 76.
BS-C-1
BS-C-1 (BSC-1, BSC1, CVCL_0607, ATCC CCL-26) is an African green monkey kidney epithelial cell line established in 1961 by Hopps et al., used for virus detection, SV40 work, and transfection; species later corrected to Chlorocebus pygerythrus.
BT-20
BT-20 (CVCL_0178, ATCC HTB-19) is the first human breast cancer cell line, established in 1958 by Lasfargues and Ozzello from a 74-year-old patient; a triple-negative, basal-like TNBC line used in xenograft and spheroid models.
BT-474
BT-474 (ATCC HTB-20, CVCL_0179) is a human breast cancer cell line from a 1978 invasive ductal carcinoma, triple positive for ER, PR, and HER2; used for trastuzumab research, with resistant derivatives like Clone 5.
BT-549
BT-549 (HTB-122, CVCL_1092), also BT549, is a human triple-negative, claudin-low breast cancer cell line isolated in 1978 from a 72-year-old woman's invasive ductal carcinoma; TP53-mutant, PTEN-deleted, drug-resistant, stemness-high research model.
BxPC-3
BxPC-3 (Biopsy xenograft of Pancreatic Carcinoma line-3; CVCL_0186, ATCC CRL-1687) is a human pancreatic ductal adenocarcinoma cell line established in 1980 from a 61-year-old woman, notable for wild-type KRAS with CDKN2A and SMAD4 deletions and TP53 Y220C.
BY-2
BY-2 (TBY-2, NT-1) is a Nicotiana tabacum cv. Bright Yellow 2 suspension cell line derived around 1968 at Japan Tobacco & Salt; fast-growing, aphidicolin-synchronizable, the standard plant cell model and molecular farming platform.
C-33 A
C-33 A (C33A, CVCL_1094, ATCC HTB-31) is an HPV-negative human cervical squamous cell carcinoma cell line established in 1964, carrying a TP53 Arg273Cys mutation, MSI-high, used widely in cervical cancer drug, metastasis, and omics research.
C-643
C-643 (C643, CVCL_5969) is a human anaplastic thyroid carcinoma cell line from a 76-year-old male, established by Nils-Erik Heldin's Uppsala laboratory; HRAS G13R, TP53 R248Q, TERT promoter mutant, BRAF wild type, doubling time 23 hours.
C2 [Dog mastocytoma]
C2 [Dog mastocytoma], also C2-S (CVCL_1R44), is a female dog cancer cell line from a spontaneous canine mastocytoma, KIT exon 11 48-bp ITD, TP53 and CCND3 mutations, toceranib-sensitive, part of the FACC canine tumor cell line panel.
C2BBe1
C2BBe1 (Caco-2/BBe 1) is a 1988 clone of the Caco-2 colon adenocarcinoma cell line forming a polarized brush-border monolayer, used in drug transport, toxicology, and intestine-on-chip models (ATCC CRL-2102).
C2C12
C2C12 (CVCL_0188) is an immortalized mouse myoblast cell line subcloned from the 1977 C2 line of Yaffe and Saxel; it differentiates into contractile myotubes within 72 hours of serum withdrawal and is a standard model for myogenesis, insulin resistance, and muscle disease modeling.
C6/36
C6/36 (ATCC CRL-1660) is a cloned Aedes albopictus mosquito cell line from larval cells, Dicer-2/RNAi deficient, grown at 28 degrees C, and widely used to isolate and propagate dengue, chikungunya, and other arboviruses.
Ca9-22
Ca9-22 (CVCL_1102, JCRB0625, RCB1976) is a human gingival squamous cell carcinoma cell line established by Horikoshi from a 43-year-old Japanese male; EGF-receptor rich, TP53 p.Arg248Trp, some stocks contaminated with MSK-922.
Caco-2
Caco-2 (CaCo-2, ATCC HTB-37) is a human colon adenocarcinoma cell line that differentiates into enterocyte-like monolayers, the standard in vitro model for intestinal drug permeability and oral absorption screening.
CADO-ES1
CADO-ES1 (CADO-ES-1, Center for Adult Diseases Osaka-Ewing Sarcoma 1) is a human Ewing sarcoma cell line established in 1991 from a 19-year-old Japanese woman's pleural effusion, carrying EWSR1-ERG rather than EWSR1-FLI1, with homozygous CDKN2A deletion.
Caki-1
Caki-1 (ATCC HTB-46, CVCL_0234) is a human clear cell renal cell carcinoma cell line established in 1971 from a skin metastasis in a 49-year-old man by Fogh and Trempe at Sloan Kettering; wildtype VHL, metastatic ccRCC model.
Caki-2
Caki-2 (ATCC HTB-47, CVCL_0235) is a human renal cell carcinoma cell line established in 1971 from a 69-year-old man; originally labeled clear cell RCC, it is now classified as papillary RCC.
CAL-27
CAL-27 (CVCL_1107, ATCC CRL-2095) is a human tongue cancer cell line established in 1982 by Gioanni in Nice from a 56-year-old man, widely used in oral squamous cell carcinoma research and reclassified as adenosquamous carcinoma.
Calu-3
Calu-3 (ATCC HTB-55) is a human bronchial adenocarcinoma cell line from a 25-year-old male, used as an airway epithelium model for drug transport, barrier, toxicology, and SARS-CoV-2 studies.
Calu-6
Calu-6 is a human non-small cell lung cancer cell line with a KRAS mutation, established at Memorial Sloan Kettering and used widely in cancer drug screening.
CAMA-1
CAMA-1 (ATCC HTB-21, RRID CVCL_1115) is a luminal-type, ER/PR-positive, HER2-negative human breast cancer cell line established in 1975 by Jorgen Fogh from a pleural effusion, estrogen-dependent, with CDH1, PTEN, and TP53 mutations.