400 articles
Ex vivo culture
Ex vivo culture is a bench biology technique in which cells or tissues removed from a living organism are grown outside the body under controlled laboratory conditions.
Explant culture
Explant culture is a cell culture method in which a tissue fragment is placed in growth medium, either to derive primary cells or to preserve tissue architecture.
FaDu
FaDu (CVCL_1218, ATCC HTB-43) is a human hypopharyngeal squamous cell carcinoma cell line established in 1968 from a 56-year-old male patient from Calcutta, India; a standard HNSCC model with CDKN2A and TP53 mutations used in cisplatin, radiation, and 3D culture studies.
Farage
Farage (CVCL_3302, ATCC CRL-2630) is a human EBV-positive B lymphocyte cancer cell line established in 1990 from a 70-year-old woman with diffuse large B-cell lymphoma; it produces no immunoglobulin and is a PMBL-related research model.
Foreskin fibroblast
Foreskin fibroblast, also called human foreskin fibroblast (HFF, FSK) or the BJ line ATCC CRL-2522: primary dermal fibroblasts from neonatal foreskin, used in toxicology, aging, and tissue engineering research; BJ-5ta is the hTERT-immortalized derivative.
FRTL-5
FRTL-5 (FRTL5, Fischer rat thyroid line 5) is a clonal rat thyroid follicular cell line from Fischer 344 rats, TSH-dependent, iodide-concentrating, used in TSH and Graves' autoantibody bioassays; ATCC CRL-8305.
FTC-133
FTC-133 (FTC133, CVCL_1219) is a human follicular thyroid carcinoma cell line from a 42-year-old male, TP53 and PTEN mutant, near-homozygous genome, PAX8/TTF-1 positive, and flown in space on Shenzhou-8 and the ISS.
G-292 clone A141B1
G-292 clone A141B1 (CVCL_2909, ATCC CRL-1423) is a human osteosarcoma cell line from the bone of a 9-year-old White female, fibroblast-like, with a DAXX-KIFC3 fusion, used in bone cancer and drug screening research.
G-361
G-361 (G361; CVCL_1220; ATCC CRL-1424) is a human malignant melanoma cell line from a 31-year-old male's skin, BRAF V600E-mutant, p53 wild-type, used in toxicology, drug-response, and 3D skin model research.
G-401
G-401 (G401, CVCL_0270, ATCC CRL-1441) is a human kidney cancer cell line established in 1975 from a 3-month-old male, long misclassified as Wilms tumor but reclassified in 1993 as rhabdoid tumor of the kidney with homozygous SMARCB1 deletion.
G-402
G-402 (G402, ATCC CRL-1440, Cellosaurus CVCL_1221) is a human epithelial-like kidney cancer cell line from a 9-month-old female, deposited by PT Peebles; hyperdiploid (modal 47), McCoy's 5a culture, used in renal cancer and DepMap research.
GI-1
GI-1, also written GI1, is a permanent human cancer cell line established in 1992 from a gliosarcoma of the brain, a tumor with both glial and connective-tissue components, at Kyoto University.
GLC-4
GLC-4 (CVCL_0279, GLC4) is a human small cell lung carcinoma cell line from a male pleural effusion metastasis, TP53-mutant, parent of drug-resistant sublines GLC4/ADR, GLC4-CDDP, and GLC4-MITO used in multidrug resistance research.
GM00130
GM00130 (CVCL_7274, also GM17201) is an EBV-transformed human B-lymphocyte cell line from a 25-year-old Caucasian male, a Coriell NIGMS GeT-RM reference material carrying CFTR 4375-36delT and the CYP2C19*2 allele.
GM01650
GM01650 (RRID:CVCL_7328) is a finite human skin fibroblast cell line from a 37-year-old Caucasian woman, held in Coriell's NIGMS Apparently Healthy Collection and used as an unaffected control in genetic disease studies.
GM12878
GM12878 (NA12878) is an EBV-immortalized human lymphoblastoid B cell line from a female HapMap donor of European ancestry, a Coriell-distributed ENCODE Tier 1 line and Genome in a Bottle reference standard for sequencing calibration.
GOTO
GOTO (CVCL_1234, JCRB0612) is a human neuroblastoma cell line established in 1979 from an adrenal tumor of a Japanese male infant; fibroblast-like, ~48-hour doubling, NRAS Q61L mutant, used in differentiation, radiation, and drug studies.
HaCaT
HaCaT (CVCL_0038) is a spontaneously immortalized, aneuploid, nontumorigenic human keratinocyte cell line from adult back skin, established 1988 by Boukamp et al.; widely used skin biology and toxicology model with mutant TP53.
HBL-100
HBL-100 (CVCL_4362) is a human epithelial cell line established from breast milk, carrying tandemly integrated SV40 genomes and a Y chromosome; it is ICLAC-registered as misidentified and used as a breast epithelial model.
HCC1806
HCC1806 is a human breast cancer cell line established in 1995 from a 60-year-old Black woman with squamous breast carcinoma, serving as a widely used model for triple-negative breast cancer.
HCC1937
HCC1937 (HCC-1937, CVCL_0290, ATCC CRL-2336) is a triple-negative, basal-like human breast cancer cell line established in 1995, homozygous for the BRCA1 5382insC mutation, with TP53 mutation and homozygous PTEN deletion, used to study BRCA1 and DNA repair.
HCC1954
HCC1954 (ATCC CRL-2338) is a human breast cancer cell line from a 1995 grade 3 invasive ductal carcinoma; HER2-overexpressing, ER/PR-negative, trastuzumab-resistant, used to test anti-HER2 drugs and antibody-drug conjugates.
HCT 116
HCT 116 (HCT116, HCT-116), a human colorectal carcinoma cell line from a male colon cancer patient, established 1981 by Brattain; MSI-high, KRAS G13D, wild-type TP53, ATCC CCL-247, NCI-60 member.
HCT 15
HCT-15 (HCT 15, CVCL_0292, ATCC CCL-225) is a human colorectal adenocarcinoma cell line from a male Dukes C patient, MSI-high, KRAS G13D, quasidiploid, genetically identical in origin to DLD-1, HCT-8, and HRT-18.
HCT 8
HCT 8 (HCT-8, HRT-18) is a human colorectal adenocarcinoma cell line from a 67-year-old male, MSI-positive with APC, KRAS G13D, and PIK3CA mutations, tumorigenic in nude mice, and genetically identical to DLD-1, HCT-15, and HRT-18.
HEC-1
HEC-1 (HEC1, Human Endometrial Cancer-1) is the first human endometrial adenocarcinoma cell line, established in 1968 from a 71-year-old woman; its MMR-deficient, MSI-high sublines HEC-1-A and HEC-1-B carry KRAS G12D and TP53 R248Q.
HEC-1-A
HEC-1-A (also HEC1A, CVCL_0293, ATCC HTB-112) is a human endometrial adenocarcinoma cell line established in 1968 from a 71-year-old Japanese woman, parent of HEC-1-B; MSI-positive, KRAS-mutant, diploid, low estrogen sensitivity.
HEC-1-B
HEC-1-B (HEC1B, CVCL_0294, ATCC HTB-113) is a tetraploid human type II endometrial adenocarcinoma cell line established in 1968 from a 71-year-old Japanese woman as a subline of HEC-1, with KRAS G12D, TP53 R248Q, MSI, and low ER/PR.
HeLa S3
HeLa S3 (ATCC CCL-2.2, Cellosaurus CVCL_0058) is a 1955 single-cell clone of the HeLa cervical cancer line, cloned by Puck, Marcus, and Cieciura; it carries HPV-18 and can be adapted to suspension culture.
Hep 3B2.1-7
Hep 3B2.1-7 (Hep3B, ATCC HB-8064, CVCL_0326) is a human hepatocellular carcinoma cell line from an 8-year-old boy, established 1976, HBV genome-integrated, AXIN1/RB1 mutated, second most used HCC line after HepG2.