400 articles
HEp-2
HEp-2 (H.Ep.-2, CVCL_1906, ICLAC-00007) is a human cancer cell line described in 1954 as laryngeal carcinoma but shown in 1967 to be a HeLa derivative; still widely used for ANA immunofluorescence testing and virus culture.
HGC-27
HGC-27 (CVCL_1279, ECACC 94042256) is a human gastric cancer cell line established in 1976 from a metastatic lymph node of a Japanese patient with undifferentiated carcinoma; mucin-producing, adherent, TP53/PIK3CA-mutant, highly invasive.
HL-60 (HL60)
HL-60 (HL60, Human Leukemia-60) is a human promyelocytic leukemia cell line established in 1977 from a 36-year-old woman's peripheral blood, later classified FAB-M2 AML; a standard model for myeloid differentiation and neutrophil research.
HPAF-II
HPAF-II, also written HPAF-2, is a well-differentiated human pancreatic ductal adenocarcinoma cell line established from the ascites of a 44-year-old man, cataloged as ATCC CRL-1997.
Hs 294T
Hs 294T (HS294T, CVCL_0331, ATCC HTB-140) is a human metastatic melanoma cell line from a lymph node metastasis, BRAF V600E and TERT promoter mutant, used in drug-response and resistance research.
Hs 578T
Hs 578T (ATCC HTB-126, CVCL_0332) is a human triple-negative, basal-like breast cancer cell line derived in 1977 from a 74-year-old patient, syngeneic with Hs 578Bst, carrying an H-ras codon 12 mutation and a hypotriploid karyotype.
Hs 675.T
Hs 675.T (Hs675T, CVCL_0836, ATCC CRL-7400) is a human colon-derived fibroblast cell line, male Caucasian donor, originally misclassified as colorectal carcinoma; doubling time 6-7 days, DMEM culture, documented STR profile.
Hs 700T
Hs 700T (HS700T, CVCL_0858, ATCC HTB-147) is a human pancreatic ductal adenocarcinoma cell line from a 61-year-old man's pelvic metastasis, hypertetraploid, TP53 p.Arg249Met, doubling time 4-5 days.
Hs 746.T
Hs 746.T (Hs746T, CVCL_0333, ATCC HTB-135) is a human diffuse-type gastric adenocarcinoma cell line established in 1973 from a skeletal muscle metastasis, MET-amplified with a c-Met exon 14 splice mutation, used in MET-inhibitor drug testing.
Hs 766T
Hs 766T (Hs-766T, HS766T, CVCL_0334, ATCC HTB-134) is a human pancreatic adenocarcinoma cell line isolated in 1973 from a lymph node metastasis, carrying homozygous KRAS Q61H and SMAD4 deletion, gemcitabine-resistant, with a normoid gene expression profile.
HSC-2
HSC-2 (HSC2, CVCL_1287, JCRB0622) is a well-differentiated human oral squamous cell carcinoma cell line established in 1989 in Japan from a 69-year-old man, carrying PIK3CA His1047Arg and TP53 splice mutations, non-invasive, and used in drug-screening panels.
HSC-3
HSC-3 (HSC3, JCRB0623, CVCL_1288) is a human oral squamous carcinoma cell line established in 1989 from a 64-year-old Japanese man's tongue cancer, derived from a cervical lymph node metastasis, with high metastatic potential and wide use in OSCC research.
HSC-4
HSC-4 (HSC4, CVCL_1289, JCRB0624) is a human tongue squamous cell carcinoma cell line established in 1989 from a 64-year-old Japanese man's cervical lymph node metastasis, used in over 150 OSCC studies.
HSG
HSG (Human Salivary Gland, CVCL_2517) is a human cancer cell line established in 1981 from an irradiated submandibular salivary gland but shown by STR profiling to be a HeLa derivative; ICLAC-00313, distinct from the HGS1-4 ovarian series.
HT-1080
HT-1080 (HT1080, CVCL_0317, ATCC CCL-121) is a human fibrosarcoma cancer cell line established in 1972 from a 35-year-old man; NRAS-mutant, IDH1 R132C, used in sarcoma research, 3D migration studies, and Shire therapeutic protein manufacturing.
HT-1376
HT-1376 (HT1376, CVCL_1292) is a human bladder transitional cell carcinoma cell line established in 1977 from a 58-year-old woman, near-tetraploid, with RB1, TP53, TERT promoter, and PTEN alterations, used in muscle-invasive bladder cancer research.
HT-29
HT-29 (ATCC HTB-38, CVCL_0320) is a human colorectal adenocarcinoma cell line established in 1964 by J. Fogh from a 44-year-old woman's colon tumor; adherent, enterocyte-like, drug-sensitive, and widely used in cancer, GI barrier, and CRISPR screening research.
HT-3
HT-3 is a human cervical carcinoma cell line established in 1963 by Jorgen Fogh at Sloan Kettering from a metastatic lymph node, long used as an HPV-negative comparator.
Huh-7
Huh-7 (HuH-7, JTC-39, CVCL_0336) is a human hepatoma cell line established in 1982 from a 57-year-old Japanese man's hepatocellular carcinoma; with derivatives Huh7.5 and Huh7.5.1 it is the standard host for hepatitis C virus culture and a model for liver metabolism and cancer.
IGROV-1
IGROV-1 (IGROV1, CVCL_1304) is a human ovarian cancer cell line established in 1985 from a stage III ovarian adenocarcinoma; an NCI-60 member, hypermutated, endometrioid-like, widely used in drug screening.
IM-9
IM-9 (GM04680, ATCC CCL-159) is a human cell line established in 1967 from a multiple myeloma patient but actually an EBV-transformed B-lymphoblastoid line, CD38-negative, near-diploid, used widely in receptor and B-cell research.
IMR-32
IMR-32 (ATCC CCL-127, CVCL_0346) is a continuous human neuroblastoma cell line established in 1967 from a 13-month-old boy, hyperdiploid, MYCN-amplified with 1p deletion, and a standard model of high-risk neuroblastoma.
IMR-90
IMR-90 (Institute for Medical Research-90), ATCC CCL-186, is a finite human fetal lung diploid fibroblast cell line derived in 1975 from a 16-week female fetus for the NIA Aging Cell Repository, a standard model for cellular aging and senescence.
Intestine 407
Intestine 407 (INT 407, Henle-407), a human epithelial cell line established in 1955 as embryonic intestinal tissue but actually a HeLa cervical cancer derivative, ICLAC-00008, used in about 1,400 papers as normal intestine.
IPEC-J2
IPEC-J2 (Intestinal Porcine Epithelial Cell line-J2), a non-transformed porcine jejunal enterocyte line isolated in 1989 by Helen Berschneider; used for intestinal barrier, host-pathogen, probiotic, and nutrition studies, with high TEER in FBS culture.
Ishikawa
Ishikawa, or Ishikawa cells, is a human endometrial adenocarcinoma cell line established by Masato Nishida in 1980 and widely used as a model of type I endometrial cancer.
J-111
J-111 (CVCL_2965, JCRB0073) is a human cell line established in 1955 as acute monocytic leukemia but shown to be a HeLa derivative (ICLAC-00009, HPV18-positive); it was flown on the ISS to study microgravity effects on monocyte motility.
J82
J82 (CVCL_0359, ATCC HTB-1) is a human bladder transitional cell carcinoma cell line from a 58-year-old Swedish male donor, TP53/PTEN/RB1-mutant, with a documented historical T24 cross-contamination issue.
JK-1
JK-1 (CVCL_2079, DSMZ ACC 347) is a human chronic myeloid leukemia cell line established in 1987 from a shoulder-tumor biopsy in erythroid blast crisis; BCR-ABL1 b2a2-positive, it spontaneously differentiates to hemoglobin-producing red cells.
Jurkat
Jurkat (CVCL_0065) is an immortalized human T-lymphocyte leukemia cell line from a 14-year-old boy with T-cell acute lymphoblastic leukemia, the standard model for TCR signaling, HIV studies, and CAR-T testing, with known PTEN, MSH2, and MSH6 defects.