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Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Bundesgesundheitsblatt – Gesundheitsforschung – Gesundheitsschutz is a monthly German public health journal edited at the Robert Koch Institute, published by Springer since 1999, ISSN 1436-9990/1437-1588, Impact Factor 1.6 (2025).
Bundibugyo virus disease
Bundibugyo virus disease (BVD), also called Bundibugyo Ebola, is severe Ebola disease caused by Orthoebolavirus bundibugyoense (BDBV); incubation 2–21 days, no licensed vaccine or treatment, and the 2026 DRC outbreak is the largest recorded, with a 48% case fatality ratio.
Bundle branch block
Bundle branch block (BBB), left (LBBB) or right (RBBB), is a delay or block in the conduction pathway to one ventricle, causing wide QRS on ECG; LBBB signals heart disease and raises heart failure risk (RR 3.44), while management spans pacemakers, CRT, and conduction system pacing.
Bundle branches (heart)
The bundle branches are the two divisions of the heart's conduction system that carry the cardiac impulse from the bundle of His to the left and right ventricles.
Bundle of His
Bundle of His (atrioventricular bundle), discovered by Wilhelm His Jr. in 1893, is the 1.8 cm cardiac conduction strand linking the AV node to the bundle branches; target of His bundle pacing, now compared with left bundle branch pacing.
Bunion
Bunion (hallux valgus): bony bump at the big toe joint from progressive toe drift; affects about 19% of people, mostly women; treated first with footwear and splints, then osteotomy surgery with an 18.5% complication rate.
Bunionectomy
A bunionectomy is an operation that corrects hallux valgus by removing the bunion's bony bump and realigning the great-toe joint to relieve pain, with more than 150 described techniques.
Buntanetap
Buntanetap (Posiphen, ANVS-401), Annovis Bio's oral translation inhibitor of APP, tau, and alpha-synuclein, in Phase 3 for early Alzheimer's (NCT06709014) and Parkinson's disease; investigational, not FDA approved.
Buparlisib
Buparlisib (BKM120), Novartis oral pan-class I PI3K inhibitor; phase 3 BELLE-2/3 showed PFS benefit with fulvestrant in HR+/HER2- breast cancer but limited by rash, hyperglycemia, transaminase toxicity.
Bupivacaine
Bupivacaine (Marcaine, Sensorcaine) is a long-acting amide local anesthetic synthesized in 1957 and marketed in 1965, used for nerve, epidural, and obstetrical blocks; known for potent but cardiotoxic profile versus its S-enantiomers ropivacaine and levobupivacaine.
Buprenorphine
Buprenorphine (Suboxone, Subutex, Sublocade, Brixadi, Butrans): semi-synthetic thebaine-derived Schedule III partial mu-opioid agonist, 20-30x morphine potency, with ceiling on respiratory depression; treats opioid use disorder and pain.
Buprenorphine/naloxone
Buprenorphine/naloxone (Suboxone) is a sublingual combination medication for opioid use disorder, FDA-approved October 8, 2002; naloxone deters injection misuse, and methadone retains more patients but causes more serious adverse events.
Bupropion
Bupropion (Wellbutrin, Zyban) is an aminoketone antidepressant inhibiting norepinephrine and dopamine reuptake with no serotonergic activity, used for MDD, seasonal affective disorder prevention, and smoking cessation; seizure risk is dose-related.
Buried penis
Buried penis, also called concealed or hidden penis, is a normal-sized penis covered by prepubic skin or fat. Covers congenital and adult acquired forms, causes such as obesity and lichen sclerosis, and surgical outcomes.
Burkitt lymphoma
Burkitt lymphoma, an aggressive MYC-translocated germinal-center B-cell non-Hodgkin lymphoma (endemic, sporadic, immunodeficiency-associated variants), highly curable with intensive chemoimmunotherapy, EBV- and malaria-linked in endemic Africa.
Burn
Burn (injury): tissue damage from heat, radiation, electricity, friction, or chemicals; classified by depth and %TBSA; ~180,000 deaths yearly; treated with cooling, fluids, grafts.
Burn Units
A burn unit is a specialized hospital facility providing intensive care for burn patients, built around a multidisciplinary team for wound care, surgery, and rehabilitation.
Burn-McKeown syndrome
Burn-McKeown syndrome (BMKS, ORPHA:1200, OMIM 608572), also called oculo-oto-facial dysplasia, is an ultra-rare autosomal recessive spliceosomopathy from biallelic TXNL4A variants, causing bilateral choanal atresia, eyelid coloboma, hearing loss, and cardiac defects with normal intelligence.
Burning feet syndrome
Burning feet syndrome, or Grierson-Gopalan syndrome, is burning, painful feet that worsen at night, usually from peripheral neuropathy, especially diabetes; also linked to vitamin deficiencies, including pantothenic acid and excess B6.
Burning mouth syndrome
Burning mouth syndrome (BMS), also called glossodynia or stomatodynia, is a chronic intraoral burning pain with normal mucosa and no identifiable cause, most common in postmenopausal women, linked to small fiber neuropathy, and best treated with clonazepam.
Burning of skin
Burning of skin (ICD-11 ME65.0) is a cutaneous symptom of burning sensation with no identified cause, grouped with itching, stinging, and tingling under disturbances of skin sensation of unspecified aetiology.
BURNSCARCARE trial
BURNSCARCARE (NCT07186322) is a Brazilian randomized trial at Federal University of São Paulo comparing autologous fat grafting with corticosteroid injection for upper limb burn scars in 40 adults, with POSAS at 6 months as the primary outcome.
Burosumab
Burosumab (Crysvita, KRN23) is a human IgG1 monoclonal antibody against FGF23, approved from 2018 for X-linked hypophosphatemia in children and adults and for tumor-induced osteomalacia, restoring renal phosphate reabsorption.
Burpee (exercise)
The burpee, also called the burpee test, is a full-body exercise moving from a squat into a plank and push-up, then a jump, invented by Royal H. Burpee in 1939.
Bursectomy
Bursectomy is a surgical procedure that removes an inflamed bursa, the fluid-filled sac that cushions bone against overlying soft tissue, reserved for bursitis unresponsive to rest, medication, aspiration, and injections.
Bursitis
Bursitis is painful inflammation of a bursa, one of over 150 fluid-filled sacs cushioning joints; most common in shoulder, elbow, knee, and heel, caused by overuse, trauma, gout, or infection, and usually resolving with rest within weeks.
Burst stimulation
Burst stimulation is a spinal cord stimulation waveform that delivers pulses in short high-frequency packets, relieving neuropathic pain without paresthesia; the FDA approved it in October 2016.
Burzynski Clinic
Burzynski Clinic, Houston, Texas clinic founded 1977 by Stanislaw Burzynski, known for unproven, FDA-unapproved antineoplaston cancer therapy, NCI-inconclusive evidence, and Texas Medical Board sanctions.
Buserelin
Buserelin (trade names Suprefact, Suprecur) is a synthetic nonapeptide analog of GnRH that first stimulates, then suppresses, pituitary hormone release, and treats prostate cancer, endometriosis, and breast cancer.
Bushen Huoxue Decoction
补肾活血汤 (Bushen Huoxue Decoction), a traditional Chinese medicine formula combining kidney-tonifying and blood-activating herbs for kidney-deficiency blood-stasis patterns; studied in diabetic nephropathy, chronic kidney disease, osteoporosis, and knee osteoarthritis.