25,729 articles
Carrimycin
Carrimycin (可利霉素, Bite, formerly bitespiramycin) is a Chinese 16-membered macrolide antibiotic made by synthetic biology, approved by NMPA on 24 June 2019 for respiratory infections.
CART-SIE study
CART-SIE (NCT06339255) is an Italian multicenter prospective observational study of real-world CAR-T therapy for relapsed/refractory DLBCL, PMBCL, MCL, and FL, coordinated from Milan, reporting feasibility, survival, toxicity, non-relapse mortality, and secondary malignancies.
Cartalax
Cartalax (Kartalax, AED, T-31) is a synthetic Khavinson bioregulator tripeptide, Ala-Glu-Asp, marketed for cartilage research; its sequence is disputed, evidence is preclinical and institute-only, and no human trial or regulatory approval exists.
Cartilage
Cartilage: non-vascular connective tissue of chondrocytes in a collagen and chondroitin sulfate matrix; hyaline, fibrocartilage, and elastic types; cushions joints, heals poorly, repaired by microfracture, ACI, MACI.
Cartilage tympanoplasty
Cartilage tympanoplasty is a surgical technique that repairs a perforated eardrum with a rigid cartilage graft, usually from the tragus, achieving better anatomical outcomes than fascia grafts.
Cartilage-hair hypoplasia
Cartilage-hair hypoplasia (CHH), or McKusick type metaphyseal chondrodysplasia, is a rare autosomal recessive disorder caused by RMRP gene variants, causing short-limb short stature, sparse hair, immunodeficiency, anemia, and cancer risk.
Carvajal syndrome
Carvajal syndrome is a rare genetic disorder with woolly hair, thickened skin on the palms and soles, and dilated cardiomyopathy that can be fatal in childhood.
Carvedilol
Carvedilol (Coreg) is a nonselective beta blocker with alpha1-blocker vasodilator and antioxidant activity; first adrenoreceptor blocker approved for heart failure (US 1997), one of three mortality-reducing beta blockers in HFrEF.
Cas12a assay
A Cas12a assay is a CRISPR-based nucleic acid detection method in which target-bound Cas12a cuts nearby single-stranded DNA reporters, giving a fluorescent signal that detects viruses, bacteria, and cancer DNA.
CASABLANCA study
CASABLANCA (Catheter Sampled Blood Archive in Cardiovascular Diseases), NCT00842868: prospective single-center biomarker study of 1251 angiography patients at Massachusetts General Hospital, 2008-2011, predicting cardiovascular, neurologic, and renal complications.
Cascade testing
Cascade testing, also called cascade screening, is a genetic epidemiology strategy in which relatives of a person with a pathogenic variant are informed and offered targeted testing.
Case fatality rate
The case fatality rate (CFR), or case fatality risk, is the proportion of people diagnosed with a disease who die from it, used to measure disease severity.
Case Management
Case management, or care coordination, is a health and social care intervention in which a case manager assesses needs, plans and arranges services, monitors delivery, and advocates for clients with complex conditions; practiced by nurses and social workers under CMSA, ACMA, and NASW standards.
Case Managers
Case managers coordinate health and social care for high-risk patients through assessment, care planning, and advocacy. Evidence shows improved satisfaction and guideline adherence but no clear reduction in hospital use, costs, or mortality.
Case-cohort study
A case-cohort study is an epidemiological design in which a random subcohort sampled at baseline is compared with all cohort cases, allowing efficient hazard-ratio estimation in large cohorts.
Case-crossover design
The case-crossover design is an epidemiological study design in which each person experiencing an acute event serves as their own control, comparing recent transient exposure with their usual exposure.
Case-crossover study
A case-crossover study is an epidemiological design where each subject serves as their own control, comparing exposures just before an acute event with exposures at other times.
Case–control study
Case–control study: an observational epidemiologic design comparing people with a disease (cases) against controls, examining past exposures; measured by the odds ratio, efficient for rare outcomes, central to the 1950 smoking–lung cancer studies.
Casey Means
Casey Means (born 1987) is a Stanford-trained physician, Levels co-founder, and co-author of the 2024 bestseller Good Energy; Trump nominated her as Surgeon General in 2025 but withdrew the stalled nomination in April 2026.
CASH trial
CASH (Children Active to Stay Healthy), NCT01821313, was a completed Nationwide Children's Hospital randomized trial comparing six weeks of high-intensity interval exercise versus moderate cycling in 34 sedentary adolescents with obesity, measuring inflammation and endothelial function.
Casimersen
Casimersen (Amondys 45) is a phosphorodiamidate morpholino antisense oligomer that skips exon 45 of the DMD pre-mRNA; FDA accelerated approval February 25, 2021, for exon 45-amenable Duchenne muscular dystrophy, dosed 30 mg/kg weekly intravenously.
Casimir A. Kulikowski
Casimir A. Kulikowski is a Board of Governors Professor of Computer Science at Rutgers University and a pioneer of artificial intelligence in medicine and biomedical informatics.
Casopitant
Casopitant, development code GW679769 and proposed brand name Zunrisa, is an NK1 receptor antagonist developed by GlaxoSmithKline against nausea and vomiting; its European marketing application was withdrawn in 2009 over safety data needs.
Cass Review
Cass Review: independent NHS England review of children's gender identity services led by Hilary Cass; interim 2022, final April 2024; found weak evidence, ended routine puberty blockers, reshaped UK policy.
Cassava poisoning
Cassava poisoning: cyanide intoxication from the cyanogenic glucosides linamarin and lotaustralin in insufficiently processed bitter cassava, causing acute poisoning and the paralytic disease konzo in sub-Saharan Africa.
Cassey Ho
Cassey Ho is an American fitness entrepreneur, creator of the Blogilates YouTube channel (2009) and POP Pilates, and founder of the Popflex and Target-exclusive Blogilates activewear brands; known for the 2015 Perfect Body video and bootstrapped eight-figure businesses.
Castleman disease
Castleman disease (angiofollicular lymph node hyperplasia) is a rare lymphoproliferative disorder with unicentric and multicentric forms, driven partly by IL-6 and HHV-8, treated by surgery or siltuximab.
Caswell A. Evans Jr.
Caswell A. Evans Jr. is an American dentist and dental public health specialist, best known as executive editor of the first Surgeon General's report on oral health in 2000.
Cat meat
Cat meat (thịt mèo, "little tiger") is domestic cat flesh eaten in a few countries, mainly Vietnam, where over 1 million cats are trafficked yearly; banned in Taiwan, China, and the US.
Cat-eye syndrome
Cat-eye syndrome (Schmid-Fraccaro syndrome), a rare chromosomal disorder from partial tetrasomy or trisomy of 22q11, marked by iris coloboma, anal atresia, preauricular tags, and heart and kidney defects.