edgepedia

Human health and medicine

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Chronic paronychia

Chronic paronychia is a recurrent or persistent inflammation of the nail folds lasting six weeks or longer, seen in people with chronically wet hands such as dishwashers and bartenders.

Chronic pelvic inflammatory disease

Chronic pelvic inflammatory disease (chronic PID, ICD-11 GA05.1) is persistent inflammation and scarring of the female upper genital tract after ascending infection, causing pelvic adhesions, chronic pelvic pain, infertility, and ectopic pregnancy risk.

Chronic peripheral neuropathic pain

Chronic peripheral neuropathic pain, ICD-11 code MG30.51, is chronic pain from a lesion or disease of the peripheral somatosensory nervous system, persisting or recurring at least 3 months, diagnosed by plausible neuroanatomical distribution and graded possible, probable, or definite.

Chronic pharyngitis

Chronic pharyngitis, also called persistent sore throat or chronic sore throat (ICD-11 CA09.2), is persistent or recurrent pharyngeal inflammation lasting over 10 days, usually noninfectious, with simple, hypertrophic, and atrophic forms.

Chronic pneumonitis of infancy

Chronic pneumonitis of infancy (CPI, ORPHA91359) is a rare infantile interstitial lung disease with alveolar septal thickening, type 2 pneumocyte hyperplasia, and primitive mesenchymal cells, usually linked to SFTPC surfactant protein C mutations.

Chronic post cancer treatment pain

Chronic post cancer treatment pain (ICD-11 MG30.11) is chronic pain caused by cancer treatment such as chemotherapy, radiotherapy, or surgery, including CIPN, lasting over 3 months and distinct from tumor recurrence pain.

Chronic post traumatic pain

Chronic post traumatic pain (ICD-11 MG30.20) is pain developing or worsening after tissue injury, including burns, persisting at least 3 months beyond healing; incidence 46-85% after multitrauma, often neuropathic, and distinct from chronic postsurgical pain.

Chronic primary musculoskeletal pain

Chronic primary musculoskeletal pain is an ICD-11 diagnosis (MG30.02, effective 2022) for chronic pain in muscles, bones, joints, or tendons, with emotional distress or disability and no other cause.

Chronic proliferative peritonitis

Chronic proliferative peritonitis (慢性増殖性腹膜炎), ICD-11 DC50.12, also called sclerosing encapsulating peritonitis: extensive peritoneal fibrosis from asbestos or CAPD, causing intestinal obstruction via massive adhesions; maps to ICD-10 K65.8.

Chronic prostatitis/chronic pelvic pain syndrome

Chronic prostatitis/chronic pelvic pain syndrome, also called chronic nonbacterial prostatitis, is a chronic pelvic pain condition of unknown cause making up about 90% of prostatitis cases.

Chronic pulmonary aspergillosis

Chronic pulmonary aspergillosis (CPA), ICD-11 1F20.12, is a slow, relapsing Aspergillus lung infection in people with prior TB, COPD, or cavities; diagnosed by IgG and CT, treated with long-term oral triazoles such as itraconazole.

Chronic pulmonary coccidioidomycosis

Chronic pulmonary coccidioidomycosis, also called chronic fibrocavitary Valley fever, is persistent Coccidioides lung infection developing in 3-5% of cases, treated with fluconazole or itraconazole and sometimes surgery.

Chronic pulmonary thromboembolism

Chronic pulmonary thromboembolism (ICD-11 BB00.1), also called CTEPH when pulmonary hypertension develops, is organized thromboembolic obstruction of pulmonary arteries after acute embolism; treated by pulmonary endarterectomy, balloon pulmonary angioplasty, and riociguat.

Chronic recurrent multifocal osteomyelitis

Chronic recurrent multifocal osteomyelitis (CRMO), also called chronic nonbacterial osteomyelitis (CNO), is a rare autoinflammatory bone disease of children with recurrent sterile osteomyelitis, treated first with NSAIDs.

Chronic respiratory acidosis

Chronic respiratory acidosis, also called chronic hypercapnic acidosis or ventilatory failure, is gradual CO2 retention from hypoventilation, mainly in COPD, obesity hypoventilation syndrome, and neuromuscular disease, with renal bicarbonate compensation of about 3.5 mEq/L per 10 mmHg PaCO2 rise.

Chronic respiratory disease

Chronic respiratory disease is a long-term disease of the airways or lungs that limits breathing, chiefly COPD, asthma, interstitial lung disease, cystic fibrosis, and pulmonary hypertension.

Chronic respiratory failure

Chronic respiratory failure is a long-lasting inability of the respiratory system to maintain normal blood gases, commonly caused by COPD, lung, chest wall, and neuromuscular diseases.

Chronic rheumatic pericarditis

Chronic rheumatic pericarditis (ICD-10-CM I09.2, ICD-11 BB21, formerly ICD-9 393) is persistent pericardial inflammation or thickening from past rheumatic fever, distinct from acute rheumatic pericarditis (I01.0), potentially causing constrictive physiology treated by pericardiectomy.

Chronic rhinitis

Chronic rhinitis, also called persistent rhinitis, is long-term nasal mucosa inflammation with obstruction, rhinorrhea, sneezing, or itch lasting 12 weeks yearly; subtypes include allergic, nonallergic, infectious, and mixed rhinitis.

Chronic rhinosinusitis

Chronic rhinosinusitis is long-term inflammation of the nasal and sinus lining lasting at least 12 weeks, with nasal blockage, discharge, facial pain, or smell loss.

Chronic secondary headache or orofacial pain

Chronic secondary headache or orofacial pain is an ICD-11 diagnostic category (code MG30.6) covering headache or facial pain from an identified underlying cause on 15 or more days a month.

Chronic secondary musculoskeletal pain

Chronic secondary musculoskeletal pain (ICD-11 MG30.3) is chronic pain in bones, joints, muscles, or tendons caused by an underlying disease: persistent inflammation, structural changes, or neurological disease, unlike chronic primary pain.

Chronic secondary visceral pain

Chronic secondary visceral pain (ICD-11 MG30.4) is chronic pain from internal organs of the head/neck, thoracic, abdominal, or pelvic cavities, secondary to inflammation, vascular, or mechanical causes, distinct from chronic primary visceral pain.

Chronic spontaneous urticaria

Chronic spontaneous urticaria (CSU), also called chronic idiopathic urticaria, is spontaneous itchy wheals or angioedema lasting over 6 weeks without an external trigger; mast cell–driven, about 1% prevalence, treated with antihistamines, omalizumab, or cyclosporine.

Chronic suppurative otitis media

Chronic suppurative otitis media (CSOM), also called chronic otitis media, is a chronic middle ear infection with discharge through a perforated eardrum and hearing loss; about 297 million people are affected, mostly in low- and middle-income countries, and treatment centers on ear cleaning and topical quinolone drops.

Chronic tension-type headache

Chronic tension-type headache (CTTH, ICHD-3 2.3, ICD-11 8A81.2) is a primary headache with headache on 15+ days/month, bilateral pressing pain; amitriptyline is first-line prophylaxis, with acupuncture and physiotherapy as options.

Chronic thromboembolic pulmonary hypertension

Chronic thromboembolic pulmonary hypertension (CTEPH), group 4 pulmonary hypertension from organized thrombotic pulmonary artery obstruction. Treated by pulmonary endarterectomy, balloon pulmonary angioplasty, and riociguat; 3-year survival 94% with surgery.

Chronic total occlusion of coronary artery

Chronic total occlusion (CTO) of a coronary artery: complete TIMI 0 blockage lasting over 3 months, found in 15–25% of angiograms; treated by specialized antegrade and retrograde PCI techniques, mainly for symptom relief.

Chronic traumatic encephalopathy

Chronic traumatic encephalopathy (CTE) is a progressive tauopathy linked to repetitive head impacts in contact sports, military service, and domestic violence; diagnosable only postmortem, with contested prevalence and dose–response.

Chronic tubotympanic suppurative otitis media

Chronic tubotympanic suppurative otitis media (CSOM, tubotympanic type, ICD-11 AA91.0) is a chronic middle ear infection with a persistent pars tensa perforation, recurrent ear discharge, and 20-60 dB conductive hearing loss, treated with topical quinolones and surgery.