Human health and medicine

CT texture analysis

CT texture analysis (CTTA) is a radiomics method that extracts statistical texture features from CT images to quantify tissue and lesion heterogeneity, used in tumor grading, prognosis, and therapy response assessment.

CT urography

CT urography (CTU) is a computed tomography scan of the urinary tract with intravenous contrast, used for hematuria workup and staging of urinary tract cancers.

CT-CROP trial

CT-CROP (NCT02395939) trial: multicentre Australia-New Zealand randomized trial comparing R-EBUS guided cryobiopsy (Cryo-Radial) with CT-guided transthoracic biopsy for peripheral pulmonary lesions; similar diagnostic yield (85% vs 93.8%) with far fewer pneumothoraces (4.2% vs 44%).

CT-guided biopsy

CT-guided biopsy is a percutaneous diagnostic procedure in which computed tomography guides a needle into a suspected lesion to obtain tissue samples, first reported in 1976.

CT032 (CD19 CAR-T)

CT032 (CT-032, CSG-CD19) is CARsgen Therapeutics' autologous humanized-scFv CD19-targeted CAR-T candidate for relapsed/refractory B-cell non-Hodgkin lymphoma, in a Chinese Phase I/II trial (NCT03994913) and licensed for South Korea to HK inno.N.

ctDNA assay

A ctDNA assay is a blood-based diagnostic test that detects circulating tumor DNA released by tumors, used to select therapy, detect molecular residual disease, and monitor relapse.

ctDNA monitoring

CtDNA monitoring is a liquid-biopsy method that repeatedly measures tumor-derived DNA fragments in blood plasma to track tumor burden over time, detecting colorectal cancer recurrence a mean 8.7 months before imaging.

CTO-PCI study

CTO-PCI study: percutaneous coronary intervention for chronic total coronary occlusions (blockages of at least 3 months), and the J-CTO, PROGRESS-CTO, CL, and CASTLE scoring systems predicting procedural success and wire-crossing difficulty.

CTV-1

CTV-1 (CVCL_1150, DSMZ ACC-40) is a human leukemia cell line established in 1984 from relapsed acute monoblastic leukemia but now classified as T-ALL; MSI-high, male STR profile, Lck-driven proliferation, used in DepMap and COSMIC.

Cubital fossa

Cubital fossa (antecubital fossa): triangular depression on the front of the elbow bounded by brachioradialis, pronator teres, and the inter-epicondylar line; contains radial nerve, biceps tendon, brachial artery, and median nerve; main venipuncture site.

Cubital tunnel syndrome

Cubital tunnel syndrome (CuTS), ulnar nerve entrapment at the elbow, is the second most common upper-limb compression neuropathy, causing little and ring finger numbness worsened by elbow flexion; treated first conservatively, then by in situ decompression or transposition.

Cubitus valgus

Cubitus valgus, an increased elbow carrying angle beyond age- and sex-matched norms, usually from lateral condylar fracture malunion or nonunion; causes tardy ulnar nerve palsy and is corrected by supracondylar osteotomy.

Cubitus varus

Cubitus varus, or gunstock deformity, is a triplanar varus, extension, and internal rotation deformity of the elbow caused by malunion of pediatric supracondylar humeral fractures, treated mainly by corrective distal humeral osteotomy.

Cukkumtippalyadi Gutika

Cukkumtippalyadi Gutika (Chukkumthippalyadi Gulika), a Kerala Ayurvedic herbo-mineral pill of dry ginger, long pepper, and purified minerals, AFI Part 1 12:12, dose 250 mg, used for sannipataja jwara (fever), cough, and digestive complaints.

Culdoscopes

Culdoscopes are endoscopic instruments passed through the vaginal wall into the rectovaginal pouch to view the pelvic viscera. Devised by Albert Decker, they dominated US gynecological endoscopy circa 1950-1970 before laparoscopy displaced culdoscopy.

Culdoscopy

Culdoscopy, also called transvaginal endoscopy, is a gynecologic procedure in which a culdoscope is inserted through the posterior vaginal fornix into the pouch of Douglas. Developed by Albert Decker in the 1940s, it dominated US gynecologic endoscopy circa 1950-1970 before laparoscopy supplanted it.

Culevibart

Culevibart (库莱韦拜单抗, RB0026, brand Inmular/英沐乐) is a long-acting human IgG1 monoclonal antibody against RSV F protein site II, approved by China's NMPA on September 3, 2026 for RSV prophylaxis in infants ≥35 weeks' gestation.

Culmerciclib capsules

Culmerciclib capsules (库莫西利胶囊, 赛坦欣) is the first approved CDK2/4/6 inhibitor, a Chia Tai Tianqing oral drug for HR+/HER2- breast cancer with fulvestrant, NMPA-approved December 2025.

CULPRIT-SHOCK trial

CULPRIT-SHOCK (Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock), NCT01927549: European randomized trial of 706 AMI patients with cardiogenic shock and multivessel disease showing culprit-lesion-only PCI beat immediate multivessel PCI at 30 days (45.9% vs 55.4% death or renal replacement), reshaping guidelines.

Culture-bound syndrome

Culture-bound syndrome, now called cultural concepts of distress in DSM-5, refers to patterns of mental distress recognized within specific cultures, such as koro, ataque de nervios, and taijin kyofusho, lacking formal diagnostic criteria.

Cupping therapy

Cupping therapy, also known as suction cupping or baguan, is a traditional medicine practice that draws skin into cups by suction, used in China and the Middle East.

Curandero

A curandero (feminine curandera) is a traditional folk healer in Mexican and Mexican American communities, part of a healing system called curanderismo that clients often use alongside conventional medicine.

CURATP trial

CURATP (NCT05784610) is a pilot pre-post quasi-experimental trial at Poitiers University Hospital comparing automated ATP-mode TofScan monitoring with manual TOF/PTC monitoring for maintaining deep neuromuscular blockade during laparoscopic abdominal surgery with rocuronium, enrolling 60 adults.

CURB-65

CURB-65: five-point pneumonia severity score (confusion, urea >7 mmol/L, respiratory rate ≥30, low blood pressure, age ≥65) predicting 30-day mortality in community-acquired pneumonia and guiding hospital versus home care; CRB-65 is its urea-free primary care variant.

CurChexia trial

CurChexia (NCT04208334) was a Thai phase IIa double-blind placebo-controlled trial of oral curcumin 4,000 mg daily for 8 weeks in 20 head and neck cancer patients with cancer anorexia-cachexia syndrome, showing significant muscle mass gain versus placebo.

Cure Rare Disease

Cure Rare Disease (CRD) is a Connecticut 501(c)(3) nonprofit biotech founded by Rich Horgan for his brother Terry's ultra-rare DMD. It ran the first-in-human CRISPRa N-of-1 trial CRD-TMH-001 (patient died from AAV immune reaction, 2022) and develops ASO and gene therapies for SCA3, LGMD2i/R9, and ANO5-related disease.