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Human health and medicine

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Cutaneous sarcoma

Cutaneous sarcoma is a rare malignant skin tumor arising from mesenchymal connective-tissue cells such as fibroblasts, smooth muscle, and vascular endothelium, classified under ICD-11 code 2C35.

Cutaneous tuberculosis

Cutaneous tuberculosis (CTB, tuberculosis cutis) is rare skin infection by Mycobacterium tuberculosis, about 1–2% of TB cases. Forms include lupus vulgaris, scrofuloderma, TB verrucosa cutis, and tuberculids; diagnosed by biopsy, culture, and PCR.

Cutberto Garza

Cutberto Garza is an American physician and nutrition scientist, longtime leader of Cornell's nutrition division, who chaired the WHO Child Growth Standards effort and the 1999 U.S. Dietary Guidelines Advisory Committee.

Cuticle

Cuticle: the eponychium, the skin band sealing the nail plate to the proximal nail fold, and the outermost protective cell layer of a hair shaft; both barriers, damage causes paronychia or split ends.

Cutis

Cutis is a monthly peer-reviewed US clinical dermatology journal founded in 1965, ISSN 0011-4162, indexed in MEDLINE since 1976, published by Frontline Medical Communications, with SJR 0.276 (Q3) and no author APC.

Cutis gyrata-acanthosis nigricans-craniosynostosis syndrome

Cutis gyrata-acanthosis nigricans-craniosynostosis syndrome, or Beare-Stevenson syndrome (BSS), a rare severe FGFR2-related craniosynostosis with cutis gyrata, acanthosis nigricans, cloverleaf skull, and high infant mortality.

Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies

Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies, also called Urban-Rifkin-Davis syndrome or ARCL1C (OMIM 613177), is an autosomal recessive LTBP4-related connective tissue disorder with neonatal onset, generalized lax skin, early-onset emphysema, and bladder, intestinal, and kidney anomalies.

Cutis marmorata telangiectatica congenita

Cutis marmorata telangiectatica congenita (CMTC, van Lohuizen syndrome) is a rare congenital capillary malformation causing persistent marbled skin, distinguished from physiologic cutis marmorata by failure to resolve with warming; GNA11 mosaicism, glaucoma risk.

Cutis verticis gyrata

Cutis verticis gyrata (CVG) is a rare scalp condition in which thickened skin forms folds resembling the brain's gyri, occurring as a primary form or secondary to other disease.

CV_RCT_M_F trial

CV_RCT_M_F (NCT02747875) was a terminated randomized double-blinded trial at Children's National Health System testing 0.3 mg/kg methadone versus 20 mcg/kg fentanyl before incision in children aged 2 to 7 undergoing cardiac bypass surgery.

CWC trial

CWC trial (NCT03429166), Connecting Women to Care, a VA-sponsored randomized trial led by Marylene Cloitre comparing home-based video-delivered STAIR versus present-centered therapy in 161 rural women veterans with military sexual trauma; STAIR produced larger PTSD reductions (d = 1.12 vs 0.78).

Cyanide poisoning

Cyanide poisoning: rapid, potentially fatal toxicity from HCN, cyanogen chloride, or cyanide salts that blocks cellular oxygen use via cytochrome c oxidase inhibition; treated with oxygen and antidotes, chiefly hydroxocobalamin and sodium thiosulfate.

Cyanoacrylate injection

Cyanoacrylate injection is an endoscopic treatment in which medical-grade glue is injected into gastric varices to stop bleeding in portal hypertension, achieving hemostasis in about 90% of patients.

Cyanocobalamin

Cyanocobalamin, also called vitamin B12, is the most stable and most common supplemental form of cobalamin, a synthetic cyano-cobalt complex crystallized in 1948 and activated in the body by MMACHC decyanation.

Cyanosis

Cyanosis: bluish skin and mucous membrane discoloration from excess deoxyhemoglobin (over 5 g/dL) or abnormal hemoglobins. Types are central, peripheral, and differential; causes span lung, heart, and hemoglobin disorders.

Cyanotic attacks of newborn

Cyanotic attacks of newborn are sudden episodes of cyanosis lasting moments to half an hour in previously normal-colored infants, classified as ICD-11 code KB2C and ICD-10-CM P28.2.

Cyanotic congenital heart disease

Cyanotic congenital heart disease (CCHD) is a group of heart defects present at birth in which deoxygenated blood enters circulation, causing bluish skin and chronically low oxygen levels.

Cybathlon

Cybathlon is an international competition organized by ETH Zurich where pilots with disabilities complete everyday tasks using prostheses, exoskeletons, and brain-computer interfaces; it was first held in 2016.

Cyborg

Cyborg: a cybernetic organism, a human integrally combined with technology. Coined by Clynes and Kline in 1960 for space-flight self-regulation; today covers brain-computer implants, prosthetics, and human augmentation.

Cychlorphine

Cychlorphine, also known as N-propionitrile chlorphine, is a synthetic opioid of the orphine family with no approved medical use, estimated to be about 10 times more potent than fentanyl.

Cyclacillin

Cyclacillin (ciclacillin, Wy-4508, Cyclapen-W) is a discontinued semisynthetic penicillin, a cyclohexylamido analog of penicillanic acid, FDA-approved in 1979, with faster and higher absorption than ampicillin and lower diarrhea rates than amoxicillin.

Cyclandelate

Cyclandelate (Cyclospasmol, CAS 456-59-7) is a mandelic acid ester vasodilator, a direct-acting smooth muscle relaxant once used for claudication, Raynaud's disease, and migraine prophylaxis; discontinued in the US and Canada in 1997 for lack of efficacy.

Cycle ergometry

Cycle ergometry is an exercise testing method in which a patient pedals a stationary bicycle ergometer against controlled resistance, with power output prescribed in watts and cardiopulmonary responses recorded.

Cyclic neutropenia

Cyclic neutropenia, also called cyclic hematopoiesis, is a rare autosomal dominant ELANE-related immunodeficiency with ~21-day oscillations of neutrophil counts to ANC <0.2×10⁹/L, causing recurrent fever, mouth ulcers, and infections, treated with G-CSF.

Cyclic pelvic pain

Cyclic pelvic pain (ICD-11 GA34.20), also called mittelschmerz or ovulatory pain, is recurrent pelvic pain tied to the menstrual cycle; dysmenorrhea is its commonest cause, with endometriosis the key secondary differential.

Cyclic vomiting syndrome

Cyclic vomiting syndrome (CVS), a functional gut-brain disorder with recurrent stereotypical vomiting episodes separated by symptom-free intervals; key differential is cannabinoid hyperemesis syndrome; migraine-linked, treated with tricyclics and antiemetics.

Cyclizine

Cyclizine (Marezine, Valoid) is a piperazine H1 antihistamine antiemetic developed by Burroughs Wellcome in 1947, used for motion sickness, vertigo, and PONV, and carried on Apollo missions for space sickness.

Cyclobarbital

Cyclobarbital (cyclobarbitone, Phanodorm, Cyclodorm) is a rapid, short-acting barbiturate hypnotic, 5-(1-cyclohexen-1-yl)-5-ethylbarbituric acid, ATC N05CA10, WHO DDD 0.2 g oral, UN Schedule III.

Cyclobenzaprine

Cyclobenzaprine (Flexeril) is a tricyclic, centrally acting skeletal muscle relaxant, structurally related to amitriptyline, approved in 1977 for short-term relief of acute musculoskeletal muscle spasm, ineffective for spasticity.

Cyclodextrin nanoparticles

Cyclodextrin nanoparticles are drug-delivery particles in which cyclodextrins, cyclic sugars with hydrophobic cavities, improve the solubility, stability, and targeting of drugs, most notably in cancer therapy.