edgepedia

Human health and medicine

25,729 articles

EARTH study

The Environment and Reproductive Health (EARTH) Study is a preconception cohort study at Massachusetts General Hospital in Boston investigating how environmental, nutritional, and lifestyle factors affect fertility and pregnancy outcomes.

Earwax

Earwax, or cerumen, is the waxy secretion of ear canal glands that protects and cleans the ear. Wet and dry types follow the ABCC11 gene; impaction affects up to 30% of people and is treated with softeners, irrigation, or manual removal.

East Asian Traditional Medicine

East Asian traditional medicine covers TCM, TKM, and Japanese Kampo/Oriental medicine, sharing a Chinese origin about 3,000 years ago; uses acupuncture, moxibustion, cupping, and herbs, with differing national regulation, insurance, and evidence bases.

EAST syndrome

EAST syndrome, also called SeSAME syndrome, is a rare autosomal recessive KCNJ10 (Kir4.1) channelopathy causing infantile epilepsy, ataxia, sensorineural deafness, and renal salt-wasting tubulopathy with hypokalemia and hypomagnesemia.

EAST trial

The EAST trial, formally EAST-AFNET 4, was an international randomized trial of 2,789 patients showing early rhythm control for atrial fibrillation cut cardiovascular death, stroke, and hospitalization by 21%.

Eastern Maine Medical Center

Northern Light Eastern Maine Medical Center (EMMC), Bangor, Maine; founded 1892 as Bangor General Hospital; flagship of Northern Light Health; Level 2 Trauma Center, Stroke Center of Excellence, 411 beds.

Eating

Eating is the ingestion of food through the mouth for nourishment, covering mastication, swallowing, brain-regulated satiety, the evolution of human diets, and modern guidance on ultraprocessed foods and healthy eating patterns.

Eating disorder

Eating disorder: mental disorders involving disturbed eating and body-weight concerns, mainly anorexia nervosa, bulimia nervosa, binge-eating disorder, and ARFID; 18 million cases in 2023, treated chiefly with CBT-ED and family-based therapy.

Eating Disorder Examination

The Eating Disorder Examination (EDE) is a semi-structured interview developed by Zafra Cooper and Christopher Fairburn, first published in 1987 and considered the gold standard eating disorder assessment.

Eating Disorder Examination questionnaire

The Eating Disorder Examination questionnaire (EDE-Q) is a 28-item self-report measure of eating disorder psychopathology, adapted from the EDE interview and introduced by Fairburn and Beglin in 1994.

Eating of non-nutritive substances

Eating of non-nutritive substances, ICD-11 code MB29.2, is the behavior called pica in DSM-5-TR: persistent eating of non-food items such as clay, ice, starch, or hair for over one month, excluding children under two and culturally sanctioned practice.

Eating reflex epilepsy

Eating reflex epilepsy (eating epilepsy, ORPHA:166418) is a rare reflex epilepsy in which seizures are triggered by eating, chewing, or food-related stimuli. Onset typically in the second decade, male predominance, focal impaired-awareness seizures, temporolimbic or perisylvian onset.

EB2 [Human Burkitt lymphoma]

EB2 (EB-2, Epstein-Barr-2, CVCL_1186, ATCC HTB-61) is an EBV-transformed human B-lymphoblast cell line from a 7-year-old Ugandan girl's metastatic ovarian Burkitt lymphoma, established by Epstein, Barr, and Achong in 1965.

Ebastine

Ebastine is a non-sedating second-generation oral H1 antihistamine taken once daily, with or without food, for allergic rhinitis and chronic idiopathic urticaria, acting through its active metabolite carebastine.

Ebdarokimab

Ebdarokimab (AK101, Aidaro, 依若奇单抗) is a human IgG1κ monoclonal antibody by Akeso binding the IL-12/IL-23 p40 subunit; approved in China April 2025 for moderate-to-severe plaque psoriasis, 135 mg SC, PASI 75 79.4% at week 16.

Eben Alexander (author)

Eben Alexander III (born 1953) is an American neurosurgeon and author of Proof of Heaven (2012), a #1 New York Times bestseller about his 2008 near-death experience during an E. coli meningitis coma; his consciousness claims are contested by neuroscientists.

Eben Byers

Eben MacBurney Byers, Pittsburgh industrialist and 1906 U.S. amateur golf champion, died of radium poisoning in 1932 after drinking about 1,400 bottles of the radioactive patent medicine Radithor, prompting its removal and stronger FDA regulation.

Eben L. Rosenthal

Eben Lloyd Rosenthal is an American head and neck surgical oncologist who chairs Otolaryngology at Vanderbilt University Medical Center and studies fluorescent dyes that make cancer visible during surgery.

Ebola in Uganda

Ebola in Uganda refers to the recurring Ebola virus disease outbreaks Uganda has experienced since the first confirmed episode in Gulu District in 2000, caused successively by Sudan, Bundibugyo, and Zaire ebolaviruses.

Ebola vaccine

Ebola vaccine: vaccines against orthoebolaviruses, chiefly Ervebo (rVSVΔG-ZEBOV-GP, Merck), the only licensed, WHO-prequalified Ebola vaccine (EMA/FDA 2019), used in ring vaccination; no licensed vaccine for Bundibugyo or Sudan virus disease.

Ebola virus cases in the United States

Ebola virus cases in the United States: 11 patients treated in 2014–2016, including Thomas Eric Duncan and the first domestically acquired cases (nurses Nina Pham and Amber Vinson) in Dallas, plus aid worker Craig Spencer in New York.

EBOVAC3DRC trial

EBOVAC3DRC (EBL2007, NCT04186000) is an open-label Phase 2 trial of the two-dose Ad26.ZEBOV plus MVA-BN-Filo Ebola vaccine regimen, with optional Ad26 boosters, in health care providers in Boende, DRC, under the EBOVAC3/IMI2 project.

Ebronucimab (AK102)

Ebronucimab (伊努西单抗, AK102, brand 伊喜宁) is a fully human IgG1 anti-PCSK9 monoclonal antibody by Akeso/AD Pharmaceuticals, approved in China on 26 September 2024 for primary hypercholesterolemia and mixed dyslipidemia, dosed 150 mg Q2W or 450 mg Q4W.

Ebrotidine

Ebrotidine (FI-3542, CAS 100981-43-9) is an H2-receptor antagonist antiulcer drug with added cytoprotective and anti-Helicobacter pylori activity, tested in phase II and III trials against ranitidine for peptic ulcer.

Ebstein's anomaly

Ebstein malformation of the tricuspid valve (Ebstein anomaly), a rare congenital heart defect with apically displaced tricuspid leaflets and atrialized right ventricle; described by Wilhelm Ebstein in 1866, treated by cone repair.

EC regimen (chemotherapy)

The EC regimen is a two-drug chemotherapy combination of epirubicin and cyclophosphamide, used mainly as neoadjuvant or adjuvant treatment for breast cancer over 3 to 6 cycles.

EC50

EC50 (half maximal effective concentration) is the agonist concentration producing a response halfway between baseline and maximum; the standard potency measure in pharmacology, derived from the 1910 Hill equation, distinct from IC50 and Kd.

ECA stack

ECA stack: ephedrine, caffeine, and aspirin combination promoted for weight loss and athletic performance. Modest short-term fat loss (~2 lb/month with ephedrine plus caffeine), 2-3x side-effect risk; ephedra supplements banned by FDA in 2004.

Ecabet

Ecabet is a diterpenoid anti-ulcer drug, marketed in Japan as ecabet sodium, taken orally for gastric ulcers and gastritis and studied for eliminating H. pylori.

Ecallantide

Ecallantide (Kalbitor, DX-88) is a recombinant 60-amino-acid plasma kallikrein inhibitor (Ki 25 pM) injected subcutaneously, 30 mg, for acute hereditary angioedema attacks; US-only approval (2009), boxed warning for anaphylaxis (4%).