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Ectopic pregnancy
An ectopic pregnancy, also called a tubal or extrauterine pregnancy, is one that implants outside the uterus, usually in a fallopian tube, and can cause life-threatening rupture.
Ectopic testis
Ectopic testis (ICD-11 LB52.0), a form of cryptorchidism in which the testis lies outside its normal descent path, most often in the superficial inguinal pouch; requires orchidopexy, usually before 12 months.
Ectopic thymus
Ectopic thymus, also called ectopic cervical or intrathyroidal thymus, is thymic tissue stranded along the embryological descent path from the third pharyngeal pouch; a benign pediatric neck or thyroid finding that can mimic cancer.
Ectrodactyly
Ectrodactyly, or split hand/foot malformation (SHFM), cleft hand, is a congenital central-ray limb deficiency causing missing central fingers or toes; typical (V-shaped, genetic, bilateral) versus atypical (U-shaped, sporadic) forms, TP63/DLX/WNT10B genes, EEC syndrome association.
Ectropion of eyelid
Ectropion of the eyelid: outward turning of the eyelid margin, usually the lower lid, exposing the inner surface. Main types involutional, cicatricial, mechanical, paralytic; treated with lubricants and lateral tarsal strip surgery.
ECV trial
ECV trial (NCT04346823), Sevoflurane and Success of External Cephalic Version: a phase 4 randomized trial by King Saud University testing 1% inhaled sevoflurane versus no intervention to raise ECV success in 40 women at 36-40 weeks.
Eczema Area and Severity Index
The Eczema Area and Severity Index (EASI) is a clinical scoring tool for atopic dermatitis, grading lesion extent and severity across body regions on a 0 to 72 scale.
Edaravone (エダラボン)
Edaravone (エダラボン; Radicut/Radicava) is a free-radical scavenging drug approved in Japan (2001) for acute ischemic stroke and in the US (2017 IV, 2022 oral) to slow decline in ALS, one of three FDA-approved ALS drugs.
Edaravone and dexborneol concentrated solution for injection
Edaravone dexborneol concentrated solution for injection (依达拉奉右莰醇注射用浓溶液, Xianbixin) is a Simcere 4:1 edaravone/(+)-dexborneol neuroprotectant, 37.5 mg twice daily for 10-14 days, approved in China for acute ischemic stroke; TASTE and TASTE-2 trials support functional benefit.
Edasalonexent
Edasalonexent (CAT-1004), an oral NF-κB inhibitor conjugating salicylic acid and DHA, was Catabasis Pharmaceuticals' experimental therapy for Duchenne muscular dystrophy; development ended in 2020 after the phase 3 PolarisDMD trial missed its endpoints.
Edema
Edema (oedema, dropsy) is soft-tissue swelling from excess interstitial fluid, caused by raised capillary pressure, low plasma oncotic pressure, capillary leak, or lymphatic obstruction; common causes are heart, liver, and kidney disease, DVT, and medications.
Edetate calcium disodium anhydrous
Edetate calcium disodium anhydrous (calcium disodium EDTA, CaNa2EDTA, CAS 62-33-9) is a chelating drug approved in 1953 for lead poisoning, distinct from edetate disodium, and also a food and cosmetic sequestrant.
Edgar B. Jackson Jr.
Edgar B. Jackson Jr. was an American internist who became the first African American chief of staff at a major academic medical center, at Cleveland's University Hospitals in 1997.
EDICT syndrome
EDICT syndrome, an acronym for its main features, is a rare autosomal dominant eye disorder caused by a microRNA mutation, producing congenital cataracts, corneal thinning, and iris hypoplasia.
Edinburgh Postnatal Depression Scale
The Edinburgh Postnatal Depression Scale (EPDS) is a 10-item self-report questionnaire screening for depression during pregnancy and postnatally, the most widely used such screening tool.
Edinger–Westphal nucleus
The Edinger–Westphal nucleus (E-W nucleus), described by Edinger in 1885 and Westphal in 1887, is a midbrain cell group whose preganglionic neurons control pupil constriction and lens accommodation.
EdiTh trial
EdiTh (Ed.iTh, NCT05098444) is a randomized controlled trial at Philipps University Marburg testing an eight-module therapist-guided internet-based CBT program against a waiting list to improve quality of life in women with endometriosis; distinct from the UK EDITH breast screening AI trial.
Edivoxetine
Edivoxetine (LY2216684) is Eli Lilly's investigational selective norepinephrine reuptake inhibitor for depression and ADHD. Three Phase 3 adjunctive MDD trials failed their primary endpoint in 2013, ending development; it was no better than placebo for ADHD.
Edmund Y.S. Chao
Edmund Y.S. Chao is an orthopedic bioengineer and Lee Riley, Jr. Professor Emeritus at Johns Hopkins, elected to the National Academy of Engineering in 1998 for limb biomechanics models.
EDO study
The EDO study (End Diagnostic Overshadowing) is a NIH-funded research program at Rush University Medical Center studying and reducing diagnostic overshadowing in patients with disabilities.
Edobacomab
Edobacomab (E5, Xomen E5, XMMEN-0E5) is a murine IgM monoclonal antibody against gram-negative bacterial endotoxin (lipid A), developed by XOMA for sepsis; its phase III trials showed no survival benefit.
Edotecarin
Edotecarin (J-107088, PHA-782615) is a synthetic indolocarbazole topoisomerase I inhibitor derived from NB-506 that reached Phase III oncology trials but was discontinued by Pfizer in 2005 for insufficient activity.
Edotreotide
Edotreotide (DOTATOC, SMT 487) is a DOTA-conjugated somatostatin analogue targeting SSTR2. Gallium-68-labeled edotreotide (SomaKit TOC) images neuroendocrine tumors by PET; yttrium-90 and lutetium-177 forms are PRRT therapies.
Edoxaban
Edoxaban is a direct oral factor Xa inhibitor anticoagulant developed by Daiichi Sankyo, marketed as Lixiana and Savaysa, used to prevent stroke in atrial fibrillation.
Edrecolomab
Edrecolomab (Panorex, 17-1A) is a murine IgG2a monoclonal antibody against EpCAM, the first monoclonal antibody approved for cancer therapy (Germany, 1995), later withdrawn after phase III trials showed no adjuvant benefit in colorectal cancer.
Eduard Bloch
Eduard Bloch (1872–1945), Austrian Jewish physician and Hitler's family doctor in Linz; treated Klara Hitler's breast cancer, was protected by Hitler as his 'Edeljude', and emigrated to New York in 1941.
EDUCAP-5FU trial
EDUCAP-5FU (NCT07061236) is a completed randomized controlled trial by Anita Karaca, Biruni University, Istanbul, testing whether a 15-20 minute structured elastomeric pump education program reduces anxiety (Beck Anxiety Inventory) and improves comfort in cancer patients receiving home 5-FU infusion; 70 enrolled, distinct from the EDUCAP pneumonia trial.
EDUQ-CPNE trial
EDUQ-CPNE (NCT02311829), a French multicenter randomized trial sponsored by Central Hospital, Nancy, testing psychologist telephone follow-up (DST) versus usual care on quality of life in video-EEG-confirmed psychogenic non-epileptic seizures.
Edward B. Perrin
Edward B. Perrin is an American biostatistician, first chair of the University of Washington's Department of Biostatistics and a former director of the National Center for Health Statistics.
Edward E. Wallach
Edward E. Wallach, born 1933, is an American reproductive endocrinologist and Johns Hopkins professor emeritus who led research on the mechanism of ovulation and assisted reproduction.