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Human health and medicine

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Eladi Curna

Eladi Churna (Elādi Cūrṇa, Eladi Choornam) is a classical Ayurvedic herbal powder led by cardamom (Ela), official in the Ayurvedic Formulary of India (AFI Part-I, 7:5) with nine equal-part ingredients, used for kasa, shvasa, and vomiting.

Eladi ghrta

Eladi ghṛta (Elādi ghṛta) is a classical Ayurvedic medicated ghee formulation from Ashtanga Hrudayam, listed in the Ayurvedic Formulary of India Part I 6:6 at 12 g, with cardamom-led herbs in cow ghee, used for abdominal pain, anemia, emaciation, eye diseases, and rejuvenation, distinct from Eladi gutika, churna, and taila.

ELADI GUTIKA

Eladi Gutika (Elaadi Gutika), an Ayurvedic polyherbal pill in the Ayurvedic Pharmacopoeia of India Part-II Vol-III, made of cardamom, cinnamon, long pepper, licorice, dates, raisins, sugar, and honey; traditionally used for cough, asthma, vomiting, vertigo, and haemoptysis.

Eladocagene exuparvovec

Eladocagene exuparvovec (Upstaza, Kebilidi) is a PTC Therapeutics AAV2 gene therapy delivering the DDC gene for AADC deficiency, approved in the EU in 2022 and by FDA in 2024.

Eladya Modaka

Eladya Modaka (Elādya modaka, एलाद्यमोदक) is a semisolid sweetened Ayurvedic avaleha from Bhaishajya Ratnavali, listed in the Ayurvedic Formulary of India (AFI000087, 12 g dose) for madatyaya, alcohol-related and digestive disorders.

Elafibranor

Elafibranor (GFT505, Iqirvo) is a dual PPAR-alpha/delta agonist approved in 2024 for primary biliary cholangitis after UDCA failure; its NASH program was discontinued after phase 3 failure.

Elagolix

Elagolix (Orilissa, Oriahnn) is the first FDA-approved oral non-peptide GnRH receptor antagonist, approved in 2018 for endometriosis pain and in 2020 with hormonal add-back for fibroid heavy menstrual bleeding.

Elaine Esposito

Elaine Esposito (1934-1978), the "sleeping beauty," fell into a coma aged six during a 1941 Chicago appendectomy and never woke, holding the Guinness longest-coma record at 37 years 111 days until her death in Florida.

Elamipretide

Elamipretide (SS-31, MTP-131, Bendavia, Forzinity) is a cardiolipin-binding mitochondria-targeting tetrapeptide, D-Arg-Dmt-Lys-Phe-NH2; FDA accelerated approval 2025 for Barth syndrome, negative MMPOWER-3 trial in mitochondrial myopathy.

Elanir kuzambu (elanirkuzambu)

Elanir Kuzambu (nālikerāñjana, Elaneer Kuzhambu), Ayurvedic anjana AFI 13:1 from Sahasrayoga verse 52; tender coconut water decoction with triphala, barberry, licorice, camphor, honey; applied to inner eyelids for corneal ulcer, pterygium, early cataract.

Elapegademase

Elapegademase (Revcovi, EZN-2279) is a PEGylated recombinant bovine adenosine deaminase given intramuscularly as enzyme replacement therapy for ADA-SCID; FDA-approved October 2018, replacing pegademase (Adagen).

ELARIS EM-I trial

ELARIS EM-I (M12-665, NCT01620528), AbbVie's phase 3 trial of elagolix 150 mg once daily and 200 mg twice daily versus placebo in 872 women with endometriosis-associated pain; pivotal for Orilissa approval.

ELARIS EM-II trial

ELARIS EM-II (NCT01931670), AbbVie phase 3 trial of elagolix (Orilissa) 150 mg once daily and 200 mg twice daily versus placebo for 6 months in 817 women with endometriosis-associated pain; both doses met dysmenorrhea and nonmenstrual pelvic pain endpoints.

Elastic therapeutic tape

Elastic therapeutic tape, or kinesiology tape (Kinesio Tape, developed by Kenzo Kase in 1979), is a stretchy cotton adhesive tape used for pain, swelling, and sports support; systematic reviews find little benefit over sham tape.

Elasticity imaging

Elasticity imaging is a family of medical imaging techniques that noninvasively map the stiffness of biological tissue using ultrasound or MRI, used mainly to stage liver fibrosis and characterize tumors.

Elastoderma

Elastoderma (ORPHA:228240) is an extremely rare acquired skin disorder with localized skin laxity and delayed recoil on elbows, knees, or neck, caused by dermal accumulation of pleomorphic elastic fibers without calcification; cause unknown, no standard therapy.

Elastofibroma dorsi

Elastofibroma dorsi (elastofibroma) is a benign, slow-growing fibroelastic soft-tissue tumor of the infrascapular chest wall, first described by Järvi and Saxén in 1961, common in elderly women, bilateral in about a third of cases, and treated conservatively unless symptomatic.

Elastoma

Elastoma, also called nevus elasticus or juvenile elastoma (Weidman), is a rare connective tissue nevus of dermal elastic fibers causing firm skin-colored to yellowish papules; isolated or with osteopoikilosis as Buschke-Ollendorff syndrome.

Elastosis perforans serpiginosa

Elastosis perforans serpiginosa (EPS) is a rare perforating skin disorder in which abnormal elastic fibers are pushed through the epidermis, forming reddish bumps in snake-like or ring patterns, often on the neck.

Elbasvir

Elbasvir (MK-8742) is an HCV NS5A inhibitor used with grazoprevir as Zepatier, a once-daily 50/100 mg tablet for chronic hepatitis C genotypes 1a, 1b, and 4; discontinued in the US market.

Elbow

The elbow (articulatio cubiti) is the compound synovial hinge joint of humerus, radius, and ulna, with three articulations, collateral ligament stabilizers, 0–140° motion, and common injuries including dislocation and epicondylitis.

Elbow arthroplasty

Elbow arthroplasty, also called total elbow arthroplasty, is an orthopedic joint replacement procedure developed for rheumatoid arthritis and now used for unfixable fractures and arthritis.

Elbow arthroscopy

Elbow arthroscopy is a minimally invasive surgical technique that diagnoses and treats conditions inside the elbow joint, including loose-body removal, capsular release, and cartilage debridement.

Elbow Prosthesis

Elbow prosthesis: implant replacing the elbow joint (MeSH D058569, 2011), mainly as total elbow arthroplasty (TEA) in linked or unlinked designs; ~84% survive 10 years; complications include infection, loosening, and ulnar neuropathy.

Eldecalcitol

Eldecalcitol (ED-71, Edirol) is a Japanese-approved 0.75 μg/day oral vitamin D3 analog for osteoporosis that lowers vertebral fracture risk and raises BMD more than alfacalcidol, with hypercalciuria as its main safety signal.

Elderly care

Elderly care (long-term care for older people) covers personal, social, and medical support for older adults losing capacity. Key facts: informal care is up to 80% of European LTC, 80+ population to triple to 426 million by 2050, and LTC workers average 5 per 100 people 65+ in OECD countries.

Elderly person

Elderly person: a human in later adult life, defined by age (UN 60+, most developed countries 65+). Covers definitions, demographics (1 billion aged 60+ in 2019), health, assessment, and policy.

ELEANOR trial

ELEANOR (NCT05438862) is a Czech-led randomized trial comparing early aortic valve surgery with watchful waiting in 217 asymptomatic severe aortic regurgitation patients at CMR-defined risk; distinct from a neratinib breast cancer study of the same name.

ELECBACK trial

ELECBACK (NCT02812459) was a Spanish randomized trial comparing back exercise plus electrical stimulation versus exercise plus Kinesio taping in chronic low back pain; both improved, with pain favoring electrical stimulation.

Eleclazine

Eleclazine (GS-6615), a Gilead sodium channel blocker selectively inhibiting cardiac late sodium current via Nav1.5 for LQT3 and hypertrophic cardiomyopathy; phase 3 trials ended with program termination in late 2016.