25,729 articles
EPF study (NCT03235310)
EPF study, NCT03235310, is the registration of the French Perinatal Cohort (ANRS CO1/CO11), a prospective observational cohort since 1986 of HIV-infected pregnant women in 90 French centers, tracking mother-to-child HIV transmission, PMTCT safety, and birth defects including the zidovudine heart-defect association.
EPF study (NCT03306251)
EPF study, NCT03306251, ANRS CO11: French national observational cohort of children born to HIV-positive mothers, run with ANRS CO1 since 2005 to monitor mother-to-child HIV transmission and perinatal antiretroviral toxicity.
EPHB4-related capillary malformation-arteriovenous malformation
CM-AVM2 (OMIM 618196), also called EPHB4-related capillary malformation-arteriovenous malformation, is a rare autosomal dominant vascular disorder from EPHB4 loss-of-function variants, mimicking CM-AVM1 and HHT.
Ephrin
Ephrins are membrane-bound ligands of Eph receptor tyrosine kinases, the largest RTK family, split into GPI-anchored ephrin-A and transmembrane ephrin-B classes mediating bidirectional signaling in axon guidance and cancer.
Epi Info
Epi Info is a free public domain software suite developed by the CDC for public health practitioners, widely used for outbreak investigations and surveillance since its 1985 release.
Epiblepharon
Epiblepharon is a congenital eyelid condition, common in East Asian children, in which a skin-muscle fold overrides the lower lid margin and turns lashes against the eye; it often resolves spontaneously and is corrected by the modified Hotz procedure.
Epibulbar choristoma
Epibulbar choristoma (ICD-11 LA14.06): benign congenital growth of normal tissue in an abnormal site on the eye surface; types include dermoid, dermolipoma, complex, and the rare osseous choristoma containing bone.
EPIC trial
EPIC (Early Psychosis: Investigating Cognition), NCT07196423, is a University of Nottingham, Wellcome Trust-funded trial testing glutamate measured with fMRS as a working memory marker in psychosis and a predictor of tDCS response, 106 participants, 2026-2027.
Epicanthic fold
Epicanthic fold (epicanthal fold, epicanthus, plica palpebronasalis): a skin fold of the upper eyelid covering the eye's inner corner. Normal in East Asians (40–90%) and children; also seen in Down syndrome and BPES; corrected by epicanthoplasty.
Epicardial mapping
Epicardial mapping is a cardiac electrophysiology procedure that records electrical activity from the heart's outer surface to locate arrhythmia sources, guiding catheter ablation of ventricular tachycardia.
Epicutaneous immunotherapy
Epicutaneous immunotherapy (EPIT) is a form of allergen immunotherapy in which allergen is applied daily through an adhesive skin patch, studied mainly for peanut and cow's milk allergy in children.
Epidemic
Epidemic: occurrence of disease cases clearly in excess of normal expectancy in a community or region; from Greek epi (upon) and demos (people). Distinct from outbreak (localized) and pandemic (several countries or continents).
Epidemic model
An epidemic model is a mathematical or computational representation of how an infectious disease spreads through a population, used to predict transmission dynamics and evaluate control interventions such as vaccination.
Epidemic myalgia
Epidemic myalgia, or Bornholm disease, devil's grip, epidemic pleurodynia (myalgia epidemica), is a febrile enteroviral illness, usually coxsackievirus B, causing severe pleuritic chest pain; first described on Bornholm in 1930 by Sylvest.
Epidemiological method
Epidemiological method: the systematic population-level approach of defining cases, counting and describing them by time, place, and person, calculating rates, and comparing groups; also called the epidemiologic approach, rooted in John Snow's 1854 cholera work.
Epidemiology
Epidemiology, often called the basic science of public health, studies how diseases and their causes are distributed across populations; John Snow's 1854 cholera investigation is its founding model.
Epidemiology and history of acute lymphoblastic leukemia
The epidemiology and history of acute lymphoblastic leukemia covers a cancer peaking at ages 1 to 4, transformed since 1948 from fatal to largely curable in children.
Epidemiology and risk factors of Hodgkin lymphoma
The epidemiology of Hodgkin lymphoma, a rare lymphatic cancer, features peaks in young adulthood and late life, with EBV, HIV, and family history as risk factors.
Epidemiology of endometriosis
The epidemiology of endometriosis describes how frequently the disease occurs, in whom, and which factors raise risk, with prevalence estimates contested between 1 and 10 percent.
Epidemiology of hemoglobinopathies
The epidemiology of hemoglobinopathies studies inherited hemoglobin disorders like sickle-cell disease and thalassemia, which about 5% of people carry and which malaria selection concentrated in the tropics.
Epidemiology of HIV/AIDS
Epidemiology of HIV/AIDS: global distribution, incidence, prevalence, and mortality of HIV infection and AIDS. 41.0 million people living with HIV in 2025, 1.2 million new infections, 570,000 deaths, concentrated in the WHO African Region and key populations.
Epidemiology of orofacial clefts
The epidemiology of orofacial clefts studies how often cleft lip and cleft palate occur, roughly 1 in 700 live births, with rates varying by region and ancestry.
Epidemiology of stroke
The epidemiology of stroke is the study of how stroke is distributed across populations; in 2021 it caused 11.9 million new strokes and 7.3 million deaths.
Epidemiology of syphilis
Epidemiology of syphilis: distribution and trends of Treponema pallidum infection. WHO estimates 8 million adult cases in 2022; resurgence since 2000 among MSM, with congenital syphilis rising sharply in the US and Europe.
Epidermal naevus
Epidermal naevus (epidermal nevus): benign overgrowth of the epidermis present at birth or early childhood, following Blaschko lines, caused by mosaic FGFR3, PIK3CA, or RAS mutations, sometimes syndromic.
Epidermal nevus syndrome
Epidermal nevus syndrome (ENS, Orphanet ORPHA:35125) is a group of rare mosaic disorders combining epidermal nevi with extracutaneous abnormalities of the brain, eyes, skeleton, and other systems, caused by postzygotic RAS-pathway mutations.
Epidermis
Epidermis: the outermost layer of skin, a keratinized stratified squamous epithelium with four or five strata, about 90% keratinocytes, thickness from 31 µm to 596.6 µm by body site, renewed every 28 to 50 days.
Epidermodysplasia verruciformis
Epidermodysplasia verruciformis (EV, Lewandowsky-Lutz disease) is a rare autosomal recessive genodermatosis causing beta-HPV susceptibility, flat warts, and 30-60% skin cancer risk, linked to TMC6/EVER1 or TMC8/EVER2 mutations.
Epidermoid cyst
Epidermoid cyst (epidermal inclusion cyst, follicular infundibular cyst), a benign keratin-filled skin cyst from the hair follicle infundibulum; not a sebaceous cyst; firm 1–3 cm nodule with central punctum, treated by complete excision.
Epidermolysis bullosa
Epidermolysis bullosa is a group of rare inherited skin disorders in which minor friction causes blisters, because structural proteins anchoring the skin layers are missing or defective.