25,729 articles
Formiminoglutamic aciduria
Formiminoglutamic aciduria, also called FTCD deficiency, is a rare inherited folate metabolism disorder causing buildup of FIGLU, with symptoms ranging from developmental delay to none.
Forodesine
Forodesine (BCX-1777, Immucillin H, Mundesine) is a transition-state analogue inhibitor of purine nucleoside phosphorylase for T-cell malignancies; approved in Japan 2017 for relapsed/refractory peripheral T-cell lymphoma, not elsewhere.
Fortis Healthcare
Fortis Healthcare Limited, an IHH Healthcare Berhad company, is a leading Indian integrated hospital and diagnostics provider: 36 facilities across 12 states, 6,150+ beds, Agilus Diagnostics, FY26 hospital revenue ₹7,773 crore.
FORWARD study
FORWARD study (NCT02592369): Medtronic-sponsored prospective single-arm registry of TAVR with the Evolut R valve in 1,040 real-world patients at 53 sites in 2016; 30-day mortality 1.9%, 1-year mortality 8.9%.
Fosamprenavir
Fosamprenavir (Lexiva, Telzir) is a prodrug of the HIV protease inhibitor amprenavir, approved by the FDA in 2003 and EMA in 2004; EU marketing was withdrawn in November 2025 and U.S. use is no longer common.
Fosaprepitant
Fosaprepitant (Ivemend, Emend for Injection) is an intravenous prodrug of the NK1 receptor antagonist aprepitant, converted within 30 minutes, used with a 5-HT3 antagonist and dexamethasone to prevent chemotherapy-induced nausea and vomiting in adults and children 6 months and older.
Fosbretabulin
Fosbretabulin (CA4P, ZYBRESTAT, combretastatin A4 phosphate) is an investigational vascular disrupting agent, a tubulin-binding prodrug from Combretum caffrum that collapses tumor blood vessels; trialed in thyroid, lung, and ovarian cancer without proven survival benefit.
Foscarnet
Foscarnet (trisodium phosphonoformate), sold as Foscavir, is an intravenous antiviral that blocks viral DNA polymerase and is used for CMV retinitis and resistant herpes infections.
Fosdenopterin
Fosdenopterin (Nulibry), synthetic cyclic pyranopterin monophosphate, is the first approved therapy for molybdenum cofactor deficiency type A, given as daily IV infusion; FDA approved February 2021, EMA September 2022, MHRA April 2024.
Fosfomycin
Fosfomycin (fosfomycin tromethamine, Monurol; IV form CONTEPO) is a phosphonate epoxide antibiotic inhibiting MurA cell wall synthesis, used as a single 3-g oral dose for uncomplicated UTI and intravenously for complicated UTI.
Fosgemcitabine palabenamide
Fosgemcitabine palabenamide (NUC-1031, Acelarin) is an investigational ProTide prodrug of gemcitabine for cancer, designed to bypass hENT1 transport, dCK activation, and CDA breakdown; its phase III biliary tract trial missed its survival endpoint.
Foshou San
佛手散 (Foshousan), also 芎归汤, a classic Chinese medicine formula first named in Xu Shuwei's 《普济本事方》 (c. 1132), of danggui and chuanxiong; a five-herb variant from 《妇人大全良方》 entered China's 2023 classic-formula catalog.
Fosinopril
Fosinopril (Monopril) is an ACE inhibitor prodrug converted to fosinoprilat, approved in 1991 for hypertension and adjunctive heart failure therapy; dosed 10-40 mg once daily, dual liver-kidney elimination, boxed fetal toxicity warning.
Foslevodopa
Foslevodopa (levodopa-4'-monophosphate, ABBV-951 with foscarbidopa; Vyalev, Produodopa) is a phosphate prodrug of levodopa given by continuous subcutaneous infusion for motor fluctuations in advanced Parkinson's disease.
Fosmetpantotenate
Fosmetpantotenate (RE-024) is a discontinued Retrophin phosphopantothenate prodrug for pantothenate kinase-associated neurodegeneration (PKAN); safe in the phase 3 FORT trial but failed to improve PKAN-ADL function.
Fosmidomycin
Fosmidomycin (FR-31564), a Streptomyces phosphonate antibiotic, inhibits DXR in the MEP isoprenoid pathway; an antimalarial drug lead with poor permeability, 3.5 h half-life, and no drug approval.
Fosnetupitant
Fosnetupitant (Akynzeo IV, with palonosetron) is a water-soluble phosphorylated prodrug of the NK1 receptor antagonist netupitant, given as a 235 mg intravenous infusion to prevent chemotherapy-induced nausea and vomiting; FDA approved 2018, noninferior to fosaprepitant with fewer injection-site reactions.
Fosphenytoin
Fosphenytoin (Cerebyx) is a water-soluble phosphate ester prodrug of phenytoin, dosed in phenytoin sodium equivalents, FDA-approved in 1996 for status epilepticus and neurosurgical seizures.
Fospropofol
Fospropofol, sold as Lusedra and formerly Aquavan, is a water-soluble prodrug of the anesthetic propofol used for sedation in adults during diagnostic or therapeutic procedures.
Fosrolapitant and palonosetron for injection
Fosrolapitant/palonosetron for injection (Ritanine, HR20013, 注射用磷罗拉匹坦帕洛诺司琼) is Hengrui's fixed-dose IV NK-1 plus 5-HT3 antiemetic, NMPA-approved May 27, 2025 for HEC-induced CINV, with a 188-hour rolapitant half-life allowing one dose per cycle.
Fossa ovalis (heart)
Fossa ovalis: oval depression on the lower interatrial septum of the right atrium, the closed remnant of the fetal foramen ovale; floor is septum primum, rim (limbus) is septum secundum; fusion fails in about 25% of people, leaving a patent foramen ovale.
Fostamatinib
Fostamatinib (Tavalisse, Tavlesse) is an oral SYK inhibitor approved in 2018 (US) and 2020 (EU) for chronic immune thrombocytopenia in adults after prior treatment failure; stable response 18% vs 2% placebo in phase 3 FIT trials.
Fostemsavir
Fostemsavir (Rukobia, BMS-663068) is a prodrug of temsavir, the first gp120-directed HIV-1 attachment inhibitor, FDA-approved in 2020 for multidrug-resistant HIV-1 in heavily treatment-experienced adults; 600 mg twice daily.
Fosun Yaopharma oral small-molecule GLP-1 receptor agonist (licensed to Pfizer)
YP05002, Fosun Yaopharma's oral small-molecule GLP-1 receptor agonist, is an experimental once-daily pill for weight management developed by YaoPharma, a Fosun Pharma subsidiary, and licensed exclusively to Pfizer in December 2025.
Fotagliptin benzoate (SAL067)
Fotagliptin benzoate (SAL067, FCN-005; trade name Xinliting, 信立汀) is a Chinese Category 1 DPP-4 inhibitor approved by NMPA in June 2024 for adult type 2 diabetes, dosed 12 mg once daily alone or with metformin, with compound patent to 2030.
Fotemustine
Fotemustine (Muphoran, S 10036) is a chloroethylating nitrosourea alkylating agent that crosses the blood-brain barrier; used in Europe for disseminated melanoma with brain metastases, recurrent glioblastoma, and primary CNS lymphoma, but not US-approved.
Foundation (cosmetics)
Foundation, also known as fond de teint, is a flesh-toned cosmetic applied to the face to even skin tone and conceal imperfections, sold as liquids, creams, and powders.
Four square step test
The four square step test (FSST) is a timed clinical test of dynamic standing balance in which the patient steps over four canes in a cross pattern.
Four Volumes of Nectar
四部甘露 (Four Volumes of Nectar, 甘露四部, 都德泽西): four 18th-century medical treatises by the Mongolian physician Ishbaljir (1704–1788), a foundational classic of Mongolian medicine integrating the Tibetan Four Tantras with cold-heat pattern diagnosis.
Four-dimensional computed tomography
Four-dimensional computed tomography is a CT acquisition and reconstruction method that resolves a scanned volume over the respiratory cycle, used mainly for radiation therapy planning of breathing tumors.