25,729 articles
Maternal phenylketonuria syndrome
Maternal phenylketonuria syndrome (maternal PKU syndrome, MPKUS) is a pattern of birth defects in babies of pregnant women with PKU, caused by high phenylalanine crossing the placenta.
Maternal serum screening
Maternal serum screening is a blood test performed during pregnancy that measures fetal and placental proteins to estimate the risk of chromosomal abnormalities and open neural tube defects.
Maternal uniparental disomy of chromosome 20 syndrome
Maternal uniparental disomy of chromosome 20 syndrome (UPD(20)mat, Mulchandani-Bhoj-Conlin syndrome): a very rare imprinting disorder where both chromosome 20 copies come from the mother, causing IUGR, short stature, and severe feeding difficulties.
Maternity Hospitals
Maternity hospitals, historically called lying-in hospitals, are hospitals specializing in care for women during pregnancy and childbirth. Key facts: Göttingen 1751 origin, rooming-in, birth center alternatives, US rural ward closures.
Matlazahuatl epidemic
The matlazahuatl epidemic of 1736–1739 was an outbreak of epidemic typhus that began in Tacuba and swept the Viceroyalty of New Spain, killing more than 40,000 people in Mexico City alone.
Matrix Bands
Matrix bands are thin metal or plastic walls placed around a tooth during Class II dental restorations to shape proximal contours and contacts; circumferential (Tofflemire) and sectional systems are the main types, with sectional favored for composites.
MATRIX trial (NCT01433627)
MATRIX (NCT01433627), Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of AngioX, a three-trial European randomized program in acute coronary syndrome: radial vs femoral access, bivalirudin vs heparin, and bivalirudin infusion duration.
Matrix-induced autologous chondrocyte implantation
Matrix-induced autologous chondrocyte implantation (MACI) is a two-stage cartilage repair technique in which a patient's own cultured chondrocytes are implanted on a collagen membrane, mainly for knee defects.
Matrix-M
Matrix-M is a saponin-based vaccine adjuvant developed by Novavax, composed of 40-nm cage-like nanoparticles from soapbark tree saponins; it boosts immune responses in Nuvaxovid and the R21/Matrix-M malaria vaccine.
Matthew Bush
Matthew L. Bush is an American otolaryngologist and hearing-health researcher who chairs Otolaryngology at the University of Kentucky and received a 2025 Presidential Early Career Award.
Matthew Klaric
Matthew Klaric is an American computer scientist serving as Chief Data Scientist of the National Geospatial-Intelligence Agency since September 2023, known for satellite-image retrieval research and early Project Maven funding work.
Matthew Laurens
Matthew Laurens is an American pediatric infectious diseases researcher at the University of Maryland's Center for Vaccine Development, director of the Typhoid Vaccine Acceleration Consortium.
Matthew Wheeler
Matthew Wheeler is an American biostatistician at NIOSH, part of the CDC, who received the 2014 Presidential Early Career Award for improving exposure-response modeling in occupational risk assessment.
Matthew-Wood syndrome
Matthew-Wood syndrome (PDAC syndrome, Spear syndrome, MCOPS9, OMIM 601186) is an ultra-rare genetic congenital malformation syndrome with bilateral anophthalmia or microphthalmia plus pulmonary hypoplasia, diaphragmatic hernia, and cardiac defects, usually autosomal recessive from STRA6 or RARB mutations and mostly lethal.
Maturity-onset diabetes of the young
MODY, maturity-onset diabetes of the young, is the most common monogenic diabetes: autosomal dominant, early onset before 25-30, 14 gene subtypes (GCK, HNF1A, HNF4A), often misdiagnosed as type 1 or 2.
Maureen Bisognano
Maureen Bisognano is an American healthcare quality improvement leader who led the Institute for Healthcare Improvement as President and CEO from 2010 to 2015 and is a member of the National Academy of Medicine.
Maurice Wood
Maurice Wood (1922–2016) was a British-born physician and primary care researcher who founded NAPCRG and co-authored the 1976 Virginia Study at the Medical College of Virginia.
Mauthner neuron
Mauthner neuron (Mauthner cell, M-cell): a pair of giant reticulospinal hindbrain neurons in fishes and amphibians that triggers the C-start escape response, with ~100 μm somata, segregated sensory dendrites, and mixed electrical-chemical synapses.
Mavacamten
Mavacamten (Camzyos, MYK-461), a first-in-class oral cardiac myosin inhibitor by MyoKardia/Bristol Myers Squibb, FDA-approved 28 April 2022 for symptomatic obstructive hypertrophic cardiomyopathy; proven in EXPLORER-HCM, not in nonobstructive HCM.
MAVAN study
MAVAN (Maternal Adversity, Vulnerability and Neurodevelopment) is a Canadian prospective birth cohort of about 578-590 mother-child dyads recruited 2003-2009 in Montreal and Hamilton, studying prenatal adversity, gene-environment interaction, and child mental health, with the MAVAN-R adult follow-up at age 22.
Mavorixafor
Mavorixafor (XOLREMDI) is an oral CXCR4 antagonist approved in 2024 for WHIM syndrome in patients 12 and older, and EU-approved in 2026; in phase 3 development for chronic neutropenia (4WARD trial).
Max Gerson
Max Gerson (1881–1959), German-born physician, developed the Gerson therapy, an alternative cancer treatment of vegetarian diet, supplements, and coffee enemas; rejected by NCI reviews and unproven in controlled trials.
Max Jacobson
Max Jacobson (1900-1979), "Dr. Feelgood" or "Miracle Max," German-born New York physician whose amphetamine-laced injections treated celebrities and JFK, including the 1961 Vienna summit; his license was revoked in 1975 and he died in 1979.
Max Michael Jr
Max Michael Jr was a physician and medical educator who served as the first dean of the University of Florida College of Medicine's Jacksonville campus, from 1962 to 1985.
Max T. Weiss
Max T. Weiss (Max Tibor Weiss, 1922–2006) was a Hungarian-born American engineer and physicist elected to the National Academy of Engineering in 1986 for ferrite microwave research.
Maxacalcitol
Maxacalcitol (マキサカルシトール), or 22-oxacalcitriol, is a Japanese vitamin D3 analog, brand Oxarol, used intravenously for secondary hyperparathyroidism in dialysis and topically for psoriasis.
Maxilla
Maxilla: paired midfacial bone formed by fused right and left maxillary bones; carries upper teeth, forms orbital floor and hard palate, houses the largest paranasal sinus; key in Le Fort fractures and sinus lift implant surgery.
Maxillary nerve
Maxillary nerve (V2), middle purely sensory division of the trigeminal nerve; exits via foramen rotundum to the pterygopalatine fossa, ends as the infraorbital nerve, and supplies midface, upper teeth, palate, and nasal mucosa.
Maxillary osteotomy
A maxillary osteotomy cuts and repositions the upper jaw bone to correct jaw deformities, malocclusion, and obstructive sleep apnea, most often via the Le Fort I osteotomy.
Maxillary sinus
Maxillary sinus (antrum of Highmore): the largest paranasal sinus, a pyramid-shaped air cavity in the maxilla draining via a superiorly placed ostium into the middle meatus; first to develop, closely related to upper teeth and sinus lift surgery.