25,729 articles
Non-syndromic unicoronal craniosynostosis
Non-syndromic unicoronal craniosynostosis, or unilateral coronal synostosis, is premature fusion of one coronal suture, occurring in about 1/10,000 births, causing facial scoliosis, strabismus, and amblyopia, treated by endoscopic strip craniectomy or fronto-orbital advancement.
Non-terminal myelocystocele
Non-terminal myelocystocele (ORPHA:645340), a rare closed spinal dysraphism above the conus with a skin-covered CSF sac; abortive and complete subtypes; favorable prognosis versus myelomeningocele.
Non-thrombocytopenic purpura
Non-thrombocytopenic purpura (ICD-11 3B60; ICD-10-CM D69.2) is skin or mucous-membrane bleeding with a normal platelet count, caused by vascular, drug, congenital, or vitamin C deficiency factors, including senile purpura.
Non-tuberculous mycobacterial lymphadenitis
Non-tuberculous mycobacterial lymphadenitis (NTM cervicofacial lymphadenitis, scrofula-like adenitis): chronic painless neck node infection in children 1-5, mainly MAC and M. lentiflavum; complete excision cures 98% but risks facial palsy.
Nonacog beta pegol
Nonacog beta pegol (N9-GP; Rebinyn, Refixia) is Novo Nordisk's glycoPEGylated extended half-life recombinant factor IX for hemophilia B, with a 40 kDa PEG on the activation peptide, ~107–111 h half-life, FDA-approved 2017.
Nonallergic rhinitis
Nonallergic rhinitis (NAR), also called nonallergic rhinopathy or vasomotor rhinitis, is chronic nasal congestion, rhinorrhea, and sneezing without allergen sensitization or infection; diagnosed by exclusion with negative allergy tests, treated with intranasal corticosteroids, antihistamines, ipratropium, or nerve ablation.
Nonbenzodiazepine
Nonbenzodiazepines (Z-drugs): zolpidem, zaleplon, eszopiclone, zopiclone; sedative-hypnotics acting at the GABA-A benzodiazepine site for insomnia, with alpha-1 selectivity, 2019 FDA boxed warning for complex sleep behaviors, and less dependence risk than benzodiazepines.
Noncardiac influences on heart rate
Noncardiac influences on heart rate are systemic and environmental factors, including body temperature, sleep, posture, altitude, emotion, and caffeine, that change heart rate without any fault in the heart itself.
Noncompaction cardiomyopathy
Noncompaction cardiomyopathy (left ventricular noncompaction, LVNC, hypertrabeculation) is a spongy-myocardium condition with prominent trabeculae and deep recesses; diagnosed by NC/C ratios on echo or CMR, genetically overlapping other cardiomyopathies, with outcomes similar to dilated cardiomyopathy.
Noncyclic pelvic pain
Noncyclic pelvic pain (ICD-11 GA34.21) is chronic pelvic pain in women not tied to the menstrual cycle, located in the pelvis, abdominal wall, lower back, or buttocks; prevalence estimates range widely and treatment evidence is limited.
None used on labelling for supply through UN agencies. Also marketed with labelled commercial name BE Td
WHO-prequalified diphtheria-tetanus (dT) vaccine, product FVP-P-399, by Biological E. Limited, India, marketed as BE Td; unbranded 20-dose vials for UN agency supply, prequalified 9 March 2020 under CDSCO oversight.
None used on labelling for supply through UN agencies. Also marketed with labelled commercial name ComBE Five.
ComBE Five (Liquid) is a WHO-prequalified liquid pentavalent DTP-HepB-Hib vaccine from Biological E. Limited, India, prequalified 27 November 2014, given intramuscularly to infants from 6 weeks of age.
None used on labelling for supply through UN agencies. Also marketed with labelled commercial name TRIPVAC
TRIPVAC is Biological E. Limited's WHO-prequalified whole-cell DTP vaccine (effective 31 July 2014), unlabelled for UN agency supply, liquid single-dose vials, thiomersal-preserved, stored 2-8°C; two lots were banned in Ukraine in 2026.
Nonfluoride enamel opacities
Nonfluoride enamel opacities are developmental enamel defects, white to yellow-brown areas of altered translucency not caused by fluoride, occurring in low-fluoride areas; ICD-11 code DA07.1; MIH is the main modern subset.
Nonheme iron
Nonheme iron is dietary iron not bound in a heme ring, found in plant foods, fortified products, and meat, with absorption strongly shaped by other meal components.
Noninfectious intermediate uveitis
Noninfectious intermediate uveitis, also called pars planitis when idiopathic, is chronic inflammation of the vitreous, pars plana, and peripheral retina; treated with corticosteroids, immunosuppressants, and adalimumab.
Noninvasive prenatal testing
Noninvasive prenatal testing, also known as Noninvasive Prenatal Screening, is a maternal blood test that screens for fetal chromosomal abnormalities. It is a screening test, not a diagnostic one.
Nonivamide
Nonivamide (pseudocapsaicin, N-vanillylnonanamide, CAS 2444-46-4) is a synthetic capsaicinoid, the amide of vanillylamine and nonanoic acid, a TRPV1 agonist used in pepper sprays, topical rubefacients, and as a flavoring.
Nonorganic visual loss
Nonorganic visual loss, also called functional visual loss, is reduced visual acuity or field with no organic lesion found, accounting for about 12% of neuro-ophthalmology diagnoses.
Nonoxynol-9
Nonoxynol-9 (N-9), a detergent spermicide in OTC vaginal contraceptives like Conceptrol and VCF, kills sperm by disrupting membranes but failed as an HIV microbicide and is not recommended for STI prevention.
Nonproliferative diabetic retinopathy
Nonproliferative diabetic retinopathy (NPDR) is the early stage of diabetic retinopathy, marked by microaneurysms, hemorrhages, exudates, IRMA, and venous beading without neovascularization, staged mild, moderate, or severe.
Nonpurulent mastitis associated with childbirth
Nonpurulent mastitis associated with childbirth, also called lactation or puerperal mastitis, is ICD-11 code JB45.1 and ICD-10-CM O91.2: breast inflammation without pus during pregnancy, the 42-day puerperium, or lactation.
Nonrheumatic aortic valve stenosis
Nonrheumatic aortic valve stenosis (ICD-11 BB70.1, ICD-10 I35.0) is aortic valve narrowing from non-rheumatic causes, chiefly calcific degeneration and bicuspid valve, the most common valvular heart disease in adults over 65, treated by SAVR or TAVR.
Nonspecific intraventricular conduction delay
Nonspecific intraventricular conduction delay (NICD, NSIVCD): an ECG finding of prolonged QRS (over 110 ms in adults) without LBBB or RBBB criteria; causes, prognosis, and CRT implications.
Nonspecific low blood-pressure reading
Nonspecific low blood-pressure reading is a clinical finding of a blood pressure of 90/60 mmHg or lower without a diagnosis of hypotension, coded R03.1 in ICD-10-CM.
Nonspecific mesenteric lymphadenitis
Nonspecific mesenteric lymphadenitis, also called primary mesenteric adenitis, is a self-limiting inflammation of the abdominal lymph nodes draining the intestine that mainly affects children and mimics appendicitis.
Nonsteroidal anti-inflammatory drug
Nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, ibuprofen, naproxen, diclofenac, and celecoxib, relieve pain, inflammation, and fever by inhibiting COX-1 and COX-2 enzymes; key risks are gastrointestinal bleeding, kidney injury, and cardiovascular events.
Nonstress test
Nonstress test (NST), a third-trimester antenatal fetal surveillance test recording fetal heart rate for 20+ minutes; reactive if two or more accelerations occur, with ~99.5-99.8% negative predictive value but ~50% false-positive nonreactive rate.
Nonsurgical periodontal therapy
Nonsurgical periodontal therapy (NSPT) treats periodontitis by removing plaque and calculus above and below the gumline, mainly through scaling and root planing, without cutting gum tissue.
Nonsynaptic plasticity
Nonsynaptic plasticity: activity- or learning-induced changes in neuronal intrinsic excitability, ion channels, myelin, and homeostatic or metaplastic mechanisms, rather than synaptic strength; includes intrinsic plasticity, slow AHP reductions, and transient excitability-based memory traces.