25,729 articles
A Place at the Table
A Place at the Table is a 2013 American documentary on hunger in the United States, directed by Kristi Jacobson and Lori Silverbush, released by Magnolia Pictures after its 2012 Sundance premiere as Finding North; distinct from unrelated films and a 2020 novel of similar titles.
A-172
A-172 (A172, CVCL_0131, ATCC CRL-1620) is a human glioblastoma cell line from a 53-year-old male, PTEN-deleted, IDH1-wildtype, MSS, adherent with epithelial-like morphology, doubling time about 26-48 hours.
A-TC7 trial
A-TC7 (NCT04513002, A-T2020/01) was a Phase 2a/b placebo-controlled dose-escalation trial of triheptanoin for ataxia-telangiectasia in Brisbane, 31 participants, 2022-2023, showing reduced nasal epithelial cell death and improved ataxia scales.
A. Alan Fischer
A. Alan Fischer (1926–2007) was an American family medicine physician and educator who founded family medicine at Indiana University and in 1971 became the first Indiana physician appointed to the Institute of Medicine.
A/WySn
A/WySn (A/WySnJ) is an inbred mouse substrain of strain A, passed from Strong to Snell by 1951, known for 20-30% spontaneous cleft lip from the clf1 and clf2 loci and, in A/WySnJ, B cell deficiency from the Tnfrsf13c^bcmd1 BAFF-R mutation.
A1chieve® study
A1chieve (A1chieve® study) was a Novo Nordisk-sponsored 24-week observational study of 66,726 people with type 2 diabetes starting insulin detemir, biphasic insulin aspart 30, or insulin aspart across 28 non-Western and other countries.
A2ALL-1 study
A2ALL-1 (Adult-to-Adult Living Donor Liver Transplantation Cohort Study), NCT00096733: nine-center NIH consortium launched 2002 comparing living vs deceased donor liver transplant outcomes; 1,603 participants, 385-recipient early report, learning curve and risk factors.
A2ALL-2 study
A2ALL-2 (Adult-to-Adult Living Donor Liver Transplantation Cohort Study 2), NCT01619475, was the second NIDDK-funded cycle of the A2ALL consortium: nine North American transplant centers with a University of Michigan data center, studying donor psychosocial, financial, and recipient graft outcomes of living liver donation, 2011–2014.
A4 trial
The A4 trial (Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease) was a Phase 3, placebo-controlled trial of solanezumab in 1,169 amyloid-positive, cognitively unimpaired adults 65-85; it showed no cognitive benefit over 240 weeks.
A400 (RET inhibitor, KL590586)
A400 (KL590586, EP0031, lunbotinib) is an oral next-generation selective RET inhibitor from Kelun-Biotech and Ellipses Pharma for RET-altered cancers, with phase II NSCLC ORR of 81-87% and an NMPA filing in 2025.
AA amyloidosis
AA amyloidosis, or secondary amyloidosis, is a systemic disease where serum amyloid A (SAA) fibrils from chronic inflammation deposit mainly in kidneys; diagnosis by Congo red biopsy and SAP scintigraphy, treated by suppressing inflammation.
Aafia Siddiqui (عافیہ صدیقی)
Aafia Siddiqui (عافیہ صدیقی), Pakistani neuroscientist with MIT and Brandeis degrees, convicted in 2010 of attempted murder of US officers and sentenced to 86 years; her 2003-2008 disappearance and jihadi hostage demands make her case singular.
AAIHINNN study
AAIHINNN (NCT06168838), Anticoagulant-associated Intracranial Hemorrhage, is a retrospective single-center observational study at Mexico's INNN Manuel Velasco Suárez covering 2015-2023, targeting 1,200 patients to measure incidence, prevalence, mortality, and treatment patterns of anticoagulant-related intracranial bleeding.
AAIMASP trial
AAIMASP (Get Going, NCT02635477) was an American College of Cardiology fellows-led multicenter randomized trial testing an adaptive accelerometer step-counter bracelet versus a monitor-only device to raise daily steps in frail adults 70+ in the 30 days after cardiovascular hospitalization; registry status unknown, no results posted.
AApoAIV amyloidosis
AApoAIV amyloidosis (apolipoprotein A-IV amyloidosis) is a rare acquired systemic amyloidosis from wild-type ApoA-IV, causing medullary renal amyloid with minimal proteinuria, progressive CKD, and cardiac disease; typed by mass spectrometry.
Aarhus University Hospital
Aarhus University Hospital (Aarhus Universitetshospital, AUH) is a 528,000 m² university hospital in Skejby, Aarhus, Denmark, formed by the 2011 merger of Skejby and Aarhus Sygehus, with 840 beds and about 9,300 full-time staff.
Aarogya Setu (आरोग्य सेतु)
Aarogya Setu (आरोग्य सेतु) is India's government COVID-19 contact tracing app launched 2 April 2020, using Bluetooth and GPS, with over 114 million users by May 2020, open-sourced under Apache 2.0, criticized for privacy issues, and repurposed in 2026 as Aarogya Setu 2.0, a National Health Authority personal health record app.
Aarskog-Scott syndrome
Aarskog-Scott syndrome (faciogenital dysplasia, Aarskog syndrome) is a rare X-linked recessive developmental disorder caused by FGD1 variants, with hypertelorism, short stature, shawl scrotum, and brachydactyly; prevalence about 1/25,000, no genotype-phenotype correlation.
ABACUS trial
ABACUS trial (NCT03145285), an Italian phase 2 open-label study of abiraterone acetate for Cushing's syndrome in adrenocortical carcinoma; two cohorts, 10 planned patients, UFC normalization endpoint.
Abagovomab
Abagovomab (ACA125, VaccinOvar) is a murine IgG1 anti-idiotype monoclonal antibody vaccine mimicking the CA-125 (MUC16) epitope, developed as ovarian cancer maintenance immunotherapy; immunogenic but failed the phase III MIMOSA trial.
Abaloparatide
Abaloparatide (Tymlos, Eladynos), a PTHrP(1-34) analog PTH1-receptor agonist, is an anabolic osteoporosis drug given as 80 mcg daily subcutaneous injection, FDA-approved 2017, EU 2022.
Abametapir
Abametapir (HA-44, Xeglyze/XEGLYZE) is a 5,5'-dimethyl-2,2'-bipyridine metalloproteinase-inhibitor pediculicide; a 0.74% lotion FDA-approved in 2020 for single-application head lice treatment.
Abarelix
Abarelix (Plenaxis), a GnRH antagonist by Praecis, gave injection-based testosterone suppression without surge for advanced prostate cancer; FDA approved November 25, 2003 with restricted distribution, withdrawn from the US market after anaphylaxis risk.
Abatacept
Abatacept (Orencia) is a CTLA-4-Ig fusion protein, the first selective T-cell costimulation modulator, FDA-approved in 2005 for rheumatoid arthritis and later for juvenile idiopathic arthritis, psoriatic arthritis, and graft-versus-host disease prophylaxis.
Abbott Laboratories
Abbott Laboratories (ABT), founded 1888 by Wallace Calvin Abbott in Chicago, is a diversified healthcare company in medical devices, diagnostics, nutrition (Similac, Ensure, FreeStyle Libre), and branded generics, with 2025 sales of $44.3 billion.
Abbreviated breast MRI
Abbreviated breast MRI is a shortened MRI protocol for breast cancer screening, developed for women with dense breasts, cutting scan time from 17 to 3 minutes.
Abbreviated Injury Scale
The Abbreviated Injury Scale (AIS) is an anatomical coding system that grades each individual injury from 1 (minor) to 6 (maximal) across nine body regions.
AbbVie
AbbVie Inc. is an American research-based biopharmaceutical company headquartered in North Chicago, Illinois. Formed by Abbott Laboratories' 2013 spinoff, it is known for Humira and acquired Allergan in 2020.
Abby and Brittany Hensel
Abby and Brittany Hensel (Abigail and Brittany Lee Hensel, born 1990) are American dicephalic parapagus conjoined twins, two heads on one torso, unseparated, Minnesota teachers; Abby married Josh Bowling in 2021.
ABC (medicine)
ABC (Airway, Breathing, Circulation) is the emergency-medicine priority mnemonic, extended to ABCDE with Disability and Exposure; cardiac arrest CPR switched from ABC to CAB in 2010, with trauma and drowning exceptions.