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Transtympanic Micropressure Treatment
Transtympanic micropressure treatment (Meniett therapy, positive pressure therapy) delivers 5–20 cmH2O air pressure pulses to the middle ear via a tympanostomy tube to treat Ménière's disease vertigo; RCT evidence shows no benefit over placebo.
Transurethral resection
Transurethral resection is an endoscopic operation that cuts away bladder tumors or prostate adenoma with a wire loop passed through the urethra inside a resectoscope.
Transurethral Resection of Bladder
Transurethral resection of bladder tumor (TURBT) is the standard endoscopic procedure to diagnose, stage, and treat bladder cancer via the urethra, using a resectoscope; key quality markers are detrusor muscle sampling, repeat resection within six weeks when needed, and immediate intravesical chemotherapy.
Transurethral resection of the prostate
Transurethral resection of the prostate (TURP) is the endoscopic removal of obstructing prostate tissue via a wire-loop resectoscope through the urethra, done for BPH-related urinary obstruction. Introduced by Stern in 1926, it remains a benchmark surgical BPH treatment alongside HoLEP and GreenLight laser.
Transurethral ultrasound ablation
Transurethral ultrasound ablation (TULSA) is a minimally invasive treatment that destroys prostate tissue with directional ultrasound from a rotating urethral applicator, guided in real time by MRI thermometry.
Transvenous lead extraction
Transvenous lead extraction is a catheter-based procedure that removes pacemaker or defibrillator leads through the veins, mainly for infection, with complete success above 95% and major complications near 1%.
Transvenous pacing
Transvenous pacing is a temporary procedure in which a pacing catheter passed through a vein into the right ventricle delivers electrical impulses to maintain heart rate in bradyarrhythmias.
Transverse abdominal muscle
Transversus abdominis (TrA, TVA), the deepest anterolateral abdominal wall muscle; transverse fibers compress viscera, raise intra-abdominal pressure, and tense the linea alba, central to trunk stabilization, DRA rehabilitation, and the TAP block.
Transverse myelitis
Transverse myelitis (TM), also called acute or idiopathic transverse myelitis, is spinal cord inflammation damaging myelin, causing weakness, sensory loss, and bladder dysfunction below a band-like level; about 1,400 new US cases yearly, treated with IV steroids and plasma exchange.
Transversus abdominis plane block
The transversus abdominis plane block, or TAP block, is a regional anesthesia technique that relieves pain after abdominal surgery by injecting local anesthetic into the abdominal wall.
Trapeziectomy
Trapeziectomy is a hand surgical procedure that removes the trapezium, one of the wrist's carpal bones, to relieve pain from arthritis at the base of the thumb.
Trapeziometacarpal osteoarthritis
Trapeziometacarpal osteoarthritis (basal joint or rhizarthrosis, thumb CMC1 arthritis): degenerative arthritis of the thumb base, common in postmenopausal women, treated first with splints, exercises, NSAIDs, and injections, then trapeziectomy or other surgery.
Trapezius
Trapezius: large triangular back muscle from occiput to T12 inserting on clavicle, acromion, and scapular spine; upper, middle, lower parts; innervated by spinal accessory nerve (CN XI); palsy causes lateral scapular winging.
TRAPPC11-related limb-girdle muscular dystrophy R18
TRAPPC11-related limb-girdle muscular dystrophy R18 (LGMD2S, OMIM 615356) is a rare autosomal recessive muscular dystrophy from TRAPPC11 mutations, causing proximal weakness, intellectual disability, hyperkinetic movements, liver disease, and alpha-dystroglycan hypoglycosylation.
TraQ trial
TraQ trial (NCT05085808), a withdrawn phase 4 USC pilot randomized trial comparing trazodone, quetiapine, and placebo for ICU delirium in surgical ICU patients at Keck Hospital; planned 30 patients, primary outcome delirium duration by CAM-ICU.
TRAS study
TRAS study (NCT04225338) is a retrospective cohort study at Brazil's Federal University of São Paulo evaluating 8-year mortality and graft failure after percutaneous intervention for transplant renal artery stenosis.
Trastuzumab
Trastuzumab (Herceptin) is a humanized anti-HER2 monoclonal antibody from Genentech, FDA-approved in 1998 for HER2-positive breast cancer and later gastric cancer, with biosimilars and ADC derivatives now in wide use.
Trastuzumab botidotin for injection
Trastuzumab botidotin (博度曲妥珠单抗, A166, brand Shutaile) is a Kelun-Biotech HER2-targeting antibody-drug conjugate with a Duo-5 (MMAF-derivative) payload, DAR 2, approved by China's NMPA in October 2025 for previously treated HER2-positive metastatic breast cancer.
Trastuzumab brengitecan
Trastuzumab brengitecan (T-Bren, BL-M07D1) is a Sichuan Baili HER2-directed antibody-drug conjugate using the Ed-04 topoisomerase I inhibitor payload, GGFG cathepsin B-cleavable linker, and DAR 8, in phase 3 breast cancer trials.
Trastuzumab deruxtecan
Trastuzumab deruxtecan (Enhertu, T-DXd, DS-8201a) is a HER2-directed antibody-drug conjugate linking trastuzumab to the topoisomerase I inhibitor DXd, approved for HER2-positive, HER2-low, and HER2-mutant cancers.
Trastuzumab duocarmazine
Trastuzumab duocarmazine (SYD985, T-Duo, Jivadco) is a HER2-targeted antibody-drug conjugate linking trastuzumab to the duocarmycin prodrug seco-DUBA; it met PFS endpoint in the TULIP phase III trial but its EMA application was withdrawn.
Trastuzumab emtansine
Trastuzumab emtansine (T-DM1, Kadcyla), an antibody-drug conjugate of trastuzumab and the tubulin inhibitor DM1; first ADC approved for a solid tumor (2013) for HER2-positive breast cancer.
Trastuzumab envedotin
Trastuzumab envedotin (DP303c) is a CSPC-developed HER2-targeted antibody-drug conjugate: trastuzumab-sequence IgG1 with site-specific MMAE conjugation (DAR 2.0), phase 3 PFS 8.8 vs 5.8 months versus T-DM1 in HER2-positive advanced breast cancer.
Trastuzumab pamirtecan
DB-1303 (trastuzumab pamirtecan, BNT323) is DualityBio's third-generation HER2-targeting antibody-drug conjugate with a topoisomerase I inhibitor payload; its Phase 3 breast cancer trial met its PFS endpoint and China's NMPA accepted its BLA in 2026.
Trastuzumab regimen
A trastuzumab regimen is a cancer treatment pairing trastuzumab, a monoclonal antibody against the HER2 receptor, with chemotherapy, used mainly in HER2-positive breast and gastric cancers.
Trastuzumab vedotin
Trastuzumab vedotin (MRG002) is an investigational HER2-targeting antibody-drug conjugate: fucosylated trastuzumab (MAB802) linked to MMAE via a Val-Cit linker, DAR 3.8, in phase I/II trials for HER2-positive and HER2-low breast and gastric cancers.
Trauma center
Trauma center: hospital specialized in definitive care of severely injured patients, classified ACS Levels I-V, designated by states and verified by the ACS; first U.S. centers opened 1966, Shock Trauma Center 1969.
Trauma laparotomy
Trauma laparotomy is an emergency operation in which the abdomen is opened to find and repair life-threatening internal injuries after blunt or penetrating trauma, the standard of care for unstable patients.
Trauma team activation
Trauma team activation (TTA) is a hospital protocol that summons a designated trauma team before or upon arrival of a patient with suspected major trauma.
Trauma-sensitive yoga
Trauma-sensitive yoga is yoga adapted for trauma survivors, using gentle Hatha-based practice, invitational language, and participant choice; a 2014 trial found it reduced PTSD symptoms.