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CAMKK2

CAMKK2 (CaMKK2, CaMKKβ; gene ID 10645, HGNC:1470) is a human calcium/calmodulin-dependent serine/threonine kinase kinase that activates CaMK1, CaMK4, and AMPK, regulates brain function and energy metabolism, and is linked to bipolar disorder and prostate cancer.

Camlipixant

Camlipixant (BLU-5937, GSK5464714) is GSK's investigational selective P2X3 receptor antagonist for refractory chronic cough, developed by BELLUS Health; SOOTHE phase 2b cut cough frequency ~34%, but CALM-2 phase 3 missed its endpoint.

CAMOS syndrome

CAMOS syndrome, also known as SCAR5, is a rare autosomal recessive disorder causing congenital ataxia, severe intellectual disability, optic atrophy, and skin vessel abnormalities, described in five children from a Lebanese family.

Camostat

Camostat (camostat mesilate, also FOY-305, sold as Foipan) is a synthetic serine protease inhibitor approved in Japan and South Korea for chronic pancreatitis and postoperative reflux esophagitis.

Camouflage

Camouflage: biological concealment via crypsis (background matching), disruptive coloration, and masquerade (misidentification as inedible objects). Covers moving-target effects, chemical crypsis, terminology, and climate-driven camouflage mismatch in stoats and hares.

CAMP trial

The Childhood Asthma Management Program (CAMP) trial was an NHLBI-sponsored multicenter randomized trial in 1,041 children aged 5-12 with mild-to-moderate asthma, testing budesonide, nedocromil, or placebo plus albuterol; neither drug improved lung growth, budesonide improved control, and a small persistent height reduction occurred.

Campanula

Campanula (bellflowers), genus of Campanulaceae herbs with bell-shaped five-lobed flowers, native across the Northern hemisphere; about 455 species, polyphyletic in molecular phylogenies, including rampion and Canterbury bells.

Campanula rapunculoides

Campanula rapunculoides, creeping or rampion bellflower, a rhizomatous perennial bellflower native to Europe and Central Asia, invasive in North America, producing up to 15,000 seeds yearly.

Campanula rapunculus

Campanula rapunculus (rampion, rampion bellflower) is a biennial Campanulaceae native from Europe to Iran, once grown for its edible turnip-like roots and linked to the Rapunzel tale; not the invasive Campanula rapunculoides.

Campanula rotundifolia

Campanula rotundifolia, the harebell or common harebell (bluebell in Scotland), is a rhizomatous perennial bellflower native from Europe to the Russian Far East, a polyploid complex (2n = 34, 68, 102) of grasslands, heaths, and dunes, self-incompatible and bee pollinated.

Campanulaceae

Campanulaceae (bellflower family) is a cosmopolitan family of about 84 genera and 2,319 species in the order Asterales, including Campanula, Lobelia, Codonopsis and Platycodon, with milky latex, inferior ovaries and secondary pollen presentation.

Campbell W. McMillan

Campbell W. McMillan (1927–2008) was an American pediatric hematologist at UNC Chapel Hill who co-led the first human trial of genetically engineered recombinant factor VIII in 1987.

Camphechlor

Camphechlor, also called toxaphene (CAS 8001-35-2), is a mixture of chlorinated camphenes used as an organochlorine insecticide, mainly on cotton; the most heavily used US insecticide in 1975, banned there in 1990.

Campomanesia

Campomanesia Ruiz & Pav. is a South American genus of about 43-45 woody Myrtaceae species in tribe Myrteae, recognized by a 4-18-locular ovary and a glandular false seed coat; includes guabiroba (C. xanthocarpa) and cambuci (C. phaea).

Campomelia, Cumming type

Campomelia, Cumming type (Cumming syndrome, OMIM 211890, ORPHA1318) is an autosomal recessive lethal congenital disorder with bowed long bones in all four limbs plus polycystic kidneys, polysplenia, cervical lymphocele, and other multivisceral anomalies.

Campomelic dysplasia

Campomelic dysplasia (CD), also called campomelic dwarfism, is a rare autosomal dominant SOX9-related skeletal dysplasia with bowed long bones, Pierre Robin sequence, 11 rib pairs, and frequent 46,XY sex reversal; about 10% survive the neonatal period.

Camptodactyly of fingers

Camptodactyly of fingers is a rare genetic condition in which a finger, usually the little finger, is permanently bent at the middle joint and cannot fully straighten.

Camptodactyly-tall stature-scoliosis-hearing loss syndrome

CATSHL syndrome (camptodactyly-tall stature-scoliosis-hearing loss syndrome, OMIM 610474) is a rare FGFR3 loss-of-function disorder causing finger contractures, overgrowth, scoliosis, and sensorineural hearing loss.

Camptonectes

Camptonectes is an extinct genus of scallop-like pectinid bivalves (Agassiz in Meek, 1864; type species Pecten lens), known from Permian to Miocene marine fossils worldwide, including Jurassic Sundance Seaway and Late Maastrichtian Patagonian species.

Camptothecin

Camptothecin (CPT), a pentacyclic quinoline alkaloid from Camptotheca acuminata isolated by Wall and Wani in 1966, inhibits DNA topoisomerase I; its approved derivatives are irinotecan and topotecan.

Campylobacter

Campylobacter is a genus of gram-negative bacteria that live in the intestines of birds and other warm-blooded animals and are among the leading bacterial causes of diarrhea in humans.

Campylobacter bacteriophage preparation

Campylobacter bacteriophage preparation: lytic phage cocktails (Intralytix GRN 966, three to eight C. jejuni phages, FDA GRAS 2021) applied to raw poultry and red meat at up to 10^8 PFU/g, reducing Campylobacter by 0.2 to over 5 log10 CFU depending on conditions.

Campylobacter coli

Campylobacter coli, formerly Vibrio coli (Doyle 1948), is a gram-negative foodborne bacterium of swine, poultry, and humans; the second most common Campylobacter causing human gastroenteritis, with higher antimicrobial resistance than C. jejuni.

Campylobacter fetus

Campylobacter fetus: type species of the Campylobacter genus, a microaerophilic gram-negative bacterium causing bovine venereal campylobacteriosis and opportunistic human bacteremia; subspecies fetus, venerealis, and testudinum; S-layer-mediated immune evasion.

Campylobacter jejuni

Campylobacter jejuni, a Gram-negative spiral foodborne bacterium, is the leading cause of bacterial gastroenteritis worldwide, transmitted mainly by poultry, and increasingly fluoroquinolone-resistant.

Campylobacteriosis

Gastroenteritis due to Campylobacter (campylobacteriosis), mainly C. jejuni, is the world's most common bacterial gastroenteritis: foodborne, usually from poultry, with bloody diarrhea, fever, and rare Guillain-Barré complications.

Camrelizumab

Camrelizumab (AiRuiKa, SHR-1210), Jiangsu Hengrui's humanized anti-PD-1 monoclonal antibody; first approved in China 2019 for relapsed/refractory classical Hodgkin lymphoma, later nine NMPA indications; not FDA approved.

Camurati-Engelmann disease

Camurati-Engelmann disease, also called progressive diaphyseal dysplasia, is a rare autosomal dominant bone disorder causing limb pain, waddling gait, and muscle weakness, usually caused by TGFB1 mutations.

Can f 1

Can f 1 (Canis familiaris allergen 1, e101) is a 22-25 kDa salivary lipocalin, a major dog dander allergen sensitizing 40-75% of dog-allergic patients, with an eight-stranded beta-barrel structure and likely cross-reactivity with cat Fel d 7.

CAN trial

CAN trial (Cancer and Anesthesia study, NCT01975064): Swedish-led pragmatic RCT comparing propofol-based with sevoflurane-based general anesthesia for radical breast and colorectal cancer surgery; breast cohort (1,670 analyzed) found no five-year survival difference.