edgepedia

Life and health

72,234 articles

Crotamiton

Crotamiton (Eurax, Crotan) is a topical 10% cream or lotion scabicidal and antipruritic drug for scabies and itching; mechanism unknown, less effective than permethrin, favored in infants for low toxicity.

Crotaphytus

Crotaphytus, the collared lizards (Holbrook, 1842), is a genus of nine species of large, fast, carnivorous iguanian lizards in Crotaphytidae, ranging from southern Idaho to Baja California and northern Mexico, distinct from the leopard lizard genus Gambelia.

Croton (plant)

Croton (plant): large Euphorbiaceae genus published by Linnaeus in 1753, about 1,100–1,300 species, mostly Neotropical; diterpenoid-rich, medicinal, and often confused with the ornamental Codiaeum variegatum.

Croton lechleri

Croton lechleri (sangre de grado, dragon's blood) is a South American Euphorbiaceae tree whose red latex yields crofelemer (Mytesi), an FDA-approved antidiarrheal for HIV/AIDS patients.

Croup

Croup (laryngotracheobronchitis) is a viral childhood illness of the larynx and trachea causing barking cough, hoarseness, and inspiratory stridor, mostly from parainfluenza virus, treated with dexamethasone and nebulized epinephrine.

Crouzon syndrome

Crouzon syndrome, also called craniofacial dysostosis, is an autosomal dominant craniosynostosis disorder caused mainly by FGFR2 gain-of-function mutations, with proptosis, midface hypoplasia, normal intelligence, and an FGFR3 acanthosis nigricans variant.

Crovalimab

Crovalimab (Piasky, SKY59, RO7112689) is a recycling anti-C5 monoclonal antibody approved in 2024 for paroxysmal nocturnal hemoglobinuria, given subcutaneously every 4 weeks after IV loading; non-inferior to eculizumab in COMMODORE 2.

Crow

Crow: any of about 46-50 species of genus Corvus, family Corvidae, black omnivorous songbirds found worldwide except Antarctica; known for winter roosts of up to two million birds, tool use, and primate-like cognition.

Crown lengthening

Crown lengthening is a periodontal surgical procedure exposing more tooth structure by repositioning gum tissue, used to restore damaged teeth or improve a gummy smile.

Crown rust

Crown rust, or oat crown rust, is a fungal disease of oats caused by Puccinia coronata f. sp. avenae, spread by buckthorn alternate hosts, causing 10-40% yield losses worldwide and distinguished from oat stem rust by small orange pustules.

Crown shyness

Crown shyness, also called canopy disengagement or inter-crown spacing, is the phenomenon where crowns of fully stocked trees avoid touching, leaving channel-like canopy gaps; wind-induced abrasion is the best-supported cause.

Crown-of-thorns starfish

Crown-of-thorns starfish (Acanthaster spp., COTS) are venomous-spined coral-eating starfish of the Indo-Pacific whose periodic outbreaks, roughly every 15 years on the Great Barrier Reef, are a leading cause of coral loss, managed by diver culling with vinegar or ox bile injections.

Crown-rump length

Crown-rump length (CRL) is the first-trimester ultrasound measure from fetal crown to rump, the standard pregnancy-dating method (±5–7 days to 13 6/7 weeks), introduced as a term by Mall in 1907 and first measured in vivo by Robinson in 1973.

Crowned Crane

Balearica is the crane genus (subfamily Balearicinae) containing Africa's two crowned cranes, Black Crowned Crane Balearica pavonina and Grey Crowned Crane Balearica regulorum; the oldest crane lineage, tree-roosting, with both species threatened.

Crowned eagle

Crowned eagle (Stephanoaetus coronatus), African crowned eagle or crowned hawk-eagle: a powerful crested forest raptor of sub-Saharan Africa, Africa's most powerful eagle by prey weight, killing animals up to 20 kg, and Near Threatened globally.

CRT (genetics)

crt genes (crtE, crtB, crtI, crtY, crtW, crtO) are bacterial carotenoid biosynthesis genes encoding GGPP synthase, phytoene synthase, phytoene desaturase, and tailoring enzymes, widely used in metabolic engineering of crops and microbes.

CRT_TriageER study

CRT_TriageER (NCT07054151) is a 2024 cross-sectional study by Sofuoglu and Başer, Izmir Democracy University, of capillary refill time in 313 emergency department patients, finding mean CRT 2.00 s, longer in red triage codes.

CRTC1

CRTC1 (MECT1, TORC1) is a human gene at 19p13.11 encoding a CREB-regulated transcription coactivator active in brain memory pathways and, as the CRTC1-MAML2 fusion from t(11;19), the major oncogenic driver of mucoepidermoid carcinoma.

CRTC2

CRTC2 (TORC2), CREB-regulated transcription coactivator 2 gene at 1q21.3; cAMP/calcium-activated CREB coactivator driving hepatic gluconeogenesis, GLP-1 production, and context-dependent tumor suppressor or oncogene roles.

Cruciate ligament

The cruciate ligaments, or ligamenta cruciata, are the two crossed ligaments inside the knee, the anterior and posterior cruciate, which control front-to-back and rotational stability.

Crucibulum

Crucibulum is a small genus of bird's nest fungi whose urn-shaped fruiting bodies contain whitish spore packets that raindrops splash out to adhere to nearby surfaces.

Cruciferous vegetables

Cruciferous vegetables, also called Brassica vegetables, include broccoli, cabbage, kale, cauliflower, Brussels sprouts, collard greens, and turnips; they contain glucosinolates converted by myrosinase into isothiocyanates such as sulforaphane.

Crumpet

The crumpet, or English crumpet, is a small, thick, round British griddle cake made from yeast-leavened batter, characterized by a holey top, and eaten toasted with butter.

Crunchwrap Supreme

Crunchwrap Supreme: Taco Bell's hexagonal folded-tortilla item with seasoned beef, nacho cheese, tostada shell, lettuce, tomato, and sour cream. Debuted June 2005, sold 51 million units in six weeks, permanent January 2006; invented by Lois Carson.

Crusekitug

Crusekitug (鲁塞奇塔单抗, QX002N) is Qyuns Therapeutics' humanized anti-IL-17A monoclonal antibody for ankylosing spondylitis; Phase III met endpoints (ASAS40 40.4% vs 18.9%) and its NMPA NDA was accepted March 9, 2026.

Crush syndrome

Crush syndrome, also called Bywaters' syndrome, is systemic illness from traumatic rhabdomyolysis after prolonged compression, causing acute kidney injury, hyperkalemia, and arrhythmias; it affects 2–15% of earthquake survivors and is distinct from local crush injury.

Crushed chest

Crushed chest (ICD-11 NB33.0) is a crushing injury of the thorax, typically causing multiple rib fractures, flail chest, and pulmonary contusion; managed with analgesia, physiotherapy, and selective ventilation.

Crushing injury of ankle

Crushing injury of ankle is damage to soft tissues around the ankle joint from direct compression by an external force like a falling object, machinery, or collapsing debris.

Crushing injury of elbow

Crushing injury of elbow (ICD-11 NC37.0; ICD-10-CM S57.0) is crush trauma to the elbow from squeezing force, causing fracture, nerve injury, compartment syndrome, and infection, managed with first aid, surgery, and rehabilitation.

Crushing injury of face

Crushing injury of face (ICD-11 NA08.1) is facial tissue damage from a crushing external force, a child of NA08 crushing injury of head. Priorities are airway, hemorrhage control, fracture repair, and reconstruction.