72,234 articles
Dermatophytosis of nail
Dermatophytosis of nail (tinea unguium, dermatophytic onychomycosis, ICD-11 1F28.1) is a dermatophyte fungal nail infection, mostly Trichophyton rubrum, causing 90% of toenail cases; treated with terbinafine or azoles.
Dermatopontin
Dermatopontin (DPT, TRAMP) is a 22-kDa non-collagenous extracellular matrix protein abundant in dermis that accelerates collagen and fibronectin fibril formation, enhances TGF-β activity, promotes cell adhesion and wound re-epithelialization, and is reduced in fibrotic and diabetic skin.
Dermatoses of infancy
Dermatoses of infancy (ICD-11 EH40) are skin diseases of infants from birth to about 2 years, including infantile seborrhoeic dermatitis, napkin dermatoses, erythrodermas, and acute haemorrhagic oedema of infancy.
Dermatosparaxis Ehlers-Danlos syndrome
Dermatosparaxis Ehlers-Danlos syndrome (dEDS, EDS type VIIC, OMIM 225410) is an ultra-rare autosomal recessive ADAMTS2-related EDS with extreme skin fragility, lax skin, bruising, and hieroglyphic collagen fibrils on electron microscopy.
Dermestidae
Dermestidae, the skin, hide, larder, and carpet beetles, is a beetle family whose larvae scavenge dried animal matter; the khapra beetle Trogoderma granarium is its worst stored-product pest.
Dermis
Dermis (corium): the middle, connective-tissue layer of skin between epidermis and hypodermis, with papillary and reticular layers, collagen, elastin, vessels, nerves, glands, and hair follicles.
Dermochondrocorneal dystrophy
Dermochondrocorneal dystrophy, or François syndrome (OMIM 221800), is an extremely rare childhood-onset disorder combining skin nodules, hand and foot osteochondrodystrophy, and corneal opacities; fewer than 20 patients reported, inheritance uncertain, no gene identified.
Dermographism
Dermographism is a skin condition in which firm stroking or scratching produces raised red lines within minutes, the most common form of chronic inducible urticaria, first treated with antihistamines.
Dermoid cyst
The dermoid cyst, also known as a mature teratoma or benign cystic teratoma, is a benign ovarian germ cell tumor that commonly contains tissue from all three germ layers.
Dermophiidae
Dermophiidae, the Neotropical and Tropical African caecilians, is a family of limbless amphibians with four genera (Dermophis, Geotrypetes, Gymnopis, Schistometopum) and 15 viviparous species ranging from Mexico to Colombia and West Africa to Kenya.
Dermophis donaldtrumpi
Dermophis donaldtrumpi is a proposed name for a newly discovered, nearly blind, 10 cm caecilian from Panama, named in December 2018 after Donald Trump by EnviroBuild, which paid $25,000 at a Rainforest Trust auction to protest his climate stance; the name awaits formal publication.
Dermoscopy
Dermoscopy, also called dermatoscopy or epiluminescence microscopy, is a noninvasive technique using a magnifying illuminated device to visualize subsurface skin structures and detect melanoma earlier.
Dermot M.F. Cooper
Dermot M.F. Cooper is a pharmacologist known for his work on adenylyl cyclases and calcium regulation of cyclic AMP, holding faculty positions at the University of Colorado and Cambridge.
Derrick J. Rossi
Derrick J. Rossi is a Canadian stem cell biologist and entrepreneur who developed modified mRNA for cellular reprogramming, co-founded Moderna Therapeutics, and leads Convelo Therapeutics.
Derrick T. Brazill
Derrick T. Brazill is an American cell biologist whose research on cell density sensing and the actin cytoskeleton earned a 2004 PECASE award; he is now Provost of York College, CUNY.
Dersimelagon
Dersimelagon (MT-7117) is an investigational oral selective MC1R agonist by Tanabe Pharma, now LEO Pharma, for EPP and XLP phototoxicity; positive phase 2 and INSPIRE phase 3 trials, FDA NDA under Priority Review.
DES
DES is a human gene on chromosome 2q35 that provides instructions for desmin, the intermediate filament protein of cardiac, skeletal, and smooth muscle; pathogenic variants cause desminopathy, often with cardiomyopathy.
Des R. Richardson
Des R. Richardson is an Australian pharmacologist and biochemist who directs the Centre for Cancer Cell Biology at Griffith University and developed the anticancer iron chelators Dp44mT and DpC.
Desbuquois syndrome
Desbuquois syndrome (DBQD, Desbuquois dysplasia) is a rare autosomal recessive osteochondrodysplasia with severe micromelic dwarfism, joint laxity with multiple dislocations, advanced carpotarsal ossification; caused by CANT1 (type 1, Kim variant) or XYLT1 (type 2) mutations.
Descemet membrane endothelial keratoplasty
Descemet membrane endothelial keratoplasty (DMEK) is a corneal transplant operation replacing the endothelium and Descemet membrane with a thin donor graft, used mainly for Fuchs dystrophy and bullous keratopathy.
Descemet stripping endothelial keratoplasty
Descemet stripping endothelial keratoplasty (DSEK) is a partial-thickness corneal transplant for endothelial disease such as Fuchs dystrophy, replacing the endothelium and Descemet membrane through a small, sutureless incision.
Deschampsia
Deschampsia (hair grass), Poaceae genus established by Palisot de Beauvois in 1812, type D. cespitosa; about 64 species native from subarctic to temperate zones, including Antarctic D. antarctica.
Described taxa of Thermococci and Archaeoglobi
A nomenclatural reference enumerating the validly published species and genera of the archaeal classes Thermococci and Archaeoglobi, with description years, corrections, and recent additions such as Thermococcus radiotolerans.
Desensitization (psychology)
Desensitization (systematic desensitization) is Joseph Wolpe's behavior therapy for phobias and anxiety, pairing graded exposure to a feared hierarchy with relaxation via reciprocal inhibition; now largely subsumed under exposure therapy.
Deserpidine
Deserpidine, a Rauwolfia alkaloid antihypertensive related to reserpine, ATC C02AA05/C02LA03, formula C32H38N2O8, first approved 1957; brands Harmonyl, Oreticyl, Enduronyl; depletes catecholamines.
Desert locust
Desert locust (Schistocerca gregaria), FAO's most destructive migratory pest; swarming grasshopper of Africa, Near East, and South-West Asia; swarms of 40-80 million per km2 eat their own weight daily and plagues can cover 29 million km2.
Desert rain frog
Desert rain frog (Breviceps macrops), also web-footed rain frog or Melkpadda, a small burrowing Brevicipitidae frog of fog-covered coastal dunes from Kleinsee, South Africa to Lüderitz, Namibia; IUCN Vulnerable since 2026, threatened by diamond strip mining and coastal development.
Desert tortoise
Desert tortoise (Gopherus agassizii, also G. morafkai and G. evgoodei), Agassiz's desert tortoise, a burrowing tortoise of the Mojave and Sonoran deserts; largest U.S. terrestrial turtle, ESA-threatened, IUCN Critically Endangered.
Desertum
Desertum is a genus of small alligator lizards (Anguidae, Gerrhonotinae) erected in 2022, containing Desertum lugoi and D. lazcanoi, endemic to rocky arid shrubland of Coahuila and Nuevo León, Mexico, above 730 m, distinguished by smooth dorsal scales.
Desflurane
Desflurane: highly fluorinated volatile inhalational anesthetic synthesized by Terrell (compound 653, 1959–1966), introduced 1992; low blood solubility, high vapor pressure needing heated vaporizers, airway irritant, and GWP100 of 2540, now being eliminated worldwide.