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Life and health

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Desh Pal S. Verma

Desh Pal S. Verma was a Canadian-American plant molecular biologist and Ohio State professor who isolated the first plant mRNA and identified nodulins, dying in 2025.

Deshayesites

Deshayesites is an extinct lower Aptian (Early Cretaceous) ammonite genus of the family Deshayesitidae, type species D. deshayesi (d'Orbigny, 1841); its first appearance marks the Aptian base in the Tethyan realm and its zones define lower Aptian biostratigraphy.

Desiccation tolerance in ferns

Desiccation tolerance in ferns is the ability of certain ferns and lycophytes to lose almost all cellular water, suspend metabolism, and resume normal function after rehydration.

Desiccation tolerance in land gastropods

Desiccation tolerance in land gastropods is the set of adaptations, including aestivation, epiphragms, and humidity-seeking behavior, that lets snails and slugs survive losing most of their body water.

Desidae

Desidae (Pocock, 1895) is a spider family of about 324 species in 63 genera, mostly Australian and New Zealand, including intertidal Desis, sheet-web Cambridgea, and house spider Badumna; it has both cribellate and ecribellate species.

Desiderosmia

Desiderosmia is the excessive craving to smell specific odours without wanting to ingest them, associated with iron deficiency anaemia; term coined by Hansen et al. 2017, distinct from pica, resolves with iron replacement.

Desidustat

Desidustat (Oxemia) is an oral HIF prolyl hydroxylase inhibitor for anemia in chronic kidney disease, developed by Zydus Lifesciences and first approved in India in 2022.

Design Interactive

Design Interactive is an Orlando, Florida human-systems engineering firm founded in 1998 by Kay M. Stanney, building AR/VR training systems for military, medical, and aerospace customers.

Designed protein 2D lattices

Designed protein 2D lattices are planar, periodically ordered arrays of protein building blocks assembled with a prescribed geometry, either through engineered protein-protein interfaces or DNA origami scaffolds.

Designed protein nanocages

Designed protein nanocages, also called nanohedra, are artificial proteins that self-assemble into hollow geometric shells, engineered computationally or from natural cages for vaccines and drug delivery.

Designer baby

Designer baby: a baby whose genes are selected or altered before birth, via IVF embryo testing (PGT-M, polygenic scores) or CRISPR editing; first PGT births 1990, He Jiankui's 2018 CCR5-edited twins, widely restricted by law.

Designer drug

A designer drug is a synthetic psychoactive substance made by slightly modifying a controlled drug so it mimics the original's effects while evading existing legal controls.

Desipramine

Desipramine, sold under the brand name Norpramin, is a tricyclic antidepressant of the dibenzazepine type and the active metabolite of imipramine, approved in the United States in 1964 for the treatment of depression.

DESIR study

DESIR (DEvenir des Spondylarthropathies Indifférenciées Récentes) is a French inception cohort of 708 patients with recent-onset axial spondyloarthritis, recruited 2007-2010, used to validate ASAS criteria and track 10-year outcomes.

Desirability of outcome ranking

Desirability of outcome ranking (DOOR) is a patient-centric clinical trial endpoint that ranks each patient's overall outcome, combining benefits and harms, and compares treatments by the probability of a more desirable outcome.

Désiré Collen

Désiré Collen (born 1943) is a Belgian physician-scientist who cloned tissue-type plasminogen activator and developed it into alteplase, a clot-dissolving drug used worldwide for heart attack and stroke.

Désirée van der Heijde

Désirée van der Heijde is a Dutch rheumatologist, professor at Leiden University Medical Center, who developed the Disease Activity Score and the modified Sharp–van der Heijde scoring method.

Desirudin

Desirudin (Revasc, Iprivask) is a recombinant 65-amino-acid hirudin analogue and direct thrombin inhibitor for DVT prophylaxis after hip or knee replacement; EU authorization withdrawn 2014.

Deslanoside

Deslanoside (deacetyllanatoside C, Cedilanid-D) is a Digitalis lanata cardiac glycoside for heart failure and supraventricular arrhythmias; Na-K-ATPase inhibitor, half-life 38-77 h, discontinued in the US but available in Brazil, China, and Japan.

Desmana

Desmana is a monotypic genus of semi-aquatic moles (Talpidae, tribe Desmanini) holding only the Russian desman, Desmana moschata (Vykhukhol'), a musk-glanded, web-footed insectivore of slow Russian waters, now IUCN Critically Endangered with 8,000-10,000 individuals left.

Desmedipham

Desmedipham (CAS 13684-56-5), a phenylcarbamate photosynthesis-inhibiting herbicide, demethylated analog of phenmedipham, used post-emergence in sugar beet; EU approval non-renewed 2019, still registered in the US.

Desmetramadol

Desmetramadol (O-desmethyltramadol, M1, O-DSMT) is tramadol's active mu-opioid metabolite, studied as an investigational analgesic (20 mg equals 50 mg tramadol) and temporarily DEA Schedule I in the US since August 2026.

Desmetryn

Desmetryn (desmetryne, G 34360, trade name Semeron) is a methylthio-s-triazine herbicide introduced by Ciba-Geigy in 1964 for Brassica vegetables; it inhibits photosystem II and is no longer approved in the EU or marketed in the US.

Desminopathy

Desminopathy (desmin-related myofibrillar myopathy, MFM1, OMIM 601419) is a rare genetic muscle disease caused by DES gene mutations, causing progressive distal-onset weakness, cardiomyopathy, and respiratory insufficiency.

Desmoceras

Desmoceras (Zittel, 1884) is a smooth-shelled Cretaceous ammonoid genus in the family Desmoceratidae, type species Ammonites latidorsatus; known from Albian-Turonian strata of Japan, Sakhalin, Madagascar, and South Africa.

Desmodium

Desmodium (ticktrefoil, tickclover) is a genus of ~178 accepted Fabaceae species with lomentaceous pods bearing hooked hairs, native to the New World, Tropical Africa, and the southern Arabian Peninsula, used as forage legumes and in push–pull pest control.

Desmodium styracifolium total flavonoids capsules

Desmodium styracifolium total flavonoids capsules (广金钱草总黄酮胶囊, Guang Jing) are a Chinese category 1.2 TCM drug approved in 2022 for ureteral stones with damp-heat pattern; phase 3 trial showed 44.6% vs 33.8% stone passage by day 28.

Desmodus

Desmodus is a monotypic genus of vampire bats (Phyllostomidae) whose sole living species, the common vampire bat Desmodus rotundus, feeds exclusively on blood, transmits rabies to livestock, and ranges from northern Mexico to central Chile and Argentina.

Desmoglein-2

Desmoglein-2 (DSG2) is a cardiac desmosomal cadherin at 18q12 whose variants cause arrhythmogenic cardiomyopathy, accounting for roughly 2.5–10% of cases, with founder variant p.Phe531Cys common in China.

Desmognathus

Desmognathus, known as the dusky salamanders, is a genus of 39 lungless salamander species in eastern North America, ranging from aquatic to fully terrestrial adults.