72,234 articles
Effects of pornography
Effects of pornography: research on links between sexually explicit material use and sexual function, satisfaction, mental health, and behavior; ICD-11 CSBD, no DSM-5 porn addiction, mostly small mixed associations.
Effects of strenuous physical exercise
Effects of strenuous physical exercise (ICD-11 NF06) classifies acute bodily reactions to high-intensity exertion: exertional heat stroke, post-exercise postural hypotension, post-exertional dehydration, and exercise muscle cramp, within chapter 22 external-cause effects.
Effects of thirst
Effects of thirst (ICD-11 NF07.1) classifies consequences of water deprivation and polydipsia; thirst begins at plasma osmolality about 285 mOsm/kg and fails as a guide in the elderly and athletes.
Effects of Varroa mites on honey-bee colonies
Varroa mites (Varroa destructor) kill honey-bee colonies mainly by vectoring viruses, above all deformed wing virus; untreated colonies die within one to four years, driving US winter losses averaging 28.7% since 2006.
Effects of vibration
Effects of vibration: health consequences of hand-arm and whole-body vibration exposure, causing hand-arm vibration syndrome, back pain, and vascular and neurological injury; also therapeutic WBV training.
EFFICACE study
EFFICACE (NCT05114434) is a single-center, 8-week, open-label University of Parma study testing extrafine beclometasone/formoterol/glycopyrronium 87/5/9 µg on cough peak flow in moderate-to-severe COPD, distinct from the TRILOGY, TRIDENT, and TRIFORCE trials.
Efficacy
Efficacy (pharmacology): a drug's capacity, once receptor-bound, to change target behavior and produce response; distinct from affinity and potency. Spans Ariëns' intrinsic activity, Furchgott's intrinsic efficacy, receptor reserve, inverse agonism, and biased agonism.
Effie W. Petersdorf
Effie W. Petersdorf is a transplant physician-scientist at the Fred Hutchinson Cancer Research Center in Seattle whose registry-scale HLA matching studies established the 8/8 match standard for unrelated donor transplantation.
Effusion of joint
Effusion of joint (hydrarthrosis, ICD-11 FA36) is increased intra-articular synovial fluid from trauma, degeneration, inflammation, or infection. Diagnosed by ultrasound (~90% sensitive) and arthrocentesis; fluid leukocyte counts classify it, and septic arthritis must be excluded.
Efgartigimod alfa
Efgartigimod alfa, sold by argenx as VYVGART, is a neonatal Fc receptor blocker that lowers circulating IgG; the FDA approved it in 2021 for generalized myasthenia gravis.
EFIGRO trial
EFIGRO (NCT02258126) was a two-arm Spanish trial in Vitoria-Gasteiz testing supervised exercise added to a family-based lifestyle program in 116 children aged 8-12 with overweight/obesity; exercise raised hepatic-fat responder rates and IMAAT reduction mediated liver-fat improvement.
Efinaconazole
Efinaconazole (Jublia, Clenafin) is a 10% topical triazole antifungal solution for toenail onychomycosis, applied once daily for 48 weeks; approved in Canada 2013 and the US June 2014, superior to placebo but less effective than oral terbinafine.
Eflapegrastim
Eflapegrastim (Rolvedon, also known as Rolontis) is a long-acting recombinant human G-CSF that the FDA approved in September 2022 to reduce febrile neutropenia in adults receiving chemotherapy.
Eflornithine (α-difluoromethylornithine)
Eflornithine (α-difluoromethylornithine, DFMO) is an irreversible ornithine decarboxylase inhibitor used with nifurtimox (NECT) as first-line treatment for second-stage gambiense sleeping sickness, and as Vaniqa cream for hirsutism.
Efmoroctocog alfa
Efmoroctocog alfa (Elocta, Eloctate, BIIB031) is an extended half-life recombinant factor VIII-Fc fusion protein for treating and preventing bleeding in haemophilia A, given intravenously once or twice weekly.
EFNB2
EFNB2 (ephrin-B2) is a human 13q33.3 gene encoding a transmembrane ephrin-B ligand for Eph receptors, notably EphB4, essential for cardiovascular development and the entry receptor for Nipah and Hendra viruses.
Efpeglenatide
Efpeglenatide (에페글레나타이드, HM11260C) is Hanmi's once-weekly GLP-1 receptor agonist, an exendin-4-IgG4 Fc fusion. AMPLITUDE-O cut MACE 27% in type 2 diabetes; approved in Korea 2026 for obesity.
Efraim Racker
Efraim Racker (1913–1991) was an Austrian-born American biochemist at Cornell who resolved and reconstituted the enzymes of oxidative phosphorylation, discovered F1 ATPase, and helped demonstrate chemiosmotic coupling.
EFSATAEMD trial
EFSATAEMD (NCT07372001) is a completed Phase 4 Mexican pilot trial of topical lyophilized exosomes with microneedling for facial skin aging: 30 adults over 50, three sessions four weeks apart, favorable before-and-after results.
Efsubaglutide alfa injection
Efsubaglutide alfa (依苏帕格鲁肽α, Yi Nuo Qing) is Innogen Pharmaceuticals' human GLP-1/IgG2 Fc fusion GLP-1RA with a 204-hour half-life, approved in China in January 2025 for adult type 2 diabetes.
Eftrenonacog alfa
Eftrenonacog alfa (rFIXFc, Alprolix) is an extended half-life recombinant factor IX Fc fusion protein for haemophilia B; Fc-FcRn recycling gives an about 82-hour half-life, first FDA-approved March 2014, EU 2016, marketed by Sobi.
Efungumab
Efungumab (Mycograb, MYC-123), NeuTec Pharma's human recombinant anti-Hsp90 antibody fragment for invasive candidiasis; phase III positive but EMA refused marketing authorisation in 2007 and development was terminated.
Egas Moniz
Egas Moniz (1874–1955) was a Portuguese neurologist and statesman who invented cerebral angiography in 1927 and devised prefrontal leucotomy in 1935, winning the 1949 Nobel Prize in Medicine.
Ege T. Kavalali
Ege T. Kavalali, also known as Ege Kavalali, is a Turkish-born neuroscientist and Chair of Pharmacology at Vanderbilt University, known for establishing spontaneous neurotransmission as a distinct signaling pathway.
Egeria densa
Egeria densa (Brazilian waterweed, anacharis, Elodea densa), Hydrocharitaceae submerged aquatic plant native to South America, aquarium escape, male-only invasive populations, whorls of 4–8 serrated leaves, clogs waterways.
EGF-like domain
EGF-like domain: a 30–50 amino acid extracellular protein module with six conserved cysteines in three disulfide bonds (1–3, 2–4, 5–6), found in growth factors, Notch, coagulation factors, and fibrillin; calcium-binding cbEGF subtype; Pfam PF00008, InterPro IPR000742.
EGFL7
EGFL7 (VE-statin), a secreted 278-amino-acid endothelial protein with two EGF-like domains, regulates vascular tubulogenesis and Notch signaling; its gene hosts miR-126 and it is a biomarker in cancer, stroke, MS, and preeclampsia.
EGFR-AS1
EGFR-AS1 (EGFR antisense RNA 1) is a human long non-coding RNA transcribed opposite the EGFR gene that raises EGFR output and drives tumor proliferation, invasion, and treatment resistance.
EGFR-TKI therapy
EGFR-TKI therapy is drug treatment with tyrosine kinase inhibitors that block the epidermal growth factor receptor, used mainly for EGFR-mutated non-small-cell lung cancer, especially in Asian patients.
Egg
Egg: the female reproductive cell (ovum) of animals, also the shelled reproductive body of birds and reptiles. Amniotic egg, with four extraembryonic membranes, evolved 300-360 million years ago, enabling land reproduction.