edgepedia

Life and health

72,234 articles

Fluoxapiprolin

Fluoxapiprolin (CAS 1360819-11-9), a Bayer piperidinyl thiazole isoxazoline OSBPI fungicide (FRAC 49) for oomycete diseases such as late blight and downy mildew; sold as Xivana; not EU-approved, registered in Canada, US, New Zealand.

Fluoxastrobin

Fluoxastrobin (HEC 5725; trade names Evito, Disarm) is a strobilurin QoI fungicide, CAS 361377-29-9, first registered in the US in 2005 by Bayer CropScience, controlling blights, leaf spots, and rusts on vegetables, peanuts, and turf.

Fluoxetine

Fluoxetine (Prozac) is the first marketed SSRI antidepressant, developed by Eli Lilly (Fuller, Wong, Molloy), FDA-approved December 1987 for depression, OCD, bulimia, and panic disorder, patent expired 2001.

Fluoxymesterone

Fluoxymesterone (Halotestin, FXM) is a synthetic 17-alpha-alkylated androgenic anabolic steroid, first FDA-approved in 1956 and now discontinued, used orally for male hypogonadism, delayed puberty, and palliative treatment of inoperable metastatic breast cancer.

Flupentixol

Flupentixol (flupenthixol), thioxanthene first-generation antipsychotic, ATC N05AF01, brands Depixol, Psytixol, Fluanxol; oral and decanoate depot forms for schizophrenia; D1/D2 blockade; 2-4 week depot action.

Fluphenazine

Fluphenazine is a high-potency typical antipsychotic of the phenothiazine class, used for psychosis in schizophrenia and available as oral tablets or a long-acting decanoate injection.

Flupirtine

Flupirtine, a triaminopyridine non-opioid analgesic and selective neuronal potassium channel opener (Kv7/GIRK activator), was used in Europe from 1984 for pain with muscle tension until EMA withdrew it in 2018 over liver injury.

Flupoxam

Flupoxam (MON 18500, KNW-739) is a triazole carboxamide cellulose-biosynthesis-inhibitor herbicide introduced in 1989 for broadleaf weed control in winter cereals; targeting CESA1/CESA3, it is no longer EU-approved.

Fluprednisolone

Fluprednisolone (6α-fluoroprednisolone, Alphadrol) is a synthetic fluorinated glucocorticoid, C21H27FO5, about 2.5 times as potent as prednisolone; FDA-approved 1982, now discontinued.

Flupyrsulfuron methyl

Flupyrsulfuron-methyl, typically applied as its sodium salt flupyrsulfuron-methyl-sodium, is a DuPont sulfonylurea herbicide for grass and broadleaf weeds in cereals, inhibiting acetolactate synthase at rates near 12 grams per hectare.

Fluquinconazole

Fluquinconazole, a triazole (conazole) fungicide introduced by Schering in 1992, used mainly as a cereal take-all and canola blackleg seed treatment; EU-approved 2012-2021, later withdrawn in Great Britain.

Flurandrenolide

Flurandrenolide (fludroxycortide, brand Cordran) is a synthetic fluorinated topical corticosteroid for corticosteroid-responsive dermatoses, available as 0.05% cream, ointment, lotion, and 4 mcg/cm2 tape; FDA-approved 1965.

Flurazepam

Flurazepam is a long-acting benzodiazepine used mainly as a hypnotic for insomnia. Introduced in the United States in 1970 under the brand name Dalmane, it rapidly supplanted barbiturates for treating insomnia.

Flurbiprofen

Flurbiprofen is a chiral nonsteroidal anti-inflammatory drug sold as a racemic mixture, used for arthritis and pain, as eye drops preventing miosis, and in lozenges for sore throat.

Fluridone

Fluridone (CAS 59756-60-4) is a Group 12 systemic herbicide inhibiting phytoene desaturase, used mainly at 2-5 ppb in water against hydrilla and Eurasian watermilfoil; EPA-registered for aquatic use since 1986.

Flurochloridone

Flurochloridone (FLC), a chiral pyrrolidone pre-emergence herbicide (trans:cis 3:1) for potato, sunflower, cotton, and cereals; EU 2026 EFSA review found Repr. 1B toxicity, endocrine-disruptor criteria met, and TFA data gaps.

Fluroxypyr

Fluroxypyr (CAS 69377-81-7), a synthetic auxin pyridyloxy-carboxylate herbicide introduced in 1985, controls broadleaf weeds in cereals, pasture, turf, and rights of way; rapidly biodegraded in soil, low animal toxicity.

Flurpiridaz

Flurpiridaz (Flyrcado, flurpiridaz F 18, BMS-747158) is an FDA-approved (September 27, 2024) fluorine-18 PET myocardial perfusion radiotracer binding mitochondrial complex I, with 109-minute half-life and 94% extraction fraction, used to detect coronary artery disease.

Flurprimidol

Flurprimidol (Cutless, Topflor) is a pyrimidinyl plant growth regulator, CAS 56425-91-3, that inhibits gibberellin biosynthesis to retard growth of turf, ornamental trees, and bulb crops; registered in the US in 1989 but banned for pesticide use in the EU since 2009.

Flurtamone

Flurtamone (CAS 96525-23-4) is a racemic furanone bleaching herbicide inhibiting phytoene desaturase, used in cereals at 250-375 g ai/ha; EU approval expired 27 December 2018 over TFA groundwater and aquatic risk concerns.

Flushing (physiology)

Flushing, also called skin flushing or facial flushing, is a transient reddening of the skin, usually the face and neck, caused by increased blood flow and a feeling of warmth.

Flushing disorders

Flushing disorders: conditions of episodic skin reddening with warmth (hot flushes), classified in ICD-11 as EG02. Wet flushing suggests autonomic causes; dry flushing suggests drugs, carcinoid syndrome, or mast cell disease.

Flusilazole

Flusilazole, a silicon-containing triazole (conazole) fungicide, CAS 85509-19-9, C16H15F2N3Si, used on fruit, vegetables, and cereals; WHO class II, not EU-approved, index compound for acute triazole dietary risk.

Fluspirilene

Fluspirilene, marketed as Imap and Redeptin, is a long-acting injectable antipsychotic of the diphenylbutylpiperidine class used to treat chronic schizophrenia, given weekly by intramuscular injection.

Flusulfamide

Flusulfamide (Nebijin, MTF 651; CAS 106917-52-6) is a sulfonanilide soil fungicide developed by Mitsui Toatsu, used mainly against clubroot (Plasmodiophora brassicae) by inhibiting resting spore germination; not EU-approved, registered in Japan.

Flutafuranol

Flutafuranol, also called 18F-AZD4694 or 18F-NAV4694, is a fluorine-18 benzofuran PET radiotracer for brain beta-amyloid plaques, developed by AstraZeneca, with Kd 2.3 nM, low white matter binding, and near-identical imaging to 11C-PiB; used in research, not approved.

Flutamide

Flutamide (Eulexin) is a first-generation nonsteroidal antiandrogen, FDA approved in 1989 for prostate cancer. It competitively blocks the androgen receptor via its active metabolite 2-hydroxyflutamide, is used at 750 mg/day in combined androgen blockade, and carries a boxed warning for fatal hepatotoxicity.

Flutemetamol

Flutemetamol, sold as Vizamyl, is a radioactive diagnostic agent injected intravenously for brain PET imaging that estimates amyloid beta plaque density in adults with cognitive impairment.

Fluticasone furoate

Fluticasone furoate (FF) is a synthetic trifluorinated corticosteroid, a stable ester of fluticasone propionate, used once daily for asthma (Arnuity, Breo/Relvar Ellipta) and allergic rhinitis (Avamys), with very low systemic bioavailability.

Fluticasone propionate

Fluticasone propionate (FP, Flovent, Flonase, Cutivate, Xhance) is a trifluorinated androstane corticosteroid with 0.5 nmol/L glucocorticoid receptor affinity, used for asthma, rhinitis, sinusitis, and dermatoses; first US approval 1990, first Flovent generic 2026.