72,234 articles
Fuselloviridae
Fuselloviridae (SSVs, spindle-shaped archaeal viruses): temperate circular dsDNA viruses, 14.8-17.8 kbp, lemon-shaped virions with terminal fibres, infecting hyperthermophilic Sulfolobales archaea above 70 degrees C and below pH 4; type virus SSV1 from Beppu, Japan.
Fusidic acid
Fusidic acid (Fucidin) is a steroid-structured antibiotic produced by a fungus, discovered in 1960 at LEO Pharma in Denmark and used chiefly against staphylococcal skin infections.
Fusiform gyrus
Fusiform gyrus (gyrus fusiformis): spindle-shaped cortex on the underside of the temporal and occipital lobes, divided by the mid-fusiform sulcus; contains the fusiform face area and visual word form area, and is linked to prosopagnosia and dyslexia.
Fusion imaging
Fusion imaging is a medical imaging technique that overlays real-time ultrasound with previously acquired CT, MRI, or PET/CT, guiding biopsies and tumor ablations without radiation.
Fusion of labia
Fusion of labia, also known as labial fusion or labial adhesion, is a condition where the labia minora stick together, mainly affecting prepubertal girls with low estrogen.
Fusion prostate biopsy
Fusion prostate biopsy is a targeted technique that registers pre-procedure prostate MRI with real-time ultrasound so urologists can aim needles at MRI-visible suspicious lesions, one of three common MRI-targeted biopsy techniques.
Fusobacteria
Fusobacteria (phylum Fusobacteriota): anaerobic Gram-negative bacteria of the oropharynx, containing Fusobacterium; commensal bridging organism in oral biofilms and pathobiont linked to periodontitis and colorectal cancer.
Fusobacterium
Fusobacterium is a genus of gram-negative, anaerobic, rod-shaped bacteria found in humans and animals, including F. necrophorum, which causes Lemierre's syndrome, and F. nucleatum, linked to colorectal cancer.
Fusobacterium necrophorum
Fusobacterium necrophorum, also called necrobacillosis agent, is a gram-negative obligate anaerobe causing cattle liver abscesses and foot rot and, in humans, Lemierre's syndrome; two subspecies, leukotoxin as major virulence factor.
Fusobacterium nucleatum
Fusobacterium nucleatum, an anaerobic Gram-negative fusiform oral bacterium, dental-plaque bridging organism, opportunistic pathogen, and colorectal cancer-associated oncobacterium with adhesins FadA and Fap2.
Futibatinib
Futibatinib (Lytgobi, TAS-120) is an oral, irreversible covalent FGFR1–4 inhibitor approved in 2022 for previously treated FGFR2-rearranged intrahepatic cholangiocarcinoma; FOENIX-CCA2 showed 42% response rate.
FUTURE II trial
FUTURE II (NCT00092534, V501-015) is Merck's phase 3 trial of the quadrivalent HPV-6/11/16/18 vaccine in 12,167 women aged 15–26; 98% per-protocol efficacy against HPV16/18-related CIN2/3 or AIS, 100% effectiveness over 14 years. A separate coronary scaffold trial shares the name.
FutureFeed
FutureFeed is an Australian company founded by CSIRO in 2020 that licenses Asparagopsis seaweed feed, cutting cattle methane by 80%+ via bromoform; investors include Woolworths and GrainCorp.
Futuximab
Futuximab (mAb992), with modotuximab (mAb1024), forms Sym004, a 1:1 mixture of chimeric IgG1 anti-EGFR antibodies binding non-overlapping EGFR domain III epitopes, inducing EGFR internalization and degradation; investigated in colorectal, head and neck, esophageal cancers and glioblastoma.
Fuyuki Ishikawa
Fuyuki Ishikawa is a Japanese physician-scientist with an M.D. and Ph.D. from the University of Tokyo, known for identifying the mammalian telomerase protein component TLP1 in 1997 and for telomere research in fission yeast.
Fuzi Decoction
附子汤 (Fuzi Decoction), a classical formula from Zhang Zhongjing's Shanghan Lun: processed aconite, poria, ginseng, atractylodes, and peony, warming yang and dispelling cold-damp for shaoyin disease with back aversion to cold and joint pain; distinct from Zhenwu Decoction by one herb.
FV Northwestern
The FV Northwestern is an American crab fishing vessel built in Seattle in 1977 and operated by the Hansen family in Alaska's Bering Sea crab fisheries.
FVB/N
FVB/N (Friend Virus B NIH) is an inbred albino laboratory mouse strain from NIH, homozygous for Fv1b and Pde6b rd1 retinal degeneration, favored for transgenic production due to large pronuclei and large litters.
FVB/NJ
FVB/NJ (Friend Virus B NIH Jackson) is an albino inbred laboratory mouse strain from NIH Swiss stock, used for transgenic production via large pronuclei, carrying rd1 blindness and C5 deficiency, with a published 50-fold genome sequence.
Fyodor Kondrashov
Fyodor A. Kondrashov (Фёдор Кондрашов, born 1979) is an evolutionary and synthetic biologist, professor at the Okinawa Institute of Science and Technology, known for work on fitness landscapes and epistasis.
FZD4
FZD4 (frizzled class receptor 4, also Fz4, EVR1, CD344) is a human gene at 11q14.2 encoding a 537-amino-acid seven-transmembrane Wnt receptor that binds norrin; loss-of-function variants cause autosomal dominant familial exudative vitreoretinopathy.
G matrix (quantitative genetics)
The G matrix is the additive genetic variance–covariance matrix of quantitative traits in a population, which paired with selection gradients predicts the rate and direction of evolution.
G protein
G proteins are guanine nucleotide-binding molecular switches, active with GTP and inactive with GDP, relaying signals from GPCRs; heterotrimeric forms have 16 α, 5 β, 14 γ human genes, and their discovery won Gilman and Rodbell the 1994 Nobel Prize.
G protein pathway suppressor 2
GPS2 (G protein pathway suppressor 2), also AMF-1, a 327-aa human corepressor protein in the NCoR/SMRT/HDAC3 complex at 17p13.1, with anti-inflammatory JNK-inhibiting and metabolic roles.
G protein-coupled receptor
G protein-coupled receptor (GPCR), also called seven-transmembrane receptor: largest human membrane protein family, over 800 members, signaling via heterotrimeric G proteins, GRK/arrestin regulation, and roughly 30-34% of FDA-approved drugs.
G protein-coupled receptor 3
GPR3 (G protein-coupled receptor 3, ACCA) is a human orphan class A GPCR, cloned in 1995, that constitutively activates Gs/adenylyl cyclase and cAMP signaling; it is linked to Alzheimer's amyloid-beta production, oocyte meiotic arrest, and neuropathic pain, with no validated endogenous ligand.
G-292 clone A141B1
G-292 clone A141B1 (CVCL_2909, ATCC CRL-1423) is a human osteosarcoma cell line from the bone of a 9-year-old White female, fibroblast-like, with a DAXX-KIFC3 fusion, used in bone cancer and drug screening research.
G-361
G-361 (G361; CVCL_1220; ATCC CRL-1424) is a human malignant melanoma cell line from a 31-year-old male's skin, BRAF V600E-mutant, p53 wild-type, used in toxicology, drug-response, and 3D skin model research.
G-401
G-401 (G401, CVCL_0270, ATCC CRL-1441) is a human kidney cancer cell line established in 1975 from a 3-month-old male, long misclassified as Wilms tumor but reclassified in 1993 as rhabdoid tumor of the kidney with homozygous SMARCB1 deletion.
G-402
G-402 (G402, ATCC CRL-1440, Cellosaurus CVCL_1221) is a human epithelial-like kidney cancer cell line from a 9-month-old female, deposited by PT Peebles; hyperdiploid (modal 47), McCoy's 5a culture, used in renal cancer and DepMap research.