72,234 articles
GSR-ET study
The GSR-ET study (German Stroke Registry–Endovascular Treatment) is an academic, industry-independent registry evaluating endovascular treatment of acute ischemic stroke in routine care at 25 German stroke centers since 2015.
GSS trial
The GSS trial, or Good Schools Study, was a cluster randomized trial in 42 Ugandan primary schools that found the Good School Toolkit cut staff violence by 42%.
GSTA1
GSTA1 (glutathione S-transferase alpha 1, GST2, GSTA1-1) is a human gene on 6p12.2 encoding a liver-abundant alpha-class glutathione transferase homodimer that detoxifies electrophiles and drugs; the GSTA1*B promoter variant reduces hepatic expression and busulfan clearance.
GSTM1
GSTM1 (glutathione S-transferase mu 1, HGNC:4632, NCBI 2944) is a human mu-class GST gene at 1p13.3 detoxifying electrophiles via glutathione conjugation; its common GSTM1*0 whole-gene deletion null allele, present in about half of people, modestly raises lung and head-and-neck cancer risk.
GSTM3
GSTM3 (glutathione S-transferase mu 3, GST5, GSTB) is a human gene at 1p13.3 in the mu-class GST cluster encoding a 225-aa homodimeric glutathione transferase (EC 2.5.1.18), highly expressed in testis and kidney, polymorphic at an intron 6 indel studied for cancer risk.
GSTO1
GSTO1 (glutathione S-transferase omega 1, GSTO 1-1, p28) is a human cytosolic omega-class GST on chromosome 10q24.3 with a catalytic Cys32 that catalyzes deglutathionylation, dehydroascorbate reduction, and monomethylarsonate reduction, and is an inflammation and cancer drug target.
GSTP1
Glutathione S-transferase, Pi class (GSTP1-1, EC 2.5.1.18), human pi-class detoxification enzyme on chromosome 11q13; homodimer conjugating GSH with electrophiles, inhibits JNK, overexpressed in tumors, Ile105Val polymorphism, promoter methylation cancer biomarker.
GSTT1
GSTT1 (glutathione S-transferase theta 1) is a human detoxification gene at 22q11.23 whose enzyme conjugates glutathione to electrophilic compounds; the gene is deleted (null) in 38% of people.
GTF2I
GTF2I, also known as TFII-I, is a human gene on chromosome 7 encoding a transcription factor; its deletion contributes to the social behavior traits of Williams-Beuren syndrome.
GTP-binding nuclear protein Ran-related
GTP-binding nuclear protein Ran-related: Ran (Ras-related nuclear protein), a small Ras-superfamily GTPase and its related genes, controlling nucleocytoplasmic transport directionality via the RanGTP gradient and mitotic spindle assembly.
GTPase-activating protein
GTPase-activating protein (GAP): a regulatory protein that accelerates GTP hydrolysis by GTP-binding proteins, switching them off. Includes RasGAP/RASA1, neurofibromin, RhoGAPs, TBC Rab GAPs, arginine finger mechanism, and cancer links.
Gua sha (刮痧)
Gua sha (刮痧), also called coining, cao gio, or kerokan, is a traditional East Asian therapy that press-strokes lubricated skin with a smooth-edged tool to raise petechiae lasting 2-5 days; trial evidence for pain relief remains low-certainty.
Guadalupe García–Tsao
Guadalupe Garcia-Tsao, born in Mexico City, is a hepatologist, Professor of Medicine at Yale, and Chief of Digestive Diseases at VA Connecticut, known for portal hypertension and cirrhosis research.
Guadecitabine
Guadecitabine (SGI-110, S110) is an investigational dinucleotide prodrug of decitabine, resistant to cytidine deaminase, that inhibits DNMT1; its phase 3 ASTRAL-1 AML trial missed its primary endpoint.
Guadua
Guadua is a genus of thorny, clumping, woody bamboo native from Mexico to southern tropical America and Trinidad, best known through Guadua angustifolia, the timber bamboo used in regulated construction in Colombia and Ecuador.
Guadua angustifolia
Guadua angustifolia, known as Colombian timber bamboo or simply guadua, is a large thorny bamboo native to South America and its most important timber bamboo.
Guaiac-based fecal occult blood test
The guaiac-based fecal occult blood test (gFOBT) is a chemical stool test that detects heme from bleeding anywhere in the gastrointestinal tract, used for colorectal cancer screening.
Guaifenesin
Guaifenesin (glyceryl guaiacolate ether), an oral expectorant derived from guaiac resin, thins airway mucus; the only OTC expectorant marketed in the US, sold as Mucinex and Robitussin since the 1989 monograph.
Guajillo chili
Guajillo chili, the dried mirasol pepper (Capsicum annuum), is Mexico's second most used dried chile after the ancho: tangy, fruity, bright red, 2,500–5,000 SHU, used in salsas, adobos, birria, and tamales.
Gualou Guizhi Tang
瓜蒌桂枝汤 (Gualou Guizhi Tang, 栝蒌桂枝汤), a Han-dynasty decoction from the Jingui Yaolüe: Guizhi Tang plus trichosanthes root (tianhuafen), the classic formula for taiyang soft tetany with body stiffness, sweating, and a deep slow pulse; listed in China's second batch of ancient classic famous formulas.
Guanabenz
Guanabenz (Wytensin) is a centrally acting alpha-2 adrenergic agonist antihypertensive, dosed 8–32 mg/day twice daily; discontinued in the US and investigated for ALS and vanishing white matter.
Guanaco
The guanaco (Lama guanicoe, also called huanaco) is a wild camelid native to South America, ranging from Peru to Tierra del Fuego and ancestral to the domestic llama.
Guanadrel
Guanadrel (Hylorel) is a discontinued oral postganglionic sympathetic inhibitor, a guanidine analog of guanethidine, FDA-approved in 1982 for mild to moderate hypertension.
Guanfacine
Guanfacine (Tenex IR, Intuniv ER) is a selective alpha-2A-adrenergic receptor agonist; a nonstimulant second-line ADHD medication for children and adolescents, also used adjunctively with stimulants and for tics, with somnolence and hypotension as key effects.
Guanfu base A hydrochloride
Guanfu base A hydrochloride (盐酸关附甲素, acehytisine hydrochloride) is a diterpene alkaloid antiarrhythmic from Aconitum coreanum roots; a multi-ion channel blocker with atrial-selective sodium channel inhibition used for supraventricular tachycardia in China.
Guang‐Zhong Yang
Guang-Zhong Yang (杨广中) is a medical robotics researcher and founding dean of the Institute of Medical Robotics at Shanghai Jiao Tong University, and founding editor of Science Robotics.
Guanidinoacetate methyltransferase deficiency
Guanidinoacetate methyltransferase (GAMT) deficiency is an inherited metabolic disorder in which the body cannot make creatine and guanidinoacetate accumulates, causing epilepsy, intellectual disability, and treatable neurological disease.
Guanidinoacetate N-methyltransferase
Guanidinoacetate N-methyltransferase (GAMT, EC 2.1.1.2, gene at 19p13.3) is the enzyme that methylates guanidinoacetate with SAM to complete creatine synthesis; its deficiency causes a treatable epilepsy-intellectual disability disorder.
Guanine
Guanine (G), C5H5N5O, is the purine DNA/RNA base pairing with cytosine via three hydrogen bonds; recycled by HGPRT to GMP, forms G-quadruplexes, prone to 8-oxo oxidation, and detected in the Ryugu asteroid.
Guanine deaminase
Guanine deaminase (GDA, guanase, cypin), EC 3.5.4.3, is a zinc-dependent enzyme converting guanine to xanthine and ammonia in purine catabolism; human AHS-fold and bacterial CDA-fold forms exist, and serum activity marks liver disease.