400 articles
NCI-H1155
NCI-H1155 (H1155) is a human lung large cell carcinoma cell line from a lymph node metastasis in a 36-year-old man, KRAS Q61H and TP53 R273H mutant, suspension-growing; ATCC CRL-5818, Cellosaurus CVCL_1456.
NCI-H125
NCI-H125 (H125, HUT-125, CVCL_3968, ATCC CRL-5801) is a human lung adenosquamous carcinoma cell line from a 61-year-old male donor, metastatic hypodermis origin, TP53-mutant, with discontinued ATCC and KCLB distribution.
NCI-H1341
NCI-H1341 (CVCL_1463, ATCC CRL-5864) is a human cancer cell line established in 1986, long distributed as small cell lung cancer but reclassified as HPV16-positive small cell carcinoma of the cervix, TP53/RB1 wild type with PIK3CA E524K and PTEN deletion.
NCI-H1385
NCI-H1385 (H1385, CVCL_1466) is a human lung squamous cell carcinoma cell line established in 1986 from a lymph node metastasis in a 49-year-old Black female smoker, carrying heterozygous KRAS G12C, distributed as ATCC CRL-5867.
NCI-H1436
NCI-H1436 (H1436, CVCL_1471, ATCC CRL-5871) is a human small cell lung cancer cell line from a 39-year-old male smoker's lymph node metastasis, established in 1986 by Gazdar and Minna, TP53-mutant and microsatellite stable.
NCI-H1437
NCI-H1437 (H1437, CVCL_1472) is a human lung adenocarcinoma cell line established in 1986 from a pleural effusion; carries MAP2K1 Q56P and TP53 R267P mutations and is trametinib-sensitive.
NCI-H146
NCI-H146 (also H146) is a human small cell lung cancer cell line established in 1979 by Adi F. Gazdar from a bone marrow metastasis, taken before therapy.
NCI-H1568
NCI-H1568 (H1568; CVCL_1476; ATCC CRL-5876) is a human lung adenocarcinoma cell line established in 1986 from a lymph node metastasis in a 48-year-old female smoker, with TP53 and ATM mutations and wild-type EGFR and KRAS.
NCI-H157
NCI-H157 (H157, CVCL_0463) is a human lung squamous cell carcinoma cell line from a 59-year-old male, with KRAS G12R and SMARCA4 mutations; it is a registered contaminated line identical to NCI-H1264, distinct from NCI-H1573.
NCI-H1581
NCI-H1581 (H1581), ATCC CRL-5878, Cellosaurus CVCL_1479: a human lung large cell carcinoma cell line from a 44-year-old male smoker, established 1987, FGFR1-amplified and FGFR inhibitor-sensitive, used in cancer research and DepMap.
NCI-H1607
NCI-H1607 (H1607, CVCL_A467) is a human small cell lung cancer cell line from a metastatic lymph node of a 54-year-old male smoker, carrying a TP53 p.Pro151His mutation, paired with the EBV-transformed line NCI-BL1607.
NCI-H1650
NCI-H1650, also written H1650, is a human lung adenocarcinoma cell line established in 1987 from a 27-year-old male smoker, used as a model of EGFR inhibitor resistance.
NCI-H1666
NCI-H1666 (H1666, CVCL_1485) is a human lung adenocarcinoma (bronchoalveolar) cell line from a 50-year-old female's pleural effusion, established 1987, BRAF G466V mutant, TP53 mutant, ATCC CRL-5885.
NCI-H1755
NCI-H1755 (H1755, CVCL_1492, ATCC CRL-5892) is a human lung adenocarcinoma cell line established in 1987 from a 65-year-old female smoker, carrying BRAF G469A and TP53 C242F mutations, ASCL1-positive, used in cancer and drug research.
NCI-H1792
NCI-H1792 (H1792, CVCL_1495, ATCC CRL-5895) is a human lung adenocarcinoma cell line from a 50-year-old male's pleural effusion, carrying KRAS G12C, homozygous TP53 splice-donor, and CDKN2A mutations, used in NSCLC and KRAS inhibitor research.
NCI-H1819
NCI-H1819 (H1819, CVCL_1497, ATCC CRL-5897) is a human lung adenocarcinoma cell line established in 1988 from a lymph node metastasis in a 55-year-old female smoker; SMARCA4-null, TP53-mutant, used in DepMap and CellMinerCDB.
NCI-H1836
NCI-H1836 (H1836, CVCL_1498, ATCC CRL-5898) is a human small cell lung cancer cell line established in 1988 from a 52-year-old male smoker, with TP53 and ALK mutations, STR-profiled and used in DepMap and GDSC screens.
NCI-H1838
NCI-H1838 (H1838, CVCL_1499, ATCC CRL-5899) is a human lung adenocarcinoma cell line established in 1988 from a female non-smoker, EGFR-amplified, KRAS wild-type, TP53 R273L mutant, used in lung cancer pharmacogenomics.
NCI-H1869
NCI-H1869 (H1869, CVCL_1500, ATCC CRL-5900) is a human lung squamous cell carcinoma cell line established in 1988 from pleural effusion of a 58-year-old male smoker with stage 4 NSCLC; homozygous TP53 p.Met237Ile, MSS, doubling time 51.8 hours.
NCI-H1876
NCI-H1876 (H1876, CVCL_1503, ATCC CRL-5902) is a human small cell lung cancer cell line from a 59-year-old male, with NRAS Q61K and homozygous TP53 R273L mutations, MSS status, and published STR and HLA profiles.
NCI-H1915
NCI-H1915 (H1915, CVCL_1505, ATCC CRL-5904) is a human large-cell non-small cell lung carcinoma cell line established in 1988 from a brain metastasis in a 61-year-old female non-smoker, carrying HRAS Q61L and TP53 mutations.
NCI-H1930
NCI-H1930 (CVCL_1507, ATCC CRL-5906) is a human small cell lung cancer cell line established in 1988 from a lymph node metastasis, with homozygous TP53 p.Gly245Arg, suspension aggregate growth, and extensive CCLE, CellMinerCDB, and NCI SCLC drug-screen data.
NCI-H1944
NCI-H1944 (H1944, CVCL_1508, ATCC CRL-5907) is a human lung adenocarcinoma cell line established in 1988 from a 62-year-old female smoker, carrying heterozygous KRAS G13D, used widely in lung cancer drug and omics studies.
NCI-H196
NCI-H196 (CVCL_1509, ATCC CRL-5823) is a human lung cancer cell line established in 1979 from a metastatic pleural effusion; originally small cell lung cancer, reclassified as lung sarcomatoid carcinoma, with homozygous RB1 and TP53 mutations.
NCI-H1963
NCI-H1963 (H1963, CVCL_1510) is a human small cell lung cancer cell line established in June 1988 from a 56-year-old Black male patient, held as ATCC CRL-5982 and DSMZ ACC-540, with RB1 and TP53 mutations and suspension growth.
NCI-H1975
NCI-H1975 (H1975, CRL-5908, CVCL_1511) is a human lung adenocarcinoma cell line established in 1988 from a nonsmoking female, carrying EGFR L858R/T790M mutations that make it the standard model of EGFR tyrosine kinase inhibitor resistance.
NCI-H1993
NCI-H1993 (CVCL_1512, ATCC CRL-5909) is a human lung adenocarcinoma cell line from a 1988 lymph node metastasis in a 47-year-old female smoker, MET-amplified, TP53-mutant, with sister line NCI-H2073.
NCI-H2009
NCI-H2009 is a human lung adenocarcinoma cell line established in 1988 from a lymph node metastasis in a 68-year-old patient, distributed by ATCC as CRL-5911.
NCI-H2023
NCI-H2023 (H2023, CVCL_1515, ATCC CRL-5912) is a human lung adenocarcinoma cell line from a 26-year-old White male with stage 3A NSCLC, carrying SMARCA4 and TP53 mutations, microsatellite stable, doubling time 32.3 hours.
NCI-H2029
NCI-H2029 (H2029, CVCL_1516, ATCC CRL-5913) is a human small cell lung cancer cell line established in 1988 from a lymph node metastasis of a 69-year-old female smoker, with homozygous RB1 and TP53 mutations, used in DepMap, CCLE, and CellMinerCDB.