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Elevated C-reactive protein
Elevated C-reactive protein (raised CRP, hs-CRP elevation; ICD-11 MA14.15) is a nonspecific blood marker of inflammation from infection, trauma, or chronic disease; normal below 0.3 mg/dL, marked above 10 mg/dL.
Elevated erythrocyte sedimentation rate
Elevated erythrocyte sedimentation rate (ESR, sed rate, Westergren sedimentation rate): red cells settle faster than normal in one hour, a nonspecific marker of inflammation; ICD-11 MA1A.0.
Elevated mood
Elevated mood (ICD-11 MB24.8, 高揚気分) is a symptom of persistently elated or expansive mood, coded under mood/affect signs; pathological when persistent and impairing, it is the entry feature of manic episodes in bipolar I disorder.
Elexacaftor
Elexacaftor (VX-445) is a CFTR corrector used with tezacaftor and ivacaftor as Trikafta/Kaftrio for cystic fibrosis; FDA-approved 2019, binds TMD1/TMD2 site, boxed liver-injury warning.
Elfetabart drozuntecan
DB-1311 (BNT324, elfetabart drozuntecan) is a DualityBio-discovered, BioNTech-partnered antibody-drug conjugate targeting B7-H3 with a topoisomerase-I inhibitor payload P1021, in phase 3 development for metastatic castration-resistant prostate cancer.
Eli Lilly and Company
Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, founded by Colonel Eli Lilly in 1876. It brought the first commercial insulin to market in 1923.
Eligibility Determination
Eligibility determination: applying defined criteria to decide whether a person qualifies for health care programs or benefits, also called eligibility certification. Covers Medicaid MAGI and non-financial rules, SSA disability determinations, Medicare NCDs, and X12 270/271 transactions.
Eliglustat
Eliglustat (Cerdelga) is an oral glucosylceramide synthase inhibitor, a substrate reduction therapy for Gaucher disease type 1 in CYP2D6 extensive, intermediate, or poor metabolizers; approved in the US in 2014 and the EU in 2015, non-inferior to imiglucerase in the ENCORE trial.
Elimination diet
An elimination diet is a diagnostic and therapeutic method that removes suspected food allergens and reintroduces them to identify triggers of food allergies and intolerances.
Elinzanetant
Elinzanetant (Lynkuet) is Bayer's nonhormonal dual NK1/NK3 receptor antagonist for moderate-to-severe menopausal hot flashes; FDA-approved October 24, 2025 and EU-approved November 17, 2025, including breast cancer endocrine-therapy symptoms.
Elivaldogene autotemcel
Elivaldogene autotemcel (SKYSONA, eli-cel) is bluebird bio's autologous lentiviral HSC gene therapy for boys 4-17 with early, active cerebral adrenoleukodystrophy, FDA-approved 2022, carrying a boxed warning for insertional-oncogenesis-related blood cancers.
Elixir
Elixir: a clear, sweetened hydroalcoholic oral drug solution (ethanol roughly 3–40%), a traditional dosage form from Paracelsus-era pharmacy; distinct from syrups by alcohol content, now deprecated by USP in favor of "solution".
Elizabeth Blackwell
Elizabeth Blackwell (1821–1910), British-born physician, first woman to earn an M.D. from an American medical school (Geneva Medical College, 1849); founded the New York Infirmary for Women and Children and its women's medical college, and was first woman on the British Medical Register.
Elizabeth Garrett Anderson
Elizabeth Garrett Anderson (1836–1917) was an English physician, the first openly female recipient of a medical qualification in Britain in 1865, who founded the New Hospital for Women.
Elizabeth Glaser
Elizabeth Glaser (1947-1994), American AIDS activist, contracted HIV from a 1981 blood transfusion, passed it to children Ariel and Jake, and co-founded the Pediatric AIDS Foundation, renamed EGPAF after her death; known for her 1992 DNC speech.
Elizabeth Kenny
Elizabeth Kenny, known as Sister Elizabeth Kenny, was an Australian nurse who developed a hot-pack treatment for polio and founded the Sister Kenny Institute in Minneapolis in 1942.
Elizabeth Wurtzel
Elizabeth Wurtzel (1967-2020), American author of Prozac Nation (1994), the Gen X depression memoir; also wrote Bitch, More, Now, Again, and Creatocracy; died of breast cancer complications at 52.
Elliptical trainer
Elliptical trainer, also called cross-trainer: stationary exercise machine with oval pedal path and moving handlebars for low-impact full-body cardio. Invented commercially by Precor's EFX 544 in 1995; crank-linkage drive, adjustable resistance and stride.
Ellis-Van Creveld syndrome
Ellis-Van Creveld syndrome, also called chondroectodermal dysplasia, is an inherited skeletal disorder causing short limbs, extra fingers, nail and tooth abnormalities, and congenital heart defects.
Elobixibat
Elobixibat (A3309, GOOFICE) is a first-in-class ileal bile acid transporter inhibitor for chronic constipation, approved in Japan in January 2018; dosed 10 mg daily, it raises colonic bile acids, with abdominal pain and diarrhea as main adverse effects.
Eloise (psychiatric hospital)
Eloise, also Wayne County Poorhouse, Eloise Hospital, and Wayne County Psychiatric Hospital, was a Westland, Michigan county complex operating 1832-1979 as poorhouse, asylum, TB sanatorium, and general hospital, peaking at 10,000 patients.
Elongated labia
Elongated labia, also called labia minora hypertrophy, are inner vaginal folds extending beyond the labia majora; a common nonpathologic anatomical variation, culturally valued in parts of Eastern and Southern Africa, and increasingly targeted by labiaplasty surgery.
Elosulfase alfa
Elosulfase alfa (Vimizim, BioMarin) is recombinant N-acetylgalactosamine-6-sulfatase, weekly IV enzyme replacement therapy for MPS IVA (Morquio A); FDA approved 14 February 2014, improves walking and lung function, boxed warning for anaphylaxis.
Elranatamab
Elranatamab, sold as Elrexfio, is a humanized bispecific antibody developed by Pfizer that binds BCMA on myeloma cells and CD3 on T cells, approved in 2023 for relapsed multiple myeloma.
Elsa Brändström
Elsa Brändström was a Swedish nurse who organized Red Cross relief for prisoners of war in Siberia during World War I, earning the nickname Angel of Siberia.
Eluxadoline
Eluxadoline (Viberzi, Truberzi) is a gut-restricted mixed mu/kappa opioid agonist and delta antagonist approved in 2015 for irritable bowel syndrome with diarrhea; 75-100 mg twice daily, contraindicated without a gallbladder.
Elvitegravir
Elvitegravir (EVG, GS-9137, Vitekta) is a once-daily HIV-1 integrase strand transfer inhibitor requiring cobicistat or ritonavir boosting; sold in Stribild (2012) and Genvoya (2015), no longer recommended as initial therapy.
EM-2
EM-2 is a human cell line derived from the bone marrow of a 5-year-old girl with Philadelphia chromosome-positive chronic myeloid leukemia, in second relapse after a bone marrow transplant.
Emactuzumab
Emactuzumab (RG7155) is a humanized anti-CSF1R monoclonal antibody from Roche, now SynOx Therapeutics, that blocks receptor dimerization; it showed 86% ORR in diffuse-type tenosynovial giant cell tumor and is in the phase III TANGENT trial.
Emanuel syndrome
Emanuel syndrome, or supernumerary der(22)t(11;22) syndrome (OMIM 609029), a rare chromosomal disorder from 3:1 malsegregation of a balanced t(11;22), causing congenital anomalies, microcephaly, and severe intellectual disability.