72,234 articles
MMP14
MMP14 (MT1-MMP, matrix metallopeptidase 14) is a type I transmembrane zinc endopeptidase, the first membrane-type MMP (1994), that activates proMMP2 via TIMP2, degrades collagens, sheds CD44, and drives cancer invasion; T17R mutation causes Winchester syndrome.
MMP2
MMP2, also called gelatinase A or 72-kDa type IV collagenase, is a zinc-dependent matrix metalloproteinase degrading type IV/V collagen, fibronectin, laminin, and elastin; uniquely activated at the cell surface by MT1-MMP with TIMP-2, and linked to cancer, cardiovascular, and diabetic disease.
MMP3
MMP3 (stromelysin-1, MMP-3), gene at 11q22.2, encodes a secreted zinc endopeptidase degrading fibronectin, laminin, collagens III/IV/IX/X, and proteoglycans; activates MMP-1 and MMP-9; implicated in arthritis, cancer, fibrosis, and bone.
MMP8
MMP8 (matrix metallopeptidase 8, neutrophil collagenase, MMP-8, EC 3.4.24.34) is a human chromosome 11q22.3 gene encoding a zinc-dependent collagenase stored in neutrophil granules, degrading type I, II, III collagens and serving as a periodontitis biomarker.
MMP9
MMP9 (MMP-9, gelatinase B, 92 kDa type IV collagenase) is a zinc-dependent secreted endopeptidase degrading type IV/V collagen, key to leukocyte migration, inflammation, cancer metastasis, and a difficult drug target; only doxycycline is approved among MMP inhibitors.
MMR vaccine
MMR vaccine: live attenuated combination vaccine against measles, mumps, rubella; two doses at 12–15 months and 4–6 years; 93–97% effective; contraindicated in pregnancy; no autism link.
MMW Fortschritte der Medizin
MMW Fortschritte der Medizin is a German-language medical journal published by Springer Medizin, formed in 1999 from the merger of the Münchener Medizinische Wochenschrift and Fortschritte der Medizin.
MNase-seq
MNase-seq is a sequencing method that maps nucleosome positions genome-wide by digesting DNA with micrococcal nuclease, which cuts exposed linker DNA; with titration controls it also measures chromatin accessibility.
Mnemiopsis
Mnemiopsis is a genus of lobate ctenophores (comb jellies, Bolinopsidae) whose species M. leidyi, the sea walnut, is a major invasive gelatinous predator in Eurasian seas and a leading model for early animal evolution, with a small 2013-sequenced genome supporting ctenophores as sister to all other animals.
MNH study
MNH study (Maternal Newborn Health Registry, MNHR, NCT01073475): NICHD Global Network prospective population-based pregnancy registry since 2008, enrolling about 60,000 women yearly across seven LMIC sites, tracking stillbirth, neonatal, and maternal mortality to 42 days postpartum.
Mniaceae
Mniaceae (Schwägr., 1830) is a moss family in Bryales, type genus Mnium, with about 12 genera and 92 species, broad bordered leaves, hexagonal laminal cells, and a double peristome; nearly worldwide, circumtemperate to circumboreal.
MNNG/HOS Cl #5
MNNG/HOS Cl #5 (CVCL_0439, ATCC CRL-1547), also called MNNG-HOS or HOS-MNNG, is a human osteosarcoma cell line made by MNNG chemical transformation of HOS-TE85; where the MET oncogene was first identified.
Mo's Restaurants
Mo's Restaurants (Mo's Seafood & Chowder), Oregon Coast chain founded 1946 in Newport by Mohava "Mo" Niemi; famous cream-based clam chowder, ~500,000 pounds produced yearly, locations in Newport, Lincoln City, Florence, Cannon Beach, Astoria, Seaside, and PDX airport.
Mo25-like
Mo25-like (IPR013878, Pfam pfam08569) is a helical-repeat protein family whose human members CAB39/MO25α and CAB39L/MO25β scaffold the LKB1-STRAD-MO25 kinase complex and activate SPAK, OSR1, and MST kinases.
Moa
Moa were nine species of large flightless birds endemic to New Zealand, and the only birds with no vestige of a wing, extinct by about 1550 CE.
MobA/VirD2-like, nuclease domain
MobA/VirD2-like nuclease domain (Pfam PF03432, InterPro IPR005094) is the HUH-fold relaxase catalytic domain that nicks plasmid oriT by transesterification during bacterial conjugation, forming a 5'-phosphotyrosine adduct.
MOBIL trial
MOBIL trial (NCT01679977, Mobilität im Alter): completed randomized, open-label, factorial-assignment efficacy trial comparing vibrational-proprioceptive resistance exercise training versus neuromuscular electrical stimulation training in 150 adults aged 65-85 with age-related muscle weakness, run 2008-2015 in Austria and Slovakia by the Ludwig Boltzmann Institute.
Mobile Health Units
Mobile Health Units (MHUs, mobile clinics, mobile medical units) are portable facilities delivering diagnostic and therapeutic care to underserved, rural, and conflict-affected communities, defined in MeSH since 1970 and deployed at national scale in the US and India.
Mobula thurstoni
Mobula thurstoni (bentfin devil ray, Lloyd 1908), a mobulid ray of tropical and temperate seas worldwide, identified by double-curved pectoral fin margins; IUCN Critically Endangered since 2025 due to gill-plate fisheries.
MoCA-B Turkish study
MoCA-B Turkish study (NCT07630688): a completed cross-sectional validation of the Turkish Montreal Cognitive Assessment-Basic in 166 low-education adults at Antalya Training and Research Hospital, finding AUC 0.891 for MCI (cut-off 21) and 0.992 for dementia (cut-off 18).
Mocertatug rezetecan
HS-20089 (GSK5733584, mocertatug rezetecan) is a Hansoh-discovered, GSK-licensed B7-H4-targeted antibody-drug conjugate with a topoisomerase I inhibitor payload (DAR 6) in phase 3 trials for platinum-resistant ovarian cancer.
Mocha Dick
Mocha Dick, also called the White Whale of the Pacific, was a real albino bull sperm whale off Mocha Island, Chile, famous for fighting whalers; recorded by Jeremiah Reynolds in 1839 and inspiring Melville's Moby-Dick.
Mockingbird
Mockingbird, chiefly the northern mockingbird (Mimus polyglottos), a Mimidae songbird famed for mimicry; sings repeated phrases, both sexes sing, ~43 million birds, low conservation concern, open-ended learning questioned.
Moclobemide
Moclobemide (Ro 11-1163, Aurorix) is a reversible, selective MAO-A inhibitor (RIMA) antidepressant synthesized in 1972, launched in Europe in 1992, never US-approved, dosed 300-600 mg/day.
Modadugu Vijay Gupta
Modadugu Vijay Gupta, born 1939, is an Indian fisheries biologist who pioneered low-cost pond aquaculture for the rural poor, earning the 2005 World Food Prize and the label Blue Revolution.
Modafinil
Modafinil (Provigil) is a Schedule IV wakefulness-promoting drug approved in 1998 for narcolepsy sleepiness, also used for OSA and shift work disorder in the US but restricted to narcolepsy in the EU.
Model for End-stage Liver Disease score
The Model for End-stage Liver Disease (MELD) score predicts three-month mortality in chronic liver disease from three blood tests, and has prioritized US liver transplant candidates since 2002.
Model organism
Model organism: a species like C. elegans, Drosophila, yeast, or mouse chosen for lab study of shared biology; Brenner adopted the worm in 1963, and fly genetics began with Castle in 1900.
Model organisms in evolutionary developmental biology
Model organisms in evolutionary developmental biology are the small standardized species set, chiefly fruit fly, roundworm, zebrafish, mouse, and Arabidopsis, through which evo-devo is studied.
Moderate and severe traumatic brain injury
Moderate and severe traumatic brain injury (moderate-severe TBI) is head trauma more severe than mild TBI, defined by GCS below 13 or prolonged loss of consciousness or amnesia.