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Capillary-lymphatic malformation
Capillary-lymphatic malformation (CLM) is a combined slow-flow vascular malformation mixing capillary and lymphatic vessels, classified by ISSVA among combined malformations, occurring isolated or in syndromes such as Klippel-Trenaunay and CLOVES.
Capillary-lymphatic-venous malformation
Capillary-lymphatic-venous malformation (CLVM) is a slow-flow combined vascular malformation of capillaries, lymphatics, and veins in the ISSVA classification; with hypertrophy it is Klippel-Trenaunay syndrome, linked to PIK3CA overgrowth spectra.
Capillary-venous malformation
Capillary-venous malformation (CVM, ORPHA:717611) is a slow-flow combined vascular malformation of capillary plus venous components in one lesion, distinct from CM+VM syndromes like Klippel-Trenaunay.
Capital Financing
Capital financing: funding of long-lived facilities and equipment (MeSH D002202), distinct from operating finance. Covers grants, municipal bonds, capital charges, PPPs, and NHS and US hospital financing history.
Capitellum
Capitellum is a genus of three possibly extinct Caribbean skinks (Marie-Galante, Martinique, St. Croix) erected by Hedges & Conn in 2012, named for their small heads, all Critically Endangered (Possibly Extinct).
Capivasertib
Capivasertib (Truqap, AZD5363) is AstraZeneca's first-in-class oral ATP-competitive AKT1/2/3 inhibitor, FDA-approved in 2023 with fulvestrant for PIK3CA/AKT1/PTEN-altered HR-positive HER2-negative breast cancer and in 2026 for PTEN-deficient prostate cancer.
Caplacizumab
Caplacizumab (Cablivi, caplacizumab-yhdp) is an anti-von Willebrand factor nanobody approved in 2018-2019 for acquired thrombotic thrombocytopenic purpura, added to plasma exchange and immunosuppression; bleeding is its main risk.
Capmatinib
Capmatinib (brand name Tabrecta) is an oral MET inhibitor approved in the US in May 2020, the first targeted therapy for metastatic lung cancer with MET exon 14 skipping.
CAPN2
CAPN2 encodes the large catalytic subunit of calpain 2 (m-calpain), a ubiquitous calcium-activated cysteine protease heterodimerized with CAPNS1, requiring millimolar Ca2+ in vitro, inhibited by calpastatin, and linked to neuronal injury and cancer.
CAPN3
CAPN3 (calpain 3) is the human gene on chromosome 15 encoding calpain-3, a muscle-specific protease; mutations cause limb-girdle muscular dystrophy LGMD R1 (recessive) and LGMD D4 (dominant).
Capnella
Capnella (Gray, 1869), the Kenya tree corals, is a genus of zooxanthellate shallow-water soft corals in Capnellidae, formerly Nephtheidae, with about 18 nominal species from Australia, South Africa, and the tropical Indo-Pacific.
CAPNETZ study
CAPNETZ study: German prospective multicenter observational cohort of community-acquired pneumonia in adults, recruiting since 2002 (DRKS00005274, NCT02139163); over 14,000 patients, largest CAP etiology study in Germany, run by CAPNETZ STIFTUNG.
Capnocytophaga
Capnocytophaga: genus of fastidious, slow-growing Gram-negative bacteria from dog and cat mouths and human oral cavity; causes periodontal disease and, via C. canimorsus, sepsis and meningitis after bites.
Capnography
Capnography, also known as end-tidal CO2 monitoring, continuously measures and displays exhaled carbon dioxide as a waveform, used to confirm tube placement and monitor ventilation.
Capoeta capoeta
Capoeta capoeta, the seven khramulya, is a 41 cm freshwater cyprinid barb of western and Central Asian rivers; plant-feeding, Least Concern, type of the Aralo-Caspian Capoeta group.
Capon
Capon: a castrated, specially fattened male chicken (caponized rooster), prized since ancient Rome. Castration raises intramuscular fat, making the meat tender and juicy; it is the most expensive poultry meat.
Capparaceae
Capparaceae (caper family), Capparaceae Juss., a woody flowering-plant family in Brassicales with about 15 genera and 500 tropical species, including Capparis spinosa; distinguished from Brassicaceae and Cleomaceae by fleshy replum-less fruits and a gynophore.
Capparales
Capparales, also called the mustard-oil order, is a historical plant order name now treated as a synonym of Brassicales, containing Brassicaceae, Capparaceae, and Cleomaceae among 17 glucosinolate-producing families.
Capparis
Capparis (caper genus) is the largest genus of Capparaceae, about 142 Old World tropical and subtropical species from Africa and the Mediterranean to Asia, Australia, and the Pacific; includes Capparis spinosa, the source of culinary capers.
Capping enzyme
Capping enzyme (RNGTT), the eukaryotic RNA guanylyltransferase that adds the 5′ GMP cap to mRNA via a lysyl-GMP intermediate, recruited by Ser5-phosphorylated Pol II CTD; distinct viral capping enzymes are antiviral targets.
Capra (genus)
Capra is the goat genus of Bovidae: domestic goat Capra hircus plus nine wild species (bezoar, ibexes, markhor, turs) of Eurasian and African mountains; C. aegagrus is the sole wild ancestor of domestic goats, domesticated ~10,000 years ago in the Fertile Crescent.
Capreomycin
Capreomycin (Capastat Sulfate), a cyclic polypeptide tuberactinomycin antibiotic from Streptomyces capreolus, was a second-line injectable for MDR-TB; meta-analyses showed worse outcomes, and WHO no longer recommends it.
Capricornis
Capricornis (serows) is an Asian genus of Caprinae goat-antelopes established by Ogilby in 1837 with the Himalayan serow as type; six species per MSW3, four per Mori et al. 2019, 2n=48, mainland serow Vulnerable.
Caprifoliaceae
Caprifoliaceae, the honeysuckle family, is a Dipsacales family of shrubs, climbers, and herbs with opposite leaves, fused petals, and an inferior ovary; broad APG circumscription includes Dipsacaceae and Valerianaceae, about 960 species in 33-41 genera including Lonicera, Dipsacus, and Valeriana.
Caprimulgus
Caprimulgus (Linnaeus, 1758), nightjars, is a genus of crepuscular, nocturnal insectivorous birds in Caprimulgidae, restricted by molecular phylogenetics to Old World species, with about 60 traditionally recognized species worldwide.
Caprin
Caprin (Caprin-1, RNG105; gene CAPRIN1) is a cytoplasmic RNA-binding phosphoprotein that promotes G3BP1 stress granule assembly, regulates dendritic mRNA localization and memory, and causes neurodegeneration or cancer when altered.
Caprina
Caprina is the largest subclade of the caprines (Caprini, Bovidae), containing goats (Capra), sheep (Ovis), and relatives such as Ammotragus, Pseudois, and Hemitragus; sister to Ovibovina, with a late Miocene radiation near 10.96 Mya.
Caprinae
Caprinae, the goat-antelopes, is a bovid subfamily containing goats, sheep, muskox, serows, gorals, chamois, takin, and tahrs in 12 genera; molecular phylogenetics dissolved the classical tribes into a single Caprini sensu lato.
Caprine arthritis/encephalitis
Caprine arthritis/encephalitis (CAE), caused by Lentivirus capartenc (formerly CAEV), is a persistent lentivirus infection of goats related to maedi-visna; spread via colostrum and milk, causing arthritis in adults and leukoencephalomyelitis in kids, with no vaccine.
Caprinidae
Caprinidae (d'Orbigny, 1847) is an extinct family of Lower Cretaceous rudist bivalves with subfamilies Caprininae and Caprinuloidinae, diagnosed by myocardinal characters, originating from Pachytraga and Retha, and radiating on Cretaceous carbonate platforms.