72,234 articles
Captopril
Captopril (Capoten, SQ 14,225) is the first orally active ACE inhibitor, designed rationally at Squibb by Cushman and Ondetti in 1974-75 from carboxypeptidase A inhibitor models, used for hypertension, heart failure, post-MI dysfunction, and diabetic nephropathy.
Capture Hi-C
Capture Hi-C (CHi-C) is a chromatin conformation assay that enriches standard Hi-C libraries for selected loci by hybrid capture, mapping long-range DNA interactions in a targeted many-by-all design.
Capture sequencing
Capture sequencing is a targeted DNA sequencing method that uses biotinylated hybridization probes to enrich selected genomic regions, such as the exome or cancer gene panels, before sequencing.
Capuchin monkey
Capuchin monkey, small New World primate of genera Cebus and Sapajus (gracile and robust capuchins), 1.1–3.3 kg, Central and South American forests; noted for habitual stone-tool nut cracking, high encephalization, and pet-trade pressure.
Capybara
Capybara (Hydrochoerus hydrochaeris, chigüiro): the world's largest rodent, a semi-aquatic South American grazer living in groups near water; IUCN Least Concern, hunted and farmed for meat and leather.
CAR T-cell therapy
CAR T-cell therapy is an immunotherapy in which a patient's T cells are engineered with a chimeric antigen receptor to attack cancer cells, used mainly for blood cancers.
CAR trial
CAR trial (NCT01889992), Cardiac Allograft Remodeling and Effects of Sirolimus, a University of Nebraska heart-transplant study of sirolimus versus remodeling, registered 2013, terminated 2023 with no results posted.
CaR-1
CaR-1 (CaR1, CAR1; CVCL_1116, JCRB0207) is a human rectal adenocarcinoma cell line from a 70-year-old Japanese man's inguinal lymph node metastasis, established in 1977, MSS, with homozygous TP53 p.Val272Met, distinct from CAR receptors and CAR-T.
CAR-NK cell therapy
CAR-NK cell therapy is a cancer immunotherapy in which natural killer cells are engineered with chimeric antigen receptors to attack tumors, offering off-the-shelf donor-derived treatment.
Carabao
Carabao (kalabaw, karabaw): the Philippine swamp-type water buffalo, Bubalus bubalis, introduced around 300 BC, used as a living tractor in rice paddies and for meat, milk, and hide; about 2.6 million head, 99 percent smallholder-owned.
Carabidae
Carabidae (ground beetles, carabids), family Latreille 1802 of beetle suborder Adephaga; about 39,000 predatory, mostly nocturnal, fast-running species worldwide, important pest controllers and bioindicators.
Caracal
Caracal (Caracal caracal), also called desert lynx or rooikat: a medium-sized tufted-eared wild cat of Africa and Asia, IUCN Least Concern globally but rare in Asia, able to leap 3 m to catch birds.
Caracara
Caracara (Merrem, 1826; synonym Polyborus) is a New World falcon genus of terrestrial, scavenging crested caracaras in Falconidae's Polyborinae, including C. plancus, C. cheriway, and extinct C. lutosa and C. creightoni.
Caracara plancus
Caracara plancus, the crested caracara (formerly split as Northern C. cheriway and Southern C. plancus), is a large ground-walking falcon of open habitats from the southern US to Tierra del Fuego, a generalist scavenger-predator listed as Least Concern.
Caracat
The Caracat is a rare hybrid cat created by crossing a wild caracal with a domestic cat, usually a ticked Abyssinian. It is not recognized by major registries like TICA.
Caragana
Caragana (锦鸡儿属), peashrub, a Fabaceae genus of spiny shrubs native from eastern Europe to temperate Asia; 63-105 species, arid Miocene origin in the Junggar Basin, nitrogen-fixing windbreak shrubs like the Siberian peashrub.
Caragea's plague
Caragea's plague (Romanian: ciuma lui Caragea) was a bubonic plague epidemic that devastated Wallachia and its capital Bucharest between 1812 and 1814, the deadliest plague recorded in the Romanian lands.
Caraiba
Caraiba is a monotypic snake genus (Dipsadinae) erected in 2009, holding only Caraiba andreae, the Cuban lesser racer, endemic to Cuba and Isla de la Juventud; distinct from the plant synonym Tabebuia caraiba.
Carambola
Carambola (Averrhoa carambola), also called star fruit, is a Southeast Asian Oxalidaceae tree fruit with a star-shaped cross section; sweet cultivar 'Arkin' dominates Florida's crop, and the fruit is toxic to people with kidney disease.
Caramelo (dog)
The vira-lata caramelo, Portuguese for caramel mutt, is a caramel-colored mixed-breed street dog common in Brazil and much of Latin America, celebrated as a symbol of Brazilian popular culture.
Carangidae
Carangidae, the jacks and pompanos (trevallies, amberjacks, scads), is a family of about 147 marine fish species in order Carangiformes, found in Atlantic, Indian, and Pacific Oceans, commercially important and taxonomically difficult.
Caranx hippos
Caranx hippos, the crevalle jack (also Scomber hippos), is a large Atlantic carangid gamefish reaching 124 cm and 32 kg, a schooling piscivore of continental shelves, IUCN Least Concern.
Caranx vinctus
Caranx vinctus (cocinero, striped jack, barred jack), a Carangidae jack of the tropical Eastern Pacific from Southern California to Peru; 37-38 cm max, coastal to 50 m, commercial fishery, IUCN Least Concern.
CARASAL
CARASAL, cathepsin A-related arteriopathy with strokes and leukoencephalopathy, is a rare autosomal dominant genetic disease causing adult-onset strokes and severe white matter damage, caused by CTSA gene variants and first characterized in 2016.
Carassius carassius
Carassius carassius, the crucian carp (basionym Cyprinus carassius), is a cyprinid fish of Europe and western Asia, anoxia-tolerant, farmed mainly in China, and declining in central Europe.
Carassius gibelio
Carassius gibelio, known as the Prussian carp, gibel carp, or silver crucian carp, is a freshwater cyprinid fish highly invasive in Europe and western Canada.
Caraway
Caraway (Carum carvi), also meridian fennel or Persian cumin, is a biennial Apiaceae herb of temperate Eurasia whose aromatic fruits, rich in d-carvone and limonene, season rye bread and liqueurs and serve as a traditional carminative remedy.
Carbamate kinase
Carbamate kinase (CK, EC 2.7.2.2, ATP:carbamate phosphotransferase) is a homodimeric microbial enzyme interconverting carbamoyl phosphate and ADP with ATP and carbamate, generating ATP in the arginine deiminase pathway and replacing CPS in some archaea.
Carbamazepine
Carbamazepine (Tegretol), a tricyclic sodium channel blocker synthesized at Geigy in 1953, treats epilepsy, trigeminal neuralgia, and bipolar disorder; HLA-B*15:02 screening guides SJS/TEN risk.
Carbamoyl phosphate
Carbamoyl phosphate, a labile high-energy metabolite made from bicarbonate, ammonia or glutamine, and 2 ATP by CPS I or CPS II, feeds both the urea cycle and pyrimidine biosynthesis; CPS1 deficiency causes severe hyperammonemia.