72,234 articles
Deletions of chromosome 18
Deletions of chromosome 18 (18p-, distal and proximal 18q deletion syndromes, ring 18) are partial monosomies causing developmental delay, hypotonia, short stature, and variable features determined by gene dosage.
Deletions of chromosome 19
Deletions of chromosome 19, rare missing segments of the short or long arm, cause microdeletion syndromes including 19p13.13, 19q13.11, and 19q13 deletion syndromes with developmental delay, growth, and craniofacial features.
Deletions of chromosome 2
Deletions of chromosome 2 are losses of genetic material from one of the two copies of chromosome 2, producing several clinically distinct syndromes, including 2q37 deletion and SATB2-associated syndrome.
Deletions of chromosome 20
Deletions of chromosome 20 (20p/20q deletions, del(20q)) are losses of genetic material from chromosome 20, causing Alagille syndrome (JAG1, 20p12), rare 20q11.2q12 syndromes, blood-cancer-associated del(20q), and ring chromosome 20 epilepsy.
Deletions of chromosome 22
Deletions of chromosome 22 (ICD-11 LD44.N): group of chromosomal deletion disorders including 22q11.2 deletion syndrome (CATCH 22 phenotype, DiGeorge/velocardiofacial syndrome), distal 22q11.2 microdeletion, and 22q13 deletion (Phelan-McDermid syndrome), caused mainly by NAHR between low copy repeats.
Deletions of chromosome 3
Deletions of chromosome 3 (partial monosomy 3) are rare chromosomal disorders, including 3p deletion syndrome and 3q29 microdeletion syndrome, caused by loss of a chromosome 3 segment, with intellectual disability, developmental delay, and psychiatric features.
Deletions of chromosome 4
Deletions of chromosome 4 (ICD-11 LD44.4) are partial monosomies of chromosome 4, chiefly Wolf-Hirschhorn syndrome from 4p16.3 deletion (1 in 20,000-50,000 births) and 4q-syndrome, causing developmental delay, distinctive facies, and congenital anomalies.
Deletions of chromosome 5
Deletions of chromosome 5: 5p deletions cause cri du chat (5p minus) syndrome, a congenital disorder with cat-like cry and developmental delay; somatic del(5q) defines 5q- syndrome, a myelodysplastic syndrome subtype.
Deletions of chromosome 6
Deletions of chromosome 6 (ICD-11 LD44.6) are missing segments of the short (6p) or long (6q) arm, causing syndromes driven by FOXC1, DLL1, PRKN, and TBP haploinsufficiency, plus somatic del(6q) in leukemia.
Deletions of chromosome 7
Deletions of chromosome 7 (del(7), -7) are loss of all or part of chromosome 7, causing Williams syndrome (7q11.23), Saethre-Chotzen, Greig, and Silver-Russell syndromes, and common poor-prognosis loss in myeloid malignancies.
Deletions of chromosome 8
Deletions of chromosome 8 (ICD-11 LD44.8; ICD-10-CM Q93.9): chromosomal disorders from missing 8p or 8q segments, including monosomy 8p, 8p12 and 8p23.1 microdeletions, recombinant 8 syndrome, and TRPS II.
Deletions of chromosome 9
Deletions of chromosome 9 (ICD-11 LD44.9): missing segments of the short (9p) or long (9q) arm, causing Alfi/9p deletion syndrome, 9q22.3 microdeletion, Kleefstra syndrome, ring chromosome 9, and common deletions in bladder cancer.
Deletions of the short arm of chromosome 12
Deletions of the short arm of chromosome 12 (12p deletions), rare chromosomal losses including interstitial 12p deletion syndrome with an 809.94 kb minimal critical region at 12p11.23-12p11.22; distinct from tetrasomy 12p (Pallister-Killian syndrome).
Delftia
Delftia is a genus of gram-negative, strictly aerobic Comamonadaceae bacteria (Betaproteobacteria) established by Wen et al. in 1999, with six species including D. acidovorans; known for delftibactin-mediated gold precipitation, bioremediation traits, and rare opportunistic infections.
Delicata squash
Delicata squash (sweet potato squash), a Cucurbita pepo winter squash introduced in 1894 by Peter Henderson & Co., with cream-and-green striped fruit, edible skin, and sweet flesh; revived by Cornell's 2002 AAS-winning Bush Delicata.
Delichon
Delichon, house martins, a genus of four swallow species (urbicum, lagopodum, dasypus, nipalense) breeding across Eurasia; mud nests under eaves, colonial, migratory, white rump.
Deliriant
Deliriants are hallucinogenic drugs, mainly anticholinergic tropane alkaloids like atropine and scopolamine from Datura and other nightshades, that cause delirium by blocking muscarinic acetylcholine receptors, producing the anticholinergic toxidrome.
Delirium
Delirium (acute confusional state, toxic-metabolic encephalopathy) is an acute, fluctuating disturbance of attention and awareness caused by illness, drugs, or withdrawal. Common in hospitalized older adults; screened with CAM, CAM-ICU, or 4AT; treated by correcting the cause.
Delirium tremens
Delirium tremens (DT), the most severe form of alcohol withdrawal syndrome, is withdrawal delirium with tremor, agitation, and confusion occurring in 3-5% of hospitalized alcohol-withdrawal patients; treated with benzodiazepines, optionally phenobarbital.
DELIVER trial (NCT03619213)
DELIVER (NCT03619213), Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure: AstraZeneca phase III trial; dapagliflozin 10 mg cut cardiovascular death or worsening heart failure 18% (HR 0.82) in 6,263 patients with LVEF >40%.
DELIVER trial (NCT04418765)
DELIVER (NCT04418765) is a phase 3b randomized trial of eptinezumab (Vyepti), an anti-CGRP antibody, for migraine prevention in adults with 2-4 prior preventive treatment failures; both 100 mg and 300 mg IV doses cut monthly migraine days more than placebo.
Delivery by elective caesarean section
Delivery by elective caesarean section (ICD-11 JB22.0; ICD-10-CM O82.0) is planned surgical birth via abdominal and uterine incision, usually from 39 weeks; trial evidence shows lower neonatal trauma and incontinence but more wound infection and future-pregnancy risks.
Delivery by emergency caesarean section
Delivery by emergency caesarean section (ICD-11 JB22.1) is surgical birth during pregnancy or labor when vaginal delivery is unsafe or impossible, with NICE category 1 targeted within 30 minutes.
Delonix
Delonix is a genus of 12 species of unarmed trees in the legume family, native to northeastern Africa, western India, and Madagascar, best known for the flamboyant.
Delonix regia
Delonix regia, royal poinciana or flamboyant (gulmohar), a Fabaceae tree native to N & W Madagascar, grown tropics-wide for scarlet flowers; umbrella crown, 40-70 cm pods, Caution status in South Florida.
Delphacidae
Delphacidae (delphacid planthoppers, Leach 1815) is a family of about 2,200 phloem-feeding planthopper species in over 400 genera, diagnosed by a movable hind-tibial spur (calcar), mostly grass-feeding, and including major crop pests such as the brown planthopper.
DelpHi trial
DelpHi-MV (DelpHi trial, NCT01401582) was a German GP-based cluster-randomized trial of nurse-led dementia care management in Mecklenburg-Western Pomerania; 634 participants, reduced neuropsychiatric symptoms and caregiver burden, cost-effective at 24 months.
Delphinidae
Delphinidae, the oceanic dolphin family, includes dolphins, killer whales, and pilot whales: about 37 species of streamlined, echolocating toothed whales with melons, conical teeth, and pods, from 10 m orcas to 1.2 m Hector's dolphins.
Delphinium
Delphinium (larkspur) is a Ranunculaceae genus of 539 accepted annual and perennial herbs with spurred, zygomorphic flowers, native to temperate Old World and North America, toxic via norditerpenoid alkaloids, and a major ornamental cut flower.
Delta (wasp)
Delta (wasp): Old World potter wasp genus (Vespidae, Eumeninae), de Saussure 1855, about 49 species in tropical Africa and Asia; builds pot-shaped mud nests and provisions larvae with caterpillars, notably Delta esuriens.