edgepedia

Life and health

72,234 articles

ENPIC study

ENPIC (Evaluation of Nutritional Practices in the Critical Care patient) is a 2018 Spanish multicenter observational study of 639 ICU patients on artificial nutrition, finding 25.6% mortality linked to severity scores, NUTRIC risk, and protein intake.

ENPP1

ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1, PC-1) is a human transmembrane ectoenzyme that hydrolyzes ATP to generate mineralization-inhibiting pyrophosphate and degrades extracellular 2′3′-cGAMP, damping cGAS–STING antitumor immunity; deficiency causes GACI and ARHR2.

ENPP2

ENPP2 (autotaxin, ATX, LysoPLD) is a human gene on 8q24.12 encoding a secreted 125 kDa lysophospholipase D that converts LPC to LPA; dysregulation links to cancer, fibrosis, and inflammation, with inhibitors in clinical trials.

ENPP3

ENPP3 (CD203c, NPP3) is a human type II transmembrane ectoenzyme of the ENPP1-3 subgroup that hydrolyzes extracellular ATP, UDP-GlcNAc, and cGAMP; it is the basophil activation marker used in allergy testing and a cGAMP-hydrolyzing immune checkpoint over-expressed in clear cell renal cell carcinoma.

Enric Sala

Enric Sala is a Spanish marine ecologist who left a Scripps professorship in 2008 to lead National Geographic's Pristine Seas, which has helped protect over 6.9 million square kilometers of ocean.

ENRICA study

ENRICA (Study on Nutrition and Cardiovascular Risk in Spain) is a nationwide cohort of about 13,000 adults aged 18+ recruited 2008–2010, with Seniors-ENRICA-1 and -2 older-adult subcohorts, studying diet, risk factors, and mortality.

Enrichment analysis

Enrichment analysis, also called gene set enrichment analysis, is a family of statistical methods in bioinformatics testing whether predefined gene sets are overrepresented among genes from genome-wide experiments.

Enrichment culture

Enrichment culture is a microbiology technique that grows a mixed sample under selective conditions favoring a target organism, raising its abundance or recovery for isolation.

Enrico Cappellini

Enrico Cappellini is an Italian paleoproteomics researcher and professor at the University of Copenhagen, known for sequencing ancient proteins from fossils, including Homo antecessor and Homo naledi enamel.

Enrico Coen

Enrico S. Coen, born in Liverpool in 1957, is a British plant molecular geneticist at the John Innes Centre whose snapdragon mutant screens helped establish the ABC model of flower development.

Enrico Di Cera

Enrico Di Cera is an American biochemist and physician, chairman of biochemistry at Saint Louis University, known for over three decades of work on the blood-clotting enzyme thrombin.

Enrico Schwabe

Enrico Schwabe is a malacologist at the Bavarian State Collection of Zoology in Munich whose research centers on chiton systematics and deep-sea molluscs; the sensory Schwabe organ is named after him.

Enrico Tiacci

Enrico Tiacci is an Italian hematologist and associate professor at the University of Perugia known for identifying BRAF-V600E as the cause of hairy cell leukemia in 2011.

Enrique Rodríguez-Boulan

Enrique Rodríguez-Boulan is an Argentine-American cell biologist known for his 1978 discovery that enveloped viruses bud in a polarized manner from epithelial cells, a model for studying epithelial polarity.

Enrique Rozengurt

Enrique Rozengurt is a molecular biologist and Distinguished Professor of Medicine at UCLA who studies growth factor signaling and discovered the protein kinase D family of enzymes.

Enriqueta C. Bond

Enriqueta C. Bond is an American health scientist and philanthropy leader who served as the first full-time president of the Burroughs Wellcome Fund, a private medical science foundation, from 1994 to 2008.

Enriqueta Felip

Enriqueta Felip is a Spanish medical oncologist specializing in thoracic cancer who heads the Thoracic Tumors Unit at Vall d'Hebron in Barcelona and led the IMpower010 lung cancer immunotherapy trial.

Enrofloxacin

Enrofloxacin, sold as Baytril, is a fluoroquinolone antibiotic used almost exclusively in veterinary medicine, first synthesized in 1983 from nalidixic acid and active against Gram-negative and Gram-positive bacteria and mycoplasmas.

Ensartinib

Ensartinib (Ensacove, X-396, Beimeina) is a second-generation ALK/ROS1/MET kinase inhibitor for ALK-positive NSCLC; FDA-approved December 18, 2024 at 225 mg daily, with eXalt3 and ELEVATE trial evidence.

Ensifentrine

Ensifentrine (RPL554), marketed as OHTUVAYRE, is an inhaled dual PDE3/PDE4 inhibitor approved by the FDA in 2024 for maintenance treatment of COPD in adults, dosed 3 mg twice daily by jet nebulizer.

Ensifera

Ensifera is a name for two taxa: the cricket and katydid suborder of Orthoptera, and a hummingbird genus whose sword-billed hummingbird has the longest bill of any hummingbird.

Ensovibep

Ensovibep (MP0420) is a five-domain DARPin antiviral by Molecular Partners and Novartis that blocks SARS-CoV-2 spike-ACE2 binding; positive in EMPATHY phase 2 but futile in hospitalized ACTIV-3/TICO patients, then deprioritized.

Ensure

Ensure, Abbott's adult oral nutritional supplement brand introduced in 1973, offers shakes and powders (Original, Plus, Max Protein, Complete, Enlive) providing complete balanced nutrition for malnourished patients, recovery, and healthy aging.

Ent-Copalyl diphosphate synthase

Ent-copalyl diphosphate synthase (CPS, EC 5.5.1.13), also called ent-kaurene synthetase A, is a class II diterpene cyclase converting GGPP to ent-CPP, the first committed step of gibberellin biosynthesis in plants, fungi, and bacteria.

Ent-kaurene synthase

Ent-kaurene synthase (KS, EC 4.2.3.19) is a class I diterpene synthase that converts ent-copalyl diphosphate into ent-kaurene, feeding gibberellin biosynthesis in plants; related enzymes also occur in rhizobia and fungi.

Entacapone

Entacapone (Comtan) is a reversible peripheral COMT inhibitor taken with levodopa/carbidopa to treat wearing-off motor fluctuations in Parkinson's disease; approved 1998 (EMA) and 1999 (FDA), 200 mg tablets, up to 10 daily.

Entada

Entada (Adans., 1763) is a pantropical legume genus (Fabaceae, Caesalpinioideae) of lianas and trees, 40 species after Elephantorrhiza was merged in 2022, with metre-long pods, sea-heart drift seeds, and saponin-rich medicinal uses.

Entamoeba

Entamoeba: genus of anaerobic parasitic amoebae of the human gut and mouth; E. histolytica causes amoebiasis (34-50 million symptomatic cases, ~55,000-100,000 deaths yearly), while E. dispar, E. moshkovskii, E. coli and E. gingivalis are commensals.

Entamoeba coli

Entamoeba coli, a nonpathogenic commensal intestinal ameba of humans (Grassi, 1879), distinguished by octonucleate cysts of 10–35 µm and sluggish trophozoites with eccentric karyosomes; must be differentiated from pathogenic E. histolytica.

Entamoeba histolytica

Entamoeba histolytica, the pathogenic intestinal amoeba causing amebiasis and amebic liver abscess; distinguished from harmless E. dispar; cyst-transmitted, diagnosed by antigen tests and PCR, treated with antibiotics.